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| Research
Profile - Michael R. Pranzatelli, MD |
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| Department/Division: |
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Email
Address: |
| Neurology |
mpranzatelli@siumed.edu |
| Office
Location: |
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Location
of Laboratory: |
| Springfield
- Moy Building, third floor |
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801
North Rutledge, Room 2359 |
| Office
Phone Number: |
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Laboratory
Phone Number: |
| (217)
545-7635 |
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(217)
545-6523 |
| Willing
to mentor medical students and / or residents?
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Yes |
| Research
Interests: |
neuroimmunology
of paraneoplastic syndromes, brain neurochemistry, myoclonus,
cerebellar disorders |
| Techniques
and Methodologies: |
CSF
Lymphocyte immunophenotyping by flow cytometry, Western
blots, receptor binding assays |
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Equipment:
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N/A |
Current
Collaborators:
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Anna
Travelstead, Steve Verhulst, Ed Moticka, Rita Trammell,
Amy Arai, Markus Kessler |
| Current
and Pending Awards: |
Current
grants
Title: "A Phase I Clinical Trial of Rituximab for
Pediatric Opsoclonus-myoclonus," Role: PI, Agency:
Genentech, Inc./Biogen Idec, Co.
Title: "Immunophenotyping of cerebrospinal fluid
lymphocytes in Tourette Syndrome," Role: PI, Agency:
Tourette Syndrome Association. |
| Publications:
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Pranzatelli
MR, Travelstead AL, Tate ED, et al. B- and T-cell markers
in opsoclonus-myoclonus syndrome: immunophenotyping
of CSF lymphocytes. Neurology 62 (9): 1526-1532, 2004.
Pranzatelli MR, Travelstead AL, Tate ED, et al. CSF
B-cell expansion in opsoclonus-myoclonus syndrome: a
biomarker of disease activity. Movement Disorders, in
press.
Pranzatelli MR, Hyland K, Tate ED, et al. Evidence of
cellular immune activation in opsoclonus-myoclonus:
cerebrospinal fluid neopterin. Journal of Child Neurology,
in press.
Pranzatelli MR. Myoclonus in childhood. Seminars in
Pediatric Neurology 10:41-51, 2003.
Pranzatelli MR, Tate ED, Wheeler A, et al. Screening
for autoantibodies in children with opsoclonus-myoclonus-ataxia.
Pediatric Neurology 27 (5): 384-387, 2002.
Pranzatelli MR, Tate ED, Kinsbourne M, et al. Forty-one
year follow-up of childhood-onset opsoclonus-myoclonus:
cerebellar atrophy, multiphasic relapses, response to
IVIG. Movement Disorders 17 (6):1387-1390, 2002.
Pranzatelli MR, Tate ED, Galvan I, et al. Controlled
pilot study of piracetam for pediatric opsoclonus-myoclonus.
Clinical Neuropharmacology 24:352-357, 2001.
Pranzatelli MR. Friendly fire. Discover, pp 35-36, April
2000.
Pranzatelli MR. Paraneoplastic syndromes: an unsolved
murder. Neuroimmunology issue, Seminars in Pediatric
Neurology 7 (2):118-130, 2000. |
Optional-CV
Web address:
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