ADRFA Listing of Faculty Publications

1998 Publications

• Journal Articles

  1. Arai, A., Lynch, G., AMPA receptor desensitization modulates synaptic responses induced by repetitive afferent stimulation in hippocampal slices. Brain Res. 799:235-242, 1998.

  2. Arai, A., Lynch, G., The waveform of synaptic transmission at hippocampal synapses is not determined by AMPA receptor desensitization. Brain Res. 799:230-234, 1998.

  3. Bhat, S.G., Wilson, M., Ramkumar, V., Age-dependent reductions in A₁ adenosine receptor expression in rat testes. Am. J. Physiol. 274:C1057-C1064,1998.

  4. Chakravarty, D.N., Faingold, C.L., Comparison of neuronal response patterns in the external and central nuclei of inferior colliculus during ethanol administration and ethanol withdrawal. Brain Research 783:102-108, 1998.

  5. Chen, X., Liu, L.Y., Li, Z.F., Lee, T.J-F., Cardiovascular protective effects and NO-mediated cerebrovasorelaxant effects of extract of Ginkgo biloba leaves. Natl. Med. J. China 78:692-695 (with English abstract), 1998.

  6. Costello, T., Watkins, L., Straign, M., Bean, W., Toth, L.A., Rehg, J.E., Effectiveness of rack sanitation procedures for elimination of bacteria from automatic watering manifolds. Contemp. Topics Lab. Anim. Sci. 37:50-51, 1998.

  7. Das, D., Sasaki, Y.F., Rothe, T., Premkumar, L.S., Takasu, M., Crandall, J.E., Dikkes, P., Connor, D.A., Rayudu, P.V., Cheung, W., Chen H.-S.V., Lipton, S.A., Nakanishi, N., Increased NMDA current and spine density in mice lacking a novel NMDAR subunit, NR3A. Nature 393:377-381, 1998.

  8. Dube, S.N., Husain, K., Sugendran, K. Vijayaraghavan, R., Somani, S.M., Dose response of sulphur mustard : behavioral and toxic signs in rats. Ind. J. Physiol. Pharmacol. 42:389-394, 1998.

  9. Faingold, C.L., Locomotor behaviors in generalized convulsions are hierarchically driven from specific brain-stem nuclei in the network subserving audiogenic seizure. Ann. New York Acad. Sci. 860:566-569,1998.

  10. Faingold, C.L. N'Gouemo, P., Riaz, A., Ethanol and neurotransmitter interactions - from molecular to integrative effects. Progress in Neurobiology 55:509-535, 1998.

  11. Husain, K., Morris, C, Whitworth, C., Trammel, G.L., Rybak, L.P., Somani, S.M., Protection by ebselen against cisplatin-induced nephrotoxicity: antioxidant system. Mol. Cell. Biochem. 178:127-133, 1998.

  12. Husain, K., Somani, S.M., Effect of exercise training and chronic ethanol ingestion on cholinesterase activity and lipid peroxidation in blood and brain regions of rat. Prog. Neuropsychopharmacol. Biol. Psychiat. 22:411-423, 1998.

  13. Husain, K., Somani, S.M., Interaction of exercise training and chronic ethanol ingestion on testicular antioxidant system in rat. J. Appl. Toxicol. 18:421-429,1998.

  14. Krenning, J., Hughes, L.F., Caspary, D.M., Helfert, R.H., Age-related subunit changes in the cochlear nucleus of Fischer-344 rats. Laryngoscope 108(1):26-31, 1998.

  15. Li, Y., Evans, M.S., Faingold, C.L., In vitro electrophysiology of neurons in subnuclei of rat inferior colliculus. Hearing Res. 121:1-10, 1998.

  16. Nie, Z.,. Mei, Y., Malek, R.L., Marcuzzi, A., Lee, N.H., Ramkumar, V., Activation of nerve growth factor receptor (p75) down-regulates A_2A adenosine receptors in PC12 cells. Mol. Pharmacol. 56:947-954, 1998.

  17. Nie, Z., Mei, Y., Ford, M., Rybak, L., Marcuzzi, A., Ren, H., Stiles, G.L., Ramkumar, V., Oxidative stress increases A₁ adenosine receptor expression by activating nuclear factor kB. Mol. Pharmacol. 53:663-669,1998.

  18. Opp, M.R., Toth, L.A., Somnogenic and pyrogenic effects of interleukin-1 and lipopolysacharide in intact and vagotomized rats. Life Sci. 62:923-936, 1998.

  19. Rehg, J.E., Toth, L.A., Rodent quarantine programs: purpose, principles and practice. Lab Anim. Sci. 48:438-447, 1998.

  20. Somani, S.M., Husain, K., Schrolff, E.C., Interaction of ethanol and nicotine on antioxidant enzymes and lipid peroxidation in subregions of rat brain. Res. Commun. Alcohol & Subs. Abuse 19:75-90,1998.

  21. Struble, R.G., Dhanraj, D.N., Wilson, M., Wang, R., Ramkumar, V., Beta amyloid precursor protein (APP), GAP43 and the G-protein, G, are differentially regulated during olfactory nerve regeneration in adult rat. Brain Res. 780:129-137,1998.

  22. Toth, L.A., Chaudhary, M.A., Developmental alterations in auditory arousal from sleep in healthy and virus-infected neonatal cats. Sleep 21:143-152, 1998.

  23. Toth, L.A., Williams, R.W., Genetic analysis of complex quantitative traits using inbred mice. Sleep Res. Soc. Bull. 4:50-56, 1998.

  24. Toth, L.A., Rehg, J.E., Effects of sleep deprivation and other stressors on the immune and inflammatory responses of influenza-infected mice. Life Sci. 63:701-709, 1998.

  25. Yu, J.G., Kimura, T., Chang, X.F., Lee, T.J-F., Segregation of VIPergic-nitric oxidergic and cholinergic-nitric oxidergic innervation in porcine middle cerebral arteries. Brain Res. 801:78-87, 1998.

  26. Zhang, W., Edvinsson, L., Lee, T.J-F., Mechanism of nicotine-induced relaxation in the porcine basilar artery. J. Pharmacol. Exp. Ther. 284:790-797, 1998.

1999 Publications

• Journal Articles

  1. Abbott, S.D., Hughes, L.F., Bauer, C.A., Salvi, R.J., Caspary, D.M., Detection of glutamic acid decarboxylase isoforms in rat inferior colliculus following acoustic exposure. Neuroscience 93:1375-1381, 1999.

  2. Backoff, P.M., Palombi, P.S., Caspary, D.M., GABA- and glycinergic inputs shape coding of AM in chinchilla cochlear nucleus. Hearing Res. 134:77-88, 1999.

  3. Bhat, S.G., Nie, Z., Ramkumar, V., Cisplatin up-regulates adenosine A₁ receptors in rat testes. Eur. J. Pharmacol. 382:35-43, 1999.

  4. Caspary, D.M., Holder, T.M., Milbrandt, J.C., McKernan, R., Naritoku, D.K., Age-related changes in GABA_A receptor subunit composition and function in the rat auditory system. Neuroscience 93(1):307-312, 1999.

  5. Chakravarty, D.N., Faingold, C.L., The inferior colliculus subnuclei and amygdala play differential roles in the neuronal network for audiogenic seizures. Exp. Neurol. 157:135-141,1999

  6. Faingold, C.L., Casebeer, D.J., Modulation of the audiogenic seizure network by noradrenergic and glutamatergic receptors in the deep layers superior colliculus. Brain Res. 821:392-399, 1999.

  7. Faingold, C.L., Neuronal networks in the genetically epilepsy-prone rat. In: "Jasper’s Basic Mechanisms of the Epilepsies", (Advances in Neurology, Vol. 79) Delgado-Escueta, Olsen, Wilson (Eds.), pp. 311-321, Lippincott-Williams and Wilkins, Philadelphia, 1999.

  8. Faingold, C.L., Randall, M.E., Neurons in the deep layers of superior colliculus play a critical role in the neuronal network for audiogenic seizures: mechanisms for production of wild running behavior. Brain Res. 815:250-258, 1999.

  9. Ishine, T., Yu, J.G., Asada, Y., Lee, T.J-F., Nitric oxide is predominant mediator for neurogenic vasodilation in the porcine pial veins. J. Pharmacol. Exp. Ther. 289:398-404, 1999.

  10. Johnson, S.A,. Luu, N.T., Herbst, T.A., Knapp, R., Lutz, D., Arai, A., Rogers, G.A., Lynch, G., Synergistic interactions between ampakines and antipsychotic drugs. J. Pharmacol. Exp. Ther. 289:392-397, 1999.

  11. Lee, T.J-F., Liu, J., Evans, M.S., Cholinergic mechanisms in cerebral neurogenic vasodilation. Proc. 10^th Symposium on Defects in Higher Brain Function (ISSN 1344-6851), Tokyo, Japan, pp. 51-56, 1999.

  12. Li, Y., Evans, M.S., Faingold, C.L., Synaptic response patterns of neurons in the cortex of rat inferior colliculus. Hearing Res. 137:15-28,1999.

  13. Liu, J., Lee, T.J-F., Mechanism of prejunctional muscarinic receptor-mediated inhibition of neurogenic vasodilation in porcine cerebral Arteries. Am. J. Physiol. 276:H194-H204, 1999.

  14. Malek, R.L., Nie, Z., Ramkumar, V., Lee, N.H., Adenosine A_2A receptor mRNA regulation by nerve growth factor in TrkA-, Src-and Ras-dependent via extracellular regulated kinase and stress-activated protein kinase/c-Jun NH (2) terminal kinase. J. Biol. Chem. 274:35499-35505, 1999.

  15. Mei, Y., Gawai, K.R., Nie, Z., Ramkumar, V., Helfert, R.H., Age-related reductions in the activities of antioxidant enzymes in the rat inferior colliculus. Hearing Res. 135:169-180, 1999.

  16. N'Gouemo, P., Faingold, C.L., The periaqueductal gray is a critical site in the neuronal network for audiogenic seizures: modulation by GABA_A, NMDA and opioid receptors. Epilepsy Res. 35:39-46, 1999.

  17. Nakayama, M., Caspary, D.M., Konrad, H.R., Milbrandt, J.C., Helfert, R.H., Age-related changes in [³H]strychnine binding in the vestibular nuclei of rats. Hearing Res. 127:103-107, 1999.

  18. Premkumar, L.S., Selective potentiation of L-type calcium currents in cardiac myocytes and hippocampal neurons by cocaine. Mol. Pharmacol. 56:1138-1142, 1999.

  19. Rybak, L.P., Somani, S.M., Ototoxicity: amelioration by protective agents. Ann. NY Acad. Sci. 884:143-151, 1999.

  20. Rybak, L.P., Husain, K., Whitworth, C., Somani, S.M., Dose-dependent protection by lipoic acid against cisplatin-induced ototoxicity in rats: antioxidant defense system. Toxicol. Sci. 47:195-202, 1999.

  21. Schlorff, E.C., Husain, K., Somani, S.M., Dose and time dependent effects of ethanol on antioxidant system in rat testes. Alcohol 18:203-214, 1999.

  22. Reddy, K.S., Husain, K., Schlorff, E.C., Scott, R.B., Somani, S.M., Dose response of acute ethanol ingestion on antioxidant defense system in rat brain subcellular fractions. Neurotoxicology 20:977-988, 1999.

  23. Scott, R.B., Reddy, S.K., Husain, K., Somani, S.M., Time course response of ethanol on hepatic antioxidant system and cytochrome P-450 II E1 in rat. Environ. Nutritional Interactions 3:217-231,1999 .

  24. Rybak, L.P., Whitworth, C., Somani, S.M., Application of antioxidants and other agents to prevent cisplatin ototoxicity. Laryngoscope 109:1740-1744, 1999.

  25. Schlorff, E.C., Husain, K., Somani, S.M., Dose and time dependent effects of ethanol on plasma antioxidant system in rat. Alcohol 17:97-105, 1999.

  26. Struble, R., Husain, K., Somani, S.M., Response of the olfactory bulb antioxidant system during olfactory nerve regeneration in rats. J. Appi. Toxicol. 19:221-228, 1999.

  27. Toth, L.A., Williams, R.W., A quantitative genetic analysis of slow-wave sleep and rapid-eye-movement sleep in CXB recombinant inbred mice. Behav. Genet. 29:329-337, 1999.

  28. Toth, L.A., Williams, R.W., A quantitative genetic analysis of slow-wave sleep in influenza-infected CXB recombinant inbred mice. Behav. Genet. 29:339-348, 1999.

  29. Toth, L.A., Microbial modulation of arousal. In: "Handbook of Behavioral State Control: Cellular and Molecular Mechanisms". Lydic R, Baghdoyan H (Eds.), Boca Raton, CRC Press, pp. 641-657, 1999.

  30. Toth, L.A., Williams, R.W., A quantitative genetic analysis of locomotor activity in CXB recombinant inbred mice. Behav. Genet. 29:319-328, 1999.

2000 Publications

• Journal Articles

  1. Armour, G.D., Mhaskar, Y., Rybak, L., Dunaway, G.A., Alteration of 6-phosphofructo-1-kinase subunits during neonatal maturation of the rat cochlear cells. Hearing Res. (In Press), 2000.

  2. Bauer, C.A., Brozoski, T.J., Holder, T.M., Caspary, D.M., The effects of chronic salicylate on gabaergic activity in the inferior colliculus of long-evans rats. Hearing Res. 147:175-182, 2000.

  3. Evans, M.S., Li, Y., Faingold, C.L., Inferior colliculus intracellular response abnormalities in vitro associated with susceptibility to ethanol withdrawal seizures. Alcoholism: Clin. Exp. Res. 24(8):1180-1186, 2000

  4. Everson, C.A., Toth, L.A., Systemic bacterial invasion induced by sleep deprivation. Am. J. Physiol. 278:R905-R916, 2000.

  5. Feng, H-J., Faingold, C.L., Modulation of audiogenic seizures by histamine and adenosine receptors in the inferior colliculus. Exp. Neurol. 163:264-270, 2000.

  6. Ishine, T., Bouchelet, I., Hamel, E., Lee, T.J-F., Serotonin 5HT₇ receptors mediate relaxation of porcine pial veins. Am. J. Physiol. 278:H907-H912, 2000.

  7. Kessler, M., Rogers, G., Arai, A., The norbornyl moiety of cyclothiazide determines the preference for flip-flop variants of AMPA receptor subunits. Neurosci. Lett. 287:161-165, 2000

  8. Arai, A.C., Kessler, M., Rogers, G., Lynch, G., Effects of the potent Ampakine CX614 on hippocampal and recombinant AMPA receptors: Interactions with cyclothiazide and GYKI 52466. Mol. Pharmacol. 58:802-813, 2000.

  9. Kuehl-Kovarik, C.M., Partin, M., Premkumar, L.S., Magnusson, K.R., Electrophysiological analysis of NMDA receptor subunit changes in the aging mouse cortex. Mech. Ageing Dev. 115:39-59, 2000.

  10. Lauterborn, J., Lynch, G., Vanderklish, P., Arai, A., Gall, C., Modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons. J. Neuroscience 20:8-21, 2000.

  11. Lee, T.J-F., Mishra, R., Nitrergic neurogenic control of resistance blood vessels. In: "Nitric Oxide and Free radicals". S. Kalsner (Ed.), Birkhauser, New York, pp.160-182, 2000.

  12. Lee, T.J-F., Nitric oxide and the cerebral vascular function. J. Biomed. Sci. 7:16-26, 2000.

  13. Liu, J., Evans, S.M., Brewer, G.J., Lee, T.J-F., N-type Ca²⁺-channels in cultured rat sphenopalatine ganglion neurons: an Immunohistochemical and electrophysiological study. J. Cereb. Blood Flow Metab. 20:183-191, 2000.

  14. Mhaskar, Y., Armour, G.A. and Dunaway, G.A., Alteration of the levels of the M-type 6-phosphofructo-1-kinase mRNA isoforms during neonatal maturation of heart, brain, and muscle. Molecular and Cellular Biochemistry (In Press), 2000.

  15. Milbrandt, J.C., Holder, T.M., Wilson, M.C., Salvi, R.J., Caspary, D.M., GAD levels and muscimol binding in rat inferior colliculus following acoustic trauma. Hearing Res. 147:251-260, 2000.

  16. Mossop, J.E., Wilson, M., Caspary, D.M., Moore, D.R., Down-regulation of inhibition following unilateral deafening. Hearing Res. 147:183-187, 2000.

  17. N’Gouemo, P., Faingold, C.L., Phenytoin administration reveals a differential role of pontine reticular formation and periaqueductal gray neurons in generation of the convulsive behaviors of audiogenic seizures. Brain Res. 859:311-317, 2000.

  18. Scott, R.B., Reddy, K.S., Husain, K., Schlorff, E.C., Rybak, L.P., Somani, S.M., Dose response of ethanol on antioxidant defense system of liver, lung and kidney in rat. Pathophysiology, 7: 25-32, 2000.

  19. Somani, S.M., Husain, K., Influence of exercise induced oxidative stress on the central nervous system. In: "Hand Book of Oxidants and Antioxidants in Exercise". Sen, C.K., Packer, L., Hanninen, O. (Eds.), 2^nd edition, Elsevier Science B.V. Amsterdam, pp 713-754, 2000.

  20. Chen, Y.C., Yang, L.L., Lee, T.J-F., Oroxylin A inhibition of LPS-induced iNOS and COX-2 gene expressions via suppression of NF-kB activation. Biochem. Pharmacol. 59:1445-1457, 2000.

  21. Somani, S, M., Husain, K., Asha, T., Helfert, R., Interactive and delayed effects of pyridostigmine and physical stress on biochemical and histological changes in peripheral tissues of mice. J. Appl. Toxicol. 20:327-334,2 000.

  22. Rybak, L.P., Husain, K., Morris, C., Whitworth, C., Somani, S.M., Effect of protective agents against cisplatin ototoxicity. Am. J. Otology 21:513-520, 2000.

  23. Somani, S.M., Husain, K., Whitworth, C., Trammell, G.L., Malafa, M., Rybak, L.P., Dose-dependent protection by lipoic acid against cisplatin-induced nephrotoxicity in rats: antioxidant defense system. Pharmacol. Toxicol. 96:234-241, 2000.

  24. Taylor, R., Hayes, K.E., Toth, L.A., Evaluation of an anesthetic regimen for retro orbital blood collection from mice. Contemp. Topics Lab. Anim. Sci. 29:14-17, 2000.

  25. Toth, L.A., Oberbeck, C., Straign, C.M., Frazier, S., Rehg, J.E., Toxicity evaluation of prophylactic treatments for mites and pinworms in mice. Contemp. Topics Lab. Anim. Sci. 29:18-21, 2000.

  26. Toth, L.A., Defining the moribund condition as an experimental endpoint for animal research. ILAR Journal 41:72-79, 2000.

  27. Wang, J., Caspary, D.M., Salvi. R.J., GABA_A antagonist causes dramatic expansion of tuning in rimary auditory cortex. NeuroReport 57:1137-1139, 2000.

  28. Xi, X., Toth, L.A., Lipopolysaccharide effects on neuronal activity in rat basal forebrain and hypothalamus during sleep and waking. Am. J. Physiol. 278:R620-R627, 2000.

1998 Abstracts

1. Abbott, S.D., Caspary, D.M., Altered GAD levels in the rat inferior colliculus following acoustic exposure. Assoc. Res. Otolaryngol. 20:809, 1998.

2. Arai, A., Lynch, G., AMPA receptor desensitization modulates synaptic responses to repetitive afferent stimulation but does not determine the waveform of single synaptic responses. Soc. Neurosci. 24:846, #336.7, 1998.

3. Armour, G.A., Mhaskar, Y., Whitworth, C.A., Helfert, R.H., Rybak, L.P., Dunaway, G.A., Immunohistochemical analysis of phosphofructokinase subunits during maturation of the cochlea. Assoc. Res. Otolaryngol. 20:28, #110, 1998.

4. Bauer, C.A., Brozoski, T.J., Caspary, D.M., Rojas, R., Boley, J., Wyder, M., Hindes, A., The effects of salicylate on conditioned suppression behavior and receptor pharmacology in the inferior colliculus of the Long-Evans rat. Assoc. Res. Otolaryngol. 20:811, 1998.

5. Everson, C.A., Toth, L.A., Detection of live bacteria in the lymph nodes of sleep deprived rats. J. Sleep. Res. 7(suppl. 2):81, 1998.

6. Faingold, C.L., Li, Y., Evans, M.S., Decreased GABA-mediated neurotransmission in inferior colliculus neurons in vitro during ethanol withdrawal. Alcoholism: Clin. Exp. Res. 22S:10A, 1998.

7. Faingold, C.L., Li, Y., Evans, M.S., Diminished GABA-A receptor-mediated inhibition in the inferior colliculus may subserve audiogenic seizure susceptibility. Epilepsia 39(S6):37, 1998.

8. Faingold, C.L., Generalized convulsive motor behaviors are hierarchically driven from specific brainstem nuclei in the seizure network. Ann. NY Acad. Sci., 1998.

9. Faingold, C.L., Dynamic changes in network dominance within brainstem nuclei occur during generalized seizures. Dynamical Neuroscience VI (Los Angeles), p. 45, 1998.

10. Husain, K., Somani, S.M., Interaction of exercise training and chronic ethanol ingestion on testicular antioxidant system in rat. Experimental Biology, 1998.

11. Lee, T.J-F., Yu, J.G., O'Brien, W.E., Kimura, T., Ishine, T., Conversion of L-citrulline to L-arginine in porcine cerebral blood vessels. Postcongress Symposium on Biology of Nitric Oxide, Graz, Austria, 1998.

12. Lee, T.J-F., Nitric oxide, anesthetics, and cerebrovascular function. 10^th Asian-Australian Congress of Anesthesiologists, Taipei, Taiwan, 1998.

13. Lipton, S.A., Wong, H.-K., Chan, S. F., Premkumar, L.S., Rothe, T., Chen, H.-S.V., Zhang, D. , Trimmer, J.S., Das, S., Nakanishi, N., Sucher, N.J., NR3A:Single channel currents, electrophysiology of knockout mice, and characterization with a monoclonal antibody. Soc. Neurosci. 24:1271, #504.1, 1998.

14. Liu, J., Lee, T.J-F., Mechanism of presynaptic muscarinic modulation of nitric oxide-mediated cerebral neurogenic vasodilation. Experimental Biology, 1998.

15. Premkumar, L.S.. Selective potentiation of calcium currents in cardiac myocytes and hippocampal neurons by cocaine. Soc. Neurosci. 24:1738, #680.16, 1998.

16. Premkumar, L.S., Auerbach, A., Interaction between Na⁺ and Ca²⁺ in recombinant NMDA receptors channels. Soc. Neurosci. 24:279, #114.5, 1998.

17. Toth, L.A., Book review on "Clinical laboratory animal medicine: an introduction," by Hrapkiewicz K, Medina L, Holmes DD. J. Am. Vet. Med. Assoc. 213:973, 1998.

18. Xi, X., Toth, L.A., Interleukin-1 effects on neuronal activity in rat central amygdala. The Physiologist 41:379, 1998.

19. Yu, J.G., Chang, X.F., Lee, T.J-F., Segregation of cerebral vascular VIPergic-nitric oxidergic and cholinergic-nitric oxidergic innervation in the pig. Soc. Neurosci. 24:110, 1998.

20. Zhang, W., Edvinsson, L., Lee, T.J-F., Nicotine-induced NO-mediated cerebral neurogenic vasodilation is dependent on intact adrenergic innervation. IUPHAR, Munchen, Germany, 1998.

1999 Abstracts

1. Arai, A., Kessler, M., Phillips, D., Sonnenberg, J., Chamberlin, R., Lynch, G., Effects of newly developed benzothiadiazide compounds on AMPA receptor mediated currents and synaptic responses. Soc. Neurosci. 25:1489, #594.11, 1999.

2. Armour, G.A., Mhaskar, Y., Whitworth, C.A., Helfert, R.H., Rybak, L.P., Dunaway, G.A., Characterization of PFK subunit proteins and incidence of apoptosis in marginal stria vascularis cells and the outer hair cells of the rat. Assoc. Res. Otolaryngol. 21:14, #57, 1999.

3. Dunaway, G.D., Faingold, C.L., Presentation of pharmacology within an organ-system based mutidisciplinary integrated sophomore medical curriculum. International Association of Medical School Examiners Proceedings, A-18, 1999.

4. Faingold, C.L., Li, Y., Evans, M.S., Ethanol withdrawal in vivo enhances glutamate- mediated neurotransmission in inferior colliculus neurons in vitro. Alcoholism: Clin. Exp. Res. 23, 19A: 1999.

5. Faingold, C.L., Feng, H-J., Histamine receptors in the inferior colliculus differentially modulate audiogenic seizure susceptibility in genetically-epilepsy prone rats as compared to ethanol-withdrawn rats. Fifth IBRO World Congress (Israel) p. 184, 1999.

6. Faingold, C.L., Naritoku, D.K., Randall, M.E.,The role of inhibitory and excitatory glycine receptors in modulation of audiogenic seizures in the inferior colliculus (IC). Epilepsia 40(S7):39,1999.

7. Faingold. C.L., Selective alterations in seizure network function induced by anticonvulsant drugs. Dynamical Neuroscience VII (Miami), p. 38, 1999.

8. Feng, H-J., Faingold, C.L., Histamine H₁ receptors in amygdala negatively modulate audiogenic kindling in genetically epilepsy-prone rats. Soc. Neurosci. 25:1609, 1999.

9. Holder, T.M., Caspary, D.M., Age-related changes in selective benzodiazepine binding in the inferior colliculus. Assoc. Res. Otolaryngol. 21:222, 1999.

10. Husain, K., Somani, S.M., Influence of physical stress and pyridostigmine on cholinesterase activity in blood and brain regions of male and female mice. FASEB J. 13:818.3A, 1999.

11. Somani, S.M., Husain, K., Scott, B., Verhulst, S., Reddy, K.S., Montrey, R., Helfert, R. Delayed and interactive effects of pyridostigmine and physical stress on biochemical indices in peripheral and cerebral tissues of mice. FASEB J. 13:818.4A, 1999.

12. Husain, K. ,Whitworth, C., Rybak, L.P., Somani, S.M., Dose dependent protection by lipoic acid against cisplatin-induced nephrotoxicity in rats: antioxidant defense system. Toxicologist 48:934A,1999.

13. Ishine, T., Bouchelet, I., Hamel, E., Lee, T.J-F., 5-HT₇ receptors mediate porcine pial venous relaxation. Experimental Biology, 1999.

14. Ishine, T., Bouchelet, I., Hamel, E., Lee, T J-F., Serotonin 5-HT₇ Receptors mediate relaxation of porcine pial veins. Brain ‘99, Copenhagen, 1999.

15. Ishine, T., Yu, J-G, Asada, Y., Lee, T J-F., Nitric oxide is the predominant mediator for neurogenic vasodilator in porcine pial veins. Brain ‘99, Copenhagen, 1999.

16. Jagannathan, R., Husain, K., Reddy, K.S., Somani, S.M., Pyridostigmine and exercise interaction on cardiac antioxidant defense system in mice. Toxicologist 48:960A, 1999.

17. Lee, T.J-F., Liu, J., Evans, M.S., Presynaptic modulation of NO-mediated cerebral neurogenic vasodilation. 8th Southeast Asian-Western Pacific Regional Meeting of Pharmacologists, 1999.

18. Lee, S.H., Premkumar, L.S., Inhibition of capsaicin induced currents by cocaine. Soc. Neurosci. 25:2255, #897.8, 1999.

19. Lin, S.H., Arai, A., Civelli, O., Prolactin releasing peptide (PPRP) suppresses absence seizures by modulating neurotransmission through AMPA receptors. Soc. Neurosci. 25:956, #387.6, 1999.

20. Lin, S.H.S., Arai, A., Vergnes, M., Nothaker, H-P, Huguenard, J.R., Leslie, F.M., Civelli, O., Prolactin releasing peptide (PRRP) suppresses absence seizures by modulating neurotransmission through AMPA receptors. Soc. Neurosci. 25:956, #387.6, 1999.

21. Liu, J., Evans, S.M., Lee, T.J-F., N-type Ca²⁺channels in cultured rat sphenopalatine ganglion neurons: an electrophysiological and morphological study. Experimental Biology, 1999.

22. Liu, J., Evans, S.M., Lee, T.J-F., Presynaptic M₂-receptors mediate inhibition of N-type Ca²⁺ channels in cerebral perivascular NOergic nerves. Soc. Neurosci. 25:1504, 1999.

23. Mishra, R., Khardori, N., Lee, T.J-F., Cerebrovascular tone regulation in septic shock: Role of NF-kappa B-dependent L-citrulline mediated relaxation. SIU School of Medicine Symposium, 1999.

24. Phillips, D.P., Sonnenberg, J.D., Vaswani, R.G., Kleisli, T., Krutzik, P.O., Arai, A., Kessler, M., Lynch, G., Chamberlin, A.R., Alkyl-benzothiadiazides: A new subgroup of AMPA receptor modulators with improved affinity. American Chemical Society, 1999.

25. Reddy, K.S., Husain, K., Schlorff, E.C., Somani, S.M., Dose response of ethanol on antioxidant defense system in brain subcellular fractions of rat. FASEB J. 13:666.6A, 1999.

26. Schatteman, T.S., Hughes, L.F., Hancock, K.E., Larsen, D.L., Caspary, D.M., SAM coding in DCN output neurons of young adult FBN1 rats: effects of different modulation depths and background noise. Assoc. Res. Otolaryngol. 21:141, 1999.

27. Scott, R.B., Husain, K., Reddy, K.S., Rybak, R., Somani, S.M., Dose response of ethanol in relation to the antioxidant defense system of the liver, lung and kidney in rats. Toxicologist 48:925A, 1999.

28. Scott, R.B., Reddy, K.S., Husain, K., Somani, S.M., Chronic and withdrawl effects of ethanol and nicotine on the antioxidant defense system in rat. FASEB J. 13:666.7A, 1999.

29. Somani, S.M., Husain, K., Whitworth, C., Rybak, L.P. Dose dependent protection by lipoate against cisplatin induced ototoxicity in rats: antioxidant defense system. Toxicologist 48:929A, 1999.

30. Somani, S.M., Husain, K., Rybak, L.P., Role of natural and synthetic compounds as protectors of antioxidant defense system against cisplatin-induced nephro and ototoxicity. International Pharmacology, New Delhi, India, 1999.

31. Somani, S.M., Husain, K., Oxidative stress and neurodegenerative diseases. Indian Academy of Neuroscience, Gwalior, India, 1999.

32. Toth, L.A., Opp, M.R., Lipopolysaccharide-induced sleep responses in interleukin-10 deficient mice. FASEB J. 13:A147, 1999.

33. Toth, L.A., Williams, R.W., A quantitative trait locus for slow-wave sleep in influenza-infected CXB recombinant inbred mice. Sleep Res. Online 2(Suppl. 1):560, 1999.

34. Toth, L.A., Williams, R.W., A quantitative trait locus for light-phase slow-wave sleep in influenza-infected mice. The Physiologist 42:A4, 1999.

35. Toth, L.A., Williams, R.W., A QTL for light-phase slow-wave sleep in influenza-infected CXB recombinant inbred mice. Behav. Genet. 29:371, 1999.

36. Verma-Ahuja, S, Husain, K., Verlhust, S., Espinosa, J.A., Somani, S.M., Delayed effects of pyridostigmine and exercise training on muscle tension in mouse lower extremity. FASEB J. 13:818.5A, 1999.

37. Yang, L., Faingold, C.L., Continuous infusion of GABA or an NMDA antagonist into the inferior colliculus results in the development of audiogenic seizures: relationship to ethanol withdrawal. Soc. Neurosci. 25:1579, 1999.

38. Zhang, W., Edvinsson, L., Lee, T.J-F., Presynaptic adrenergic modulation of NO-mediated cerebral neurogenic vasodilation. Brain ‘99, Copenhagen, 1999.

2000 Abstracts

1. Arai, A., Lynch, G., Effects of AMPA receptor modulators on excitatory synaptic responses at two distinct synapses in hippocampal slices. Soc. Neurosci. 26:903, #339.8, 2000.

2. Asha,T., Husain, K., Helfert, R., Verlhulst, Somani, S.M., Delayed interactive effects of Sarin, pyridostigmine and exercise on the biochemical and histopathological changes in mice. Toxicologist 54:266, 2000.

3. Caspary, D.M., Holder, T.M., Hughes, L.F., Schatteman, T.A., Leroy, S. A., Browning, R.A., Aging-related changes in thresholds and GABA neurochemistry: comparison between two rat strains. Assoc. Res. Otolaryngol. 23:81-82, 2000.

4. Faingold, C.L., Feng, H-J., Audiogenic kindling enhances neuronal responsiveness in the amygdala. Epilepsia 41L1.133, 2000.

5. Feng, H-J., Faingold, C.L., Audiogenic kindling induces plastic changes in the physiology of the pathway from the medial geniculate body to the lateral amygdala. Soc. Neurosci. 26:1775, #660.2, 2000.

6. Holder, T.M., Hughes, L.F., Caspary, D.M., Benzodiazepine modulation of GABA-mediated chloride uptake with age. Assoc. Res. Otolaryngol. 23:82, 2000.

7. Husain, K., Scott, R.B., Somani, S.M., Rybak, L.P., Dose response of carboplatin- induced ototoxicity in rats. Toxicologist 54:180, 2000.

8. Husain, K., Somani, S., Scott, R.B. Whitworth, C. A., Rybak, L.P., Carboplatin-induced hearing loss in a rat model : An electrophysiological and biochemical study. Assoc. Res. Otolaryngol. 23:41, #145, 2000.

9. Lin, B., Chun, D., Kubota, D., Arai, A., Lynch, G., Interaction between recording technique and AMPA receptor modulators. Soc. Neurosci. 26:903, #339.3, 2000.

10. Lin, S.H.S., Arai, A., Wang, Z., Civelli, O., Prolactin releasing peptide (PPRP) receptor interacts with and is clustered by PDZ domain containing proteins. Soc. Neurosci. 26:380, #140.5, 2000.

11. Long, C., Yang, L., Evans, M.S., Faingold, C.L., Ethanol withdrawal results in aberrant membrane properties and synaptic responses in periaqueductal gray neurons associated with seizure susceptibility. Soc. Neurosci. 26:1010, #376.2, 2000.

12. Mishra, R., Lee, T.J-F., L-citrulline-mediated porcine basilar artery relaxation following endotoxin treatment. ASPET, 2000.

13. Raisinghani, M., Casebeer, D., Naritoku, D., Faingold, C.L., Modulation of postictal depression: role of opioid receptor subtypes. Soc. Neurosci. 26:1051, #389.17, 2000.

14. Schatteman, T.S., Hughes, L.F., Caspary, D.M., Age-related loss of inhibitory function in rat DCN output neurons: rate responses. Soc. Neurosci. 26:957, #358.17, 2000.

15. Somani, S.M., Husain, K., Jagannathan, R., Verhulst, S., Delayed and interactive effects of sarin, pyridostigmine and exercise on biochemical indices in mice. US Army Bioscience Review meeting, Hunt Valley, MD, 2000.

16. Toth, L.A., Identifying quantitative trait loci using recombinant inbred mice. ACLAM Forum Proceedings, 2000.

17. Yamamoto, R., Asada, Y., Kobayashi, H., Shiraishi, S., Wada, A., Lee, T.J-F., Nitric oxide generated by NOS-1 increases exocytotic norepinephrine release. Jap. J. Pharmacol. 82(Suppl 1):224, 2000

18. Yang, L., Casebeer, D., Long, C., Faingold, C.L., The neuronal network for ethanol withdrawal seizures requires the periaqueductal gray and deep layers of superior colliculus: focal microinjection studies. Soc. Neurosci. 26:1010, #376.3, 2000.

19. Yang, L., Faingold, C.L., Neuronal firing in the deep layers of superior colliculus leads to audiogenic seizures during ethanol withdrawal. Alcoholism: Clin. Exp. Res., 24(5):5A, #12, 2000.