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Clinical Trials

The Simmons Cancer Institute at SIU School of Medicine participates in clinical research through a variety of avenues. The Cancer Institute supports research initiated by our own physicians as well as industry sponsored trials. However, we are able to reach a greater number of patients by participating in both the Central Illinois Community Clinical Oncology Program (CICCOP) and the University of Chicago Phase II Consortium. The CCOP program was created over 20 years ago by the National Cancer Institute to facilitate physician involvement in cancer clinical trials. This program enables patients to obtain access to clinical trials within their own communities and often through their own physicians. The Phase II Consortium is a collaboration of oncologists who work through the National Cancer Institute, the pharmaceutical industry, and various affiliate cancer centers across the US to bring new novel treatments to patients. Access to clinical trials creates more options for our patients.

We have listed those currently open below:

A Phase II Study of Halichondrin B Analog E7389 in patients with advanced Non-Small Cell Lung Cancer (NSCLC) Previously Treated with Taxane.
Principal Investigator: James Wade, M.D., John Godwin, M.D. (SIU)

(217) 545-7929

A Phase II Study of Bortezomib (PS-341) for Patients with Advanced Bronchiolo-Alveolar Carcinoma (BSAC)
Principal Investigator: James Wade, M.D., John Godwin, M.D. (SIU)
Funding: NIH Grant

(217) 545-7929

Comparison of Behavioral Outcomes for Lung Cancer Patients in Educational Versus Working Support Groups.
Principal Investigator: Theresa Boley, RN, MSN, APN/FNP
Contact: Theresa Boley, RN, MSN, APN/FNP
(217) 545-5500

Intraoperative I-125 Brachytherapy Following Sublobar Resection in High Risk Patients with Stage I Non-Small Cell Lung Carcinoma.
Principal Investigator: Stephen Hazelrigg, M.D.
Contact: Theresa Boley, RN, MSN, APN/FNP
(217) 545-5500

Use of Proteomic Analysis Of Serum Samples For Detection of Non-Small Cancer.
Principal Investigator: Stephen Hazelrigg, M.D.
Contact: Theresa Boley, RN, MSN, APN/FNP
(217) 545-5500

Protocol for Obtaining Solid Tissues, Fluids, and Information for research for The SIU Tissue Banking Facility.
Principal Investigator: Stephen Hazelrigg, M.D.
Contact: Theresa Boley, RN, MSN, APN/FNP
(217) 545-5500

A Randomized Phase III Study of Sublobar Resection Versus Sublobar Resection plus Brachytherapy in High Risk Patients with Non-Small Cell Lung Cancer, 3cm or smaller (ACOSOG Z4032).
Principal Investigator: Stephen Hazelrigg, M.D.
Contact: Theresa Boley, RN, MSN, APN/FNP
(217) 545-5500

A Comparative Study of Gross Tumor Volume Definition With or Without PET Fusion for Patients With Non-Small Cell Lung Carcinoma.
Contact: Diana Weyhenmeyer, RN, MA, OCN
(217) 544-6464, extension 45591


For information on other Simmons Cancer Institute at SIU clinical trials, please click here.



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