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| Research Profile - Thomas
J. Brozoski |
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| Department/Division: |
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Email
Address: |
| Surgery/Otolaryngology |
tbrozoski@siumed.edu |
| Office
Location: |
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Location
of Laboratory: |
| 801
N. Rutledge, Rm 3205 |
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801
N. Rutledge, Rm 3205 |
| Office
Phone Number: |
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Laboratory
Phone Number: |
| (217)
545-6583 |
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| Willing
to mentor medical students and / or residents?
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Yes |
| Research
Interests: |
Pathophysiology
of tinnitus; tinnitus therapeutics; sensory processes;
psychophysics |
| Techniques
and Methodologies: |
behavioral
test methods; stereotaxic neurosurgery; single-unit
electrophysiology; sensory evoked potential measurement;
neural lesions; neurohistology; digital image analysis. |
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Equipment:
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Acoustic
isolation chambers; small-animal operant conditioning
chambers; stereotaxic surgical instrumentation; ABR
instrumentation; B&K Pulse sound measurement system
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Current
Collaborators:
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Carol
A. Bauer, M.D.; Donald Caspary, Ph.D. |
| Current
and Pending Awards: |
Tinnitus
Research Consortium
Co-investigator, The effect of tinnitus retraining
therapy on subjective and objective measures of chronic
tinnitus. $ 269,315, 2005-2007.
Tinnitus
Research Consortium
Co-investigator, Clinical efficacy of gabapentin as
a treatment for noise-induced and age-associated tinnitus.
$186,000. 2003-2005.National Institute on Deafness
and Communicative Disorders
Co-investigator, Peripheral and central mechanisms
of tinnitus generation, # DC04830-01A1, 2002-2006,
$1,065,280, 2002 ˆ 2006. |
| Publications:
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Brozoski TJ, Caspary DM, Bauer CA, (2005) Marking multi-channel
silicon-substrate electrode recording sites using radiofrequency
lesions. J. Neurosci. Methods. (in press)
Bauer CA, Brozoski TJ. (2005). Cochlear structure and
function after round window application of ototoxins.
Hear Res, 201:121-31
Brozoski TJ, Bauer CA, (2005). The effect of dorsal
cochlear nucleus ablation on tinnitus in rats. Hear
Res, available online, 5-19-05
Brozoski TJ, Bauer CA, Caspary DM (2002). Elevated fusiform
cell activity in the dorsal cochlear nucleus of chinchillas
with psychophysical evidence of tinnitus. Journal of
Neuroscience 22: 2383-2390.
Bauer CA, Brozoski TJ (2001). Assessing tinnitus and
prospective tinnitus therapeutics using a psychophysical
animal model. Journal of the Association for Research
in Otolaryngology. 2, 54-64.
Bauer CA, Brozoski TJ, Holder TM, Caspary DM (2000).
Effects of chronic salicylate on GABAergic activity
in rat inferior colliculus. Hearing Research. 141, 175-182.
Bauer CA, Brozoski TJ, Rojas R, Boley J, Wyder M (1999).
A behavioral model of chronic tinnitus in rats. Otolaryngology
ˆ Head and Neck Surgery. 121(4), 457-462. |
Optional-CV
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