SIU School of Medicine

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Accuracy of Sagittal Reformatted Computed Tomography in Identification of Pleural Adhesions

IRB Number


Trial Status

Open for Enrollment
Phase 3

Why is this study being done?

The purpose of this study is to investigate the accuracy of the computed tomography (CT) scan in finding scar tissue between the lung and chest wall. A CT scan is a series of x-rays taken from different angles to produce cross-sectional images of the body’s interior. The images are comparable to a loaf of sliced bread. Your doctor can look through each slice individually or use all the slices to form a 3-D image. You have had or will have a CT scan to aid in the diagnosis and treatment of your lung disease. Scar tissue can cause damage to the lungs during surgery. It may increase the risk of the lung tearing and the time that chest tubes are needed after surgery. If scar tissue is able to be identified between the lung and chest wall it may help in the selection of the surgical incision for future patients.

Who is eligible to participate?

You are being asked to take part in this study because you are scheduled to receive lung volume reduction, lung nodule resection, or a lung diagnostic biopsy (not needle biopsy).

What is involved?

We will be collecting information from your medical record to look at the hospital course associated with your surgery, including length of stay, chest tube duration, air leaks, and complications. In addition, the following exams, test or procedures are part of regular care and will be done even if you do not join the study. CT scan in an imaging center. The scan will be taken in the weeks or months before your procedure and takes less than a half hour. Radiologists will assess and grade scar tissue seen on your CT scan. The surgeon will assess and grade the scar tissue during surgery. The findings of the radiologists and the surgeon will be compared to determine accuracy of the CT in measuring scar tissue.

How long is the study?

You will be in this study from the time you sign the consent form until you’re discharged from the hospital or have your chest tubes removed. We anticipate this to be from 3-9 days.

Who can I contact for additional information?

You may contact Theresa Boley, RN, MSN, APN/FNP, CCRP at 217-545-5000 or email

Who is the Principal Investigator of this study?

Theresa Boley, APN

Where is the trial located?

Springfield, Illinois