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| Research
Profile - Rital Trammell |
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| Department/Division: |
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Email
Address: |
| Surgery/Orthopaedics |
rtrammell@siumed.edu |
| Office
Location: |
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Location
of Laboratory: |
| 911
N. Rutledge, room 1310E Springfield |
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911 N. Rutledge,
room 330 |
| Office
Phone Number: |
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Laboratory
Phone Number: |
| 217-545-4968 |
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217-545-7780 |
| Willing
to mentor medical students and / or residents?
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Yes |
| Research
Interests: |
Antitumor immune
response.
Wear of orthopaedic implants, including systemic release
of wear debris.
Development of novel nanocoatings to reduce in vivo
wear of orthopaedic implants. |
| Techniques
and Methodologies: |
standard molecular
biology and immunology techniques, including RNA and
DNA isolation, cloning, cDNA library construction, immumoblots,
Northern blots, cell culture, ELISA, proliferation assays,
cytotoxicity assays |
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Equipment:
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Thermocycler,
gel electrophoresis equipment, shaker incubator, cell
culture biohood and incubator, -80 degree freezer, sonicator |
Current
Collaborators:
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D. Gordon Allan,
MD
Yin Yuan Mo, PhD
Peter Filip, PhD
Manish Paliwal, PhD
Michael Pranzatelli, MD
Edward J. Moticka, PhD |
| Current
and Pending Awards: |
Opsoclonus-Myoclonus
Syndrome in Neuroblastoma: Identification of Novel Cerebellar
and Tumor Autoantibodies. William E. McElroy Foundation,
8/1/2002-7/31/2004. PI: Rita Trammell, and CoI: Mike
Pranzatelli and Edward J. Moticka.
Role of Ubc9 in Drug Resistance. William E. McElroy
Foundation, 8/1/2004-7/31/2006. PI: Rita Trammell, and
CoI: Yin Yuan Mo. |
| Publications:
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1.
Chilvers M, Vejvoda H, Trammell R, et al.: Trochanteric
fixation in total hip arthroplasty using the S-ROM
bolt and washer. J Arthroplasty 17:740, 2002
2. Allan DG, Trammell R: The role of arthroscopy in
the evaluation and management of the problematic total
knee arthroplasty. Indian Journal of Orthopaedics
36:80, 2002
3. Trammell, R.; Johnson, C.; Barker, J.; Bell, R.;
Allan, D.G.: "MDR-1 Gene Expression Does Not
Increase During Tumor Progression in the MGH-OGS Murine
Osteosarcoma Tumor Model," Journal of Orthopaedic
Research, Vol. 18 (3), 2000; 449-455.
4. Powers, L.; Trammell, R.; L‚Hommedieu, C.;
Allan, D.G.: "MDR-1 Gene Expression in Human
Soft Tissue Sarcomas: Relation to Clinical Outcome."
The Journal of Bone and Joint Surgery Orthopaedic
Proceedings, Supplement I, Vol. 81-B: 100. 1999.
5. Trammell, R.; Powers, L.; Jewett, T.; Allan, D.G.:
"Expression of Multidrug-Resistance-Associated
Protein (MRP) in Adult Soft Tissue Sarcomas: Relation
to Clinical Outcome." Mid-America Orthopaedic
Association, (submitted).
6. Caronis, G.; Trammell, R.; Allan, D.G.: "The
Effect of HBO and GM-CSF on Wound Healing Variables
and TGF-B1 Levels in Doxorubicin Compromised Wounds."
Orthopaedic Transactions, Vol. 22(2):478. 1998-1999
7. Trammell, R.; Johnson, C.; Barker, J.; Allan, D.G.:
"Expression of the Multidrug Resistance Gene
in a Murine Osteogenic Sarcoma Tumour Model during
Tumour Progression". Orthopaedic Transactions,
Vol 22(2): 476. 1998-1999
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