Simmons Cancer Institute at SIU School of Medicine

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Molecular Core Facility

The Simmons Cancer Institute at SIU Molecular Core Facility provides various types of services. The facility is also equipped with state-of-the-art instrumentation as listed below. The equipment is accessible to all cancer researchers at SIU-SM.

  • Manual Tissue Arrayer 2 (Chemicon)
  • Alpha Innotech FlorChem 5500
  • Olympus BX41 microscope with digital imaging system
  • Olympus IX71 inverted fluorescence microscope with digital camera
  • Cryostat (Thermo)
  • Microtome and floating water bath (Thermo)
  • Applied Biosystems 7500 Real Time PCR System
  • Bio-Rad 2-D gel systems
  • Savant Integrated SpeedVac
  • Agilent Bioanalyser
  • LN2 storage (MCR Cryogenics XLC 1200)

In addition, we have the following shared equipment is available to all cancer researchers at SIU-SM.

  • Fuji LAS 3000 Luminescent Image Analyzer® for Western blotting, Southern blotting and Northern blotting.  The LAS-3000 imaging system is equipped with both the Pro and Lite Image Reader® Software package for data capture and analysis. 
  • Li-Cor’s Odyssey® Infrared Imaging System equipped with the Odyssey Software package for data acquisition and analysis which includes band sizing and sample quantification. 
  • Konica SRX-201A Film Processor. 
  • Biorad Gene Pulser Xcell® total system. 
  • Beckman Coulter Vi-CELL™ Cell Viability Analyzer and Counter
  • Shimadzu HPLC system with IN/US B-Ram Model 2B Flow-through Radio-Isotope Beta Gamma Detector. 
  • 96-well Fluorometer with one dispenser for use in reporter gene assays, immunoassays, hybridization assays, DNA quantitation, cell adhesion, and quantitation of PCR products. 
  • 96-well Luminometer with one dispenser for reporter gene assays, such as luciferase and galactosidase; luminescent immunoassays; ATP-based assays and DNA hybridization assays.
  • 96-well Spectrophotometer with a cuvette holder for the ability to read from visible to UV wavelengths.