Please check back soon for new faculty descriptions.
Ralph Glasser, M.D. Office Location: Memorial Medical Center, Springfield Phone Office: 217-788-3790 Research Focus: Clinical Anesthesiology Willing to serve as an MPEE mentor? Yes
Gregory J. Brewer, Ph.D. Office Location: Room 1269, 801 N. Rutledge, Springfield Laboratory Location: Room 1269, 801 N. Rutledge, Springfield Phone Office: 217-545-5230 Laboratory: 217-545-5731 Research Focus: Aging, Alzheimer Disease, Neuronal Network Bioengineering (separate), Brain Cancer gbrewer@siumed.edu Research Area: Aging mitochondrial function in neurons in relation to Alzheimer disease; manipulating neuronal networks in 2D and 3D to understand neuronal coding; novel nutritional treatment for brain tumors Summary: Laboratory experiments will be conducted to advance the field in the above areas. Experience Needed: Prior lab experience helpful. Number of Students: 3 (one in each area) Willing to serve as an MPEE mentor? Yes Larry Hughes, Ph.D. Office Location: 751 North Rutledge, Room 3107, Springfield Laboratory Location: 751 North Rutledge, Room 3106, Springfield 801 North Rutledge, Room 1330, Springfield Phone Office: 217-545-7186 Laboratory: 217-545-7186 Research Focus: Aging, Neurodegenerative Diseases, Psychophysics and Statistics Willing to serve as an MPEE mentor? Yes Robert G. Struble, Ph.D. Office Location: 801 North Rutledge, Room 4373, Springfield Laboratory Location: 801 North Rutledge, Room 4373, Springfield Phone Office: 217-545-4429 Laboratory: 217-545-4429 Research Focus: Alzheimer,s Disease, Regeneration of the Nervous System Willing to serve as an MPEE mentor? Yes
Gregory J. Brewer, Ph.D. Office Location: Room 1269, 801 N. Rutledge, Springfield Laboratory Location: Room 1269, 801 N. Rutledge, Springfield Phone Office: 217-545-5230 Laboratory: 217-545-5731 Research Focus: Aging, Alzheimer Disease, Neuronal Network Bioengineering (separate), Brain Cancer gbrewer@siumed.edu
Research Area: Aging mitochondrial function in neurons in relation to Alzheimer disease; manipulating neuronal networks in 2D and 3D to understand neuronal coding; novel nutritional treatment for brain tumors Summary: Laboratory experiments will be conducted to advance the field in the above areas.
Experience Needed: Prior lab experience helpful. Number of Students: 3 (one in each area) Willing to serve as an MPEE mentor? Yes
Larry Hughes, Ph.D. Office Location: 751 North Rutledge, Room 3107, Springfield Laboratory Location: 751 North Rutledge, Room 3106, Springfield 801 North Rutledge, Room 1330, Springfield Phone Office: 217-545-7186 Laboratory: 217-545-7186 Research Focus: Aging, Neurodegenerative Diseases, Psychophysics and Statistics Willing to serve as an MPEE mentor? Yes
Robert G. Struble, Ph.D. Office Location: 801 North Rutledge, Room 4373, Springfield Laboratory Location: 801 North Rutledge, Room 4373, Springfield Phone Office: 217-545-4429 Laboratory: 217-545-4429 Research Focus: Alzheimer,s Disease, Regeneration of the Nervous System Willing to serve as an MPEE mentor? Yes
Blaine Bartholomew, Ph.D. Office Location: Neckers Building, Room 211, Carbondale Laboratory Location: Neckers Building, Room 202 or 207, Carbondale Phone Office: 618-453-6437 Laboratory: 618-453-6436 or 618-453-1132 Research Focus: Gene Regulation, Chromatin Willing to serve as an MPEE mentor? Yes Ramesh Gupta, Ph.D. Office Location: Neckers, Room 210, Carbondale Laboratory Location: Neckers, Room 206, Carbondale Phone Office: 618-453-6466 Lab: 618-453-6493 Research Focus: Molecular Biology of Archaea (Archaebacteria), Transcription, RNA Processing rgupta@siumed.edu Research Area: Molecular biology of archaea Summary: Our research interests are mainly in the area of gene regulation in archaea (archaebacteria). Archaea are one of the three domains of life; the other two being Bacteria (eubacteria) and Eukarya (eukaryotes). Archaea include methanogens (producing methane), extreme halophiles (growing in two molar to nearly saturated salt concentrations), thermophiles and hyperthermophiles (growing at 65 to 106 degrees C), acidophiles, alkaliphiles, etc. Archaea, like Bacteria, are prokaryotic in organization, but show similarities to several components of the eukaryotic replication, transcription and translation systems. Emphasis of our research is on the study of transcription and post-transcriptional processing of transfer RNAs (tRNAs) in the halophilic and thermophilic archaea. Transcriptional promoters in archaea, are somewhat similar to the eukaryotic promoters, especially to the RNA polymerase II promoters. Splicing of introns in archaeal tRNAs is protein-enzyme based, involving at least an endonuclease and a ligase. This is also the case for the splicing of tRNA-introns in the eukaryotes. There are two different mechanisms of the litigation of fRNA exons in the eukaryotes; an animal type and a yeast type. We have determined that the mechanism of ligation of exons in the archaea shows some similarities to the animal type mechanism. Experience Needed: Some research experience in the area of molecular biology and/or biochemistry is needed. Number of students: 1-2 Willing to serve as an MPEE mentor? Yes Piroska Huvos, Ph.D. Office Location: Neckers, Room 210, Carbondale Phone Office: 618-453-6469 Research Area: Analysis of genome reorganization during evolution and in pathological states Summary: Tetrahymena, a ciliated protozoan that undergoes extensive programmed genome deletions during development, is used as a model. We are attempting to identify changes in the DNA that interfere with developmental deletions using comparisons among different strains and species of Tetrahymena. The general experimental strategy starts with exploratory characterization of a region where a developmentally eliminated sequence occurs, to detect possible polymorphisms. If a polymorphism is found in a strain, the DNA fragment of interest is produced on a large scale, usually cloned, and then analyzed by restriction digestion and sequencing. These steps are well suited for introducing students to basic ideas and techniques used in molecular biology. An integral part of the work is the analysis of these sequences. This includes the assembly and reconciliation of the sequence, and its comparison with existing data using web tools. In addition, students can spend some time on literature and data base searches on DNA rearrangements in human disease. Possible areas for the searches are the occurrence of small deletions in malignances. Experience Needed: Some experience in a molecular biology or microbiology laboratory. Previous experience is not absolutely essential, especially if the person would like to be introduced to general concepts and methodology used in molecular biology. Number of Students: max 2 Willing to serve as an MPEE mentor? Yes Eric C. Niederhoffer, Ph.D. Office Location: Lindegren Hall, Room 112, Carbondale Laboratory Location: Lindegren Hall, Room 112, Carbondale Phone Office: 618-453-6467 Research Focus: Metallobiology: Structure and Function of Metal Ion Containing Macromolecules eniederhoffer@siumed.edu Research Area: Metallobiology Summary: Medical students will receive training in metallobiology and will use a variety of applications to prepare internet-based resources. Experience Needed: Computer experience would be useful. Motivation to learn is more important. Number of Students: 2 Willing to serve as an MPEE mentor? Yes
Blaine Bartholomew, Ph.D. Office Location: Neckers Building, Room 211, Carbondale Laboratory Location: Neckers Building, Room 202 or 207, Carbondale Phone Office: 618-453-6437 Laboratory: 618-453-6436 or 618-453-1132 Research Focus: Gene Regulation, Chromatin Willing to serve as an MPEE mentor? Yes
Ramesh Gupta, Ph.D. Office Location: Neckers, Room 210, Carbondale Laboratory Location: Neckers, Room 206, Carbondale Phone Office: 618-453-6466 Lab: 618-453-6493 Research Focus: Molecular Biology of Archaea (Archaebacteria), Transcription, RNA Processing rgupta@siumed.edu
Research Area: Molecular biology of archaea Summary: Our research interests are mainly in the area of gene regulation in archaea (archaebacteria). Archaea are one of the three domains of life; the other two being Bacteria (eubacteria) and Eukarya (eukaryotes). Archaea include methanogens (producing methane), extreme halophiles (growing in two molar to nearly saturated salt concentrations), thermophiles and hyperthermophiles (growing at 65 to 106 degrees C), acidophiles, alkaliphiles, etc. Archaea, like Bacteria, are prokaryotic in organization, but show similarities to several components of the eukaryotic replication, transcription and translation systems.
Emphasis of our research is on the study of transcription and post-transcriptional processing of transfer RNAs (tRNAs) in the halophilic and thermophilic archaea. Transcriptional promoters in archaea, are somewhat similar to the eukaryotic promoters, especially to the RNA polymerase II promoters. Splicing of introns in archaeal tRNAs is protein-enzyme based, involving at least an endonuclease and a ligase. This is also the case for the splicing of tRNA-introns in the eukaryotes. There are two different mechanisms of the litigation of fRNA exons in the eukaryotes; an animal type and a yeast type. We have determined that the mechanism of ligation of exons in the archaea shows some similarities to the animal type mechanism. Experience Needed: Some research experience in the area of molecular biology and/or biochemistry is needed. Number of students: 1-2 Willing to serve as an MPEE mentor? Yes
Piroska Huvos, Ph.D. Office Location: Neckers, Room 210, Carbondale Phone Office: 618-453-6469 Research Area: Analysis of genome reorganization during evolution and in pathological states
Summary: Tetrahymena, a ciliated protozoan that undergoes extensive programmed genome deletions during development, is used as a model. We are attempting to identify changes in the DNA that interfere with developmental deletions using comparisons among different strains and species of Tetrahymena.
The general experimental strategy starts with exploratory characterization of a region where a developmentally eliminated sequence occurs, to detect possible polymorphisms. If a polymorphism is found in a strain, the DNA fragment of interest is produced on a large scale, usually cloned, and then analyzed by restriction digestion and sequencing. These steps are well suited for introducing students to basic ideas and techniques used in molecular biology. An integral part of the work is the analysis of these sequences. This includes the assembly and reconciliation of the sequence, and its comparison with existing data using web tools.
In addition, students can spend some time on literature and data base searches on DNA rearrangements in human disease. Possible areas for the searches are the occurrence of small deletions in malignances.
Experience Needed: Some experience in a molecular biology or microbiology laboratory. Previous experience is not absolutely essential, especially if the person would like to be introduced to general concepts and methodology used in molecular biology.
Number of Students: max 2 Willing to serve as an MPEE mentor? Yes
Eric C. Niederhoffer, Ph.D. Office Location: Lindegren Hall, Room 112, Carbondale Laboratory Location: Lindegren Hall, Room 112, Carbondale Phone Office: 618-453-6467 Research Focus: Metallobiology: Structure and Function of Metal Ion Containing Macromolecules eniederhoffer@siumed.edu
Research Area: Metallobiology Summary: Medical students will receive training in metallobiology and will use a variety of applications to prepare internet-based resources.
Experience Needed: Computer experience would be useful. Motivation to learn is more important. Number of Students: 2 Willing to serve as an MPEE mentor? Yes
J. M. Craig, Ph.D. Office Location: Clinical Ethics Center - Memorial Medical Center 200 W. Dodge - Room Medical Arts Building 222, Springfield Laboratory Location: Clinical Ethics Center - Memorial Medical Center 200 W. Dodge - Room Medical Arts Building 222, Springfield Phone Office: 217-757-2353 Laboratory: 217-757-2353 Research Focus: Ethical Issues in Medicine, Bio-science or Public Health. Research needs will depend on current center projects. jcraig@siumed.edu Experience Needed: Computer experience would be useful. Motivation to learn is more important. Willing to serve as an MPEE mentor? Yes
J. M. Craig, Ph.D. Office Location: Clinical Ethics Center - Memorial Medical Center 200 W. Dodge - Room Medical Arts Building 222, Springfield Laboratory Location: Clinical Ethics Center - Memorial Medical Center 200 W. Dodge - Room Medical Arts Building 222, Springfield Phone Office: 217-757-2353 Laboratory: 217-757-2353 Research Focus: Ethical Issues in Medicine, Bio-science or Public Health. Research needs will depend on current center projects. jcraig@siumed.edu
Experience Needed: Computer experience would be useful. Motivation to learn is more important. Willing to serve as an MPEE mentor? Yes
Lisabeth DiLalla, Ph.D. Office Location: Lindegren Hall, Room 210, Carbondale Laboratory Location: Life Science II, Room 224 and 243, Carbondale Phone Office: 618-453-1855 Laboratory: 618-453-5206 and 618-453-1397 Research Focus: Child Development, Early Aggression, Behavior Genetics ldilalla@siumed.edu Research Area: Behavioral genetic analyses of infant and preschool twins' behaviors Summary: Videotaped behavioral data are available for analysis. The data include infant/mother interactions and 5-year-old peer play interactions. The use of twins allows estimation of genetic and environmental influences on the ways that children behave. A research project could entail behavioral coding of the videotaped behaviors or use of already-coded behaviors. Behaviors that might be of interest to study include but are not limited to: mother-infant interaction, maternal teaching styles, peer aggressive play, peer cooperative play, peer compliance or noncompliance. Experience Needed: Statistics course or experience working with a statistical package such as SPSS. Number of Students: 1-2 Willing to serve as an MPEE mentor? Yes Robert Ewart, M.D. Office Location: 520 N. 4th, Springfield Phone Office: 217-757-8137 Research Focus: Screening Tests Willing to serve as an MPEE mentor? Yes Wiley D. Jenkins, Ph.D., MPH. Office Location: 913 N. Rutledge St., Room 1025, Springfield Phone Office: 217-545-8717 Research Focus: Maternal Smoking Cessation; Maternal/Child Health Analyses; Public and Population Health wjenkins@siumed.edu Research Area: Public health Summary: Medical students have different options in which to receive experience. The state’s Department of Healthcare and Family Services (DHFS) is interested in analyzing their extensive database for various health trends and effective practices. Dr. Jenkins is involved in researching community-level STD interventions. Other projects may be developed in accordance with the student’s interest and talents. Experience Needed: Familiarity with basic biostatistical terms and methods and public health principles. Number of Students: 2-4 Willing to serve as an MPEE mentor? Yes Sandra L. Shea, Ph.D. Office Location: Lindegren 111, Carbondale Phone Office: 618-453-1589 Research Focus: Women's College Major and Cancer Choices in Science, Technology, Engineering & Mathematics Willing to serve as an MPEE mentor? Yes Kyaw Naing, M.D., Ph.D. Office Location: 305 W. Jackson, Carbondale Phone Office: 618-536-6621 Research Focus: Behavioral Science, Health Education, Public Health Department: Family and Community Medicine Office: 201 West Jackson St., Carbondale knaing@siumed.edu Research Area: Public health Summary: Research in the public health arena especially dealing with the behavioral and psychosocial aspects of health promotion Number of Students: 2 Willing to serve as an MPEE mentor? Yes
Lisabeth DiLalla, Ph.D. Office Location: Lindegren Hall, Room 210, Carbondale Laboratory Location: Life Science II, Room 224 and 243, Carbondale Phone Office: 618-453-1855 Laboratory: 618-453-5206 and 618-453-1397 Research Focus: Child Development, Early Aggression, Behavior Genetics ldilalla@siumed.edu
Research Area: Behavioral genetic analyses of infant and preschool twins' behaviors Summary: Videotaped behavioral data are available for analysis. The data include infant/mother interactions and 5-year-old peer play interactions. The use of twins allows estimation of genetic and environmental influences on the ways that children behave. A research project could entail behavioral coding of the videotaped behaviors or use of already-coded behaviors. Behaviors that might be of interest to study include but are not limited to: mother-infant interaction, maternal teaching styles, peer aggressive play, peer cooperative play, peer compliance or noncompliance. Experience Needed: Statistics course or experience working with a statistical package such as SPSS. Number of Students: 1-2 Willing to serve as an MPEE mentor? Yes
Robert Ewart, M.D. Office Location: 520 N. 4th, Springfield Phone Office: 217-757-8137 Research Focus: Screening Tests Willing to serve as an MPEE mentor? Yes
Wiley D. Jenkins, Ph.D., MPH. Office Location: 913 N. Rutledge St., Room 1025, Springfield Phone Office: 217-545-8717 Research Focus: Maternal Smoking Cessation; Maternal/Child Health Analyses; Public and Population Health wjenkins@siumed.edu
Research Area: Public health Summary: Medical students have different options in which to receive experience. The state’s Department of Healthcare and Family Services (DHFS) is interested in analyzing their extensive database for various health trends and effective practices. Dr. Jenkins is involved in researching community-level STD interventions. Other projects may be developed in accordance with the student’s interest and talents. Experience Needed: Familiarity with basic biostatistical terms and methods and public health principles. Number of Students: 2-4 Willing to serve as an MPEE mentor? Yes
Sandra L. Shea, Ph.D. Office Location: Lindegren 111, Carbondale Phone Office: 618-453-1589 Research Focus: Women's College Major and Cancer Choices in Science, Technology, Engineering & Mathematics Willing to serve as an MPEE mentor? Yes
Kyaw Naing, M.D., Ph.D. Office Location: 305 W. Jackson, Carbondale Phone Office: 618-536-6621 Research Focus: Behavioral Science, Health Education, Public Health Department: Family and Community Medicine Office: 201 West Jackson St., Carbondale knaing@siumed.edu
Research Area: Public health Summary: Research in the public health arena especially dealing with the behavioral and psychosocial aspects of health promotion Number of Students: 2 Willing to serve as an MPEE mentor? Yes
M. Haitham Bakir, M.D., FLLP Office Location: 701 N. 1st, Room D434, Springfield Phone Office: 217-545-0187 Research Focus: Asthma Willing to serve as an MPEE mentor? Yes Kathy Bottum, M.D., Ph.D. Office Location: Memorial Medical Center, Room 492A, Springfield Laboratory Location: 801 North Rutledge, Room 3354, Springfield Phone Office: 217-545-4234 Laboratory: 217-545-6556 Research Focus: Mechanisms of Protection from Excitotoxicity in Suprachiasmatic Nucleus Neurons kbottum@siumed.edu Research Area: Neuroscience Summary: Molecular biology techniques will be used in cell culture to explore important genes and proteins involved in providing protection from excitotoxicity in neurons. Experience Needed: No experience required. Number of Students: 2 Willing to serve as an MPEE mentor? Yes Mark Francis, M.D. Office Location: Memorial Medical Center, D424, Springfield Laboratory Location: Springfield Combined Laboratory Facility Phone Office: 217-545-0184 Laboratory: 217-545-0184 Research Focus: Interactions Between HIV and IFN-a in Monocytes, ß Cell Activation, Immunologic Aspects of Most Any Medical Problem Willing to serve as an MPEE mentor? Yes Maureen Francis, M.D. Office Location: MMC - D417, Springfield Phone Office: 217-545-0170 Research Focus: Project Looking at the Role of CXR in Outpatient Community Acquired Pneumonia, Warfarin Use in Chronic A Fib Willing to serve as an MPEE mentor? Yes Stuart Frank, M.D. Office Location: Memorial Medical Center, D402, Springfield Phone Office: 217-545-0185 Research Focus: Lipid Abnormalities, Electrocardiography Willing to serve as an MPEE mentor? Yes Janak Koirala, M.D., M.P.H., FACP Office Location: Department of Medicine, Division of Infectious Diseases, Memorial Medical Center Building (701 N. First Street), Room A-486, Springfield Laboratory Location: Room 2522, SCLF, 801 N. Rutledge, Springfield Phone Office: 217-545-0181 Laboratory: 217-545-6441, 545-9491 (research coordinator) Research Focus: Immune Reconstitution in HIV Patient (lab), Clinical Research Related to HIV, HCV, Traveler's Health jkoirala@siumed.edu Research Area: Infectious diseases Summary: Medical students will receive training in the area of infectious disease and/or epidemiology research. Experience Needed: A desire to learn. Number of Students: 2 Willing to serve as an MPEE mentor? Yes Nancy Khardori, M.D., F.A.C.P. Office Location: Memorial Medical Center, A4-78, Springfield Laboratory Location: Springfield Combined Laboratory Facility Phone Office: 217-545-0181 Laboratory: 217-545-7801 Research Focus: Adherence of Bacteria and Fungi to Prosthetic Devices; In Vitro and In Vivo Activity of New Antibacterial and Antifungal Agents Willing to serve as an MPEE mentor? Yes Romesh Khardori, M.B., M.D. Office Location: 800 North Rutledge, Room D-4, Springfield Phone Office: 217-545-0166 Research Focus: Neuroendocrinology/Growth and Developmental Disorders Willing to serve as an MPEE mentor? Yes Sherry Robinson, Ph.D., RNCS Office Location: Memorial Medical Center, D417, Springfield Phone Office: 217-545-5559 Research Focus: Nursing Home Care, Maintenance of Functional Status in the Elderly Willing to serve as an MPEE mentor? Yes Laura Q. Rogers, M.D., M.P.H. Office Location: Memorial Medical Center, Room C405, Springfield Phone Office: 217-545-7980 Research Focus: Exercise and/or Physical Activity Effects, Behavior, Measurement and Promotion Among Chronic Disease Patients (with an emphasis on cancer, arthritis, and obesity) lrogers@siumed.edu Research Area: Exercise and physical activity Summary: Depending on projects in progress at the time of the experience, students will obtain training in some component of the following related to chronic disease patients: understanding exercise determinants, promoting exercise adherence, measuring physical activity, and assessing physical activity biopsychosocial effects. The student may also gain experience in survey design/administration (clinic and population-based) and data management/analysis. Experience Needed: Computer experience is required. A genuine interest in the topic is essential. Number of Students: 1 Willing to serve as an MPEE mentor? Yes
M. Haitham Bakir, M.D., FLLP Office Location: 701 N. 1st, Room D434, Springfield Phone Office: 217-545-0187 Research Focus: Asthma Willing to serve as an MPEE mentor? Yes
Kathy Bottum, M.D., Ph.D. Office Location: Memorial Medical Center, Room 492A, Springfield Laboratory Location: 801 North Rutledge, Room 3354, Springfield Phone Office: 217-545-4234 Laboratory: 217-545-6556 Research Focus: Mechanisms of Protection from Excitotoxicity in Suprachiasmatic Nucleus Neurons kbottum@siumed.edu
Research Area: Neuroscience Summary: Molecular biology techniques will be used in cell culture to explore important genes and proteins involved in providing protection from excitotoxicity in neurons.
Experience Needed: No experience required. Number of Students: 2 Willing to serve as an MPEE mentor? Yes
Mark Francis, M.D. Office Location: Memorial Medical Center, D424, Springfield Laboratory Location: Springfield Combined Laboratory Facility Phone Office: 217-545-0184 Laboratory: 217-545-0184 Research Focus: Interactions Between HIV and IFN-a in Monocytes, ß Cell Activation, Immunologic Aspects of Most Any Medical Problem Willing to serve as an MPEE mentor? Yes
Maureen Francis, M.D. Office Location: MMC - D417, Springfield Phone Office: 217-545-0170 Research Focus: Project Looking at the Role of CXR in Outpatient Community Acquired Pneumonia, Warfarin Use in Chronic A Fib Willing to serve as an MPEE mentor? Yes
Stuart Frank, M.D. Office Location: Memorial Medical Center, D402, Springfield Phone Office: 217-545-0185 Research Focus: Lipid Abnormalities, Electrocardiography Willing to serve as an MPEE mentor? Yes
Janak Koirala, M.D., M.P.H., FACP Office Location: Department of Medicine, Division of Infectious Diseases, Memorial Medical Center Building (701 N. First Street), Room A-486, Springfield Laboratory Location: Room 2522, SCLF, 801 N. Rutledge, Springfield Phone Office: 217-545-0181 Laboratory: 217-545-6441, 545-9491 (research coordinator) Research Focus: Immune Reconstitution in HIV Patient (lab), Clinical Research Related to HIV, HCV, Traveler's Health jkoirala@siumed.edu
Research Area: Infectious diseases Summary: Medical students will receive training in the area of infectious disease and/or epidemiology research.
Experience Needed: A desire to learn. Number of Students: 2 Willing to serve as an MPEE mentor? Yes
Nancy Khardori, M.D., F.A.C.P. Office Location: Memorial Medical Center, A4-78, Springfield Laboratory Location: Springfield Combined Laboratory Facility Phone Office: 217-545-0181 Laboratory: 217-545-7801 Research Focus: Adherence of Bacteria and Fungi to Prosthetic Devices; In Vitro and In Vivo Activity of New Antibacterial and Antifungal Agents Willing to serve as an MPEE mentor? Yes
Romesh Khardori, M.B., M.D. Office Location: 800 North Rutledge, Room D-4, Springfield Phone Office: 217-545-0166 Research Focus: Neuroendocrinology/Growth and Developmental Disorders Willing to serve as an MPEE mentor? Yes
Sherry Robinson, Ph.D., RNCS Office Location: Memorial Medical Center, D417, Springfield Phone Office: 217-545-5559 Research Focus: Nursing Home Care, Maintenance of Functional Status in the Elderly Willing to serve as an MPEE mentor? Yes
Laura Q. Rogers, M.D., M.P.H. Office Location: Memorial Medical Center, Room C405, Springfield Phone Office: 217-545-7980 Research Focus: Exercise and/or Physical Activity Effects, Behavior, Measurement and Promotion Among Chronic Disease Patients (with an emphasis on cancer, arthritis, and obesity) lrogers@siumed.edu
Research Area: Exercise and physical activity Summary: Depending on projects in progress at the time of the experience, students will obtain training in some component of the following related to chronic disease patients: understanding exercise determinants, promoting exercise adherence, measuring physical activity, and assessing physical activity biopsychosocial effects. The student may also gain experience in survey design/administration (clinic and population-based) and data management/analysis.
Experience Needed: Computer experience is required. A genuine interest in the topic is essential. Number of Students: 1 Willing to serve as an MPEE mentor? Yes
Ann C. Kelson Office Location: 801 North Rutledge, Room 3153, Springfield Laboratory Location: 801 North Rutledge, Room 3153, Springfield Phone Office: 217-545-9502 Laboratory: 217-545-0795 Research Focus: Problem-Based Learning; Investigating the Effects of Student-Initiated Learning on Motivation, Acquisition of Knowledge, Retention of Knowledge, and Development of Lifelong Learning Skills Willing to serve as an MPEE mentor? Yes Deb Klamen, M.D., MHPE Office Location: 801 N. Rutledge, Rm 3050A, Springfield Laboratory Location: N/A Phone Office: 217-545-7932 Research Focus: Medical Education; Curriculum Development, Assessment of Clinical Performance dklamen@siumed.edu Research Area: Medical education Summary: Medical students will learn about the research being done in medical education and be involved in any of a number of ongoing projects in the area. Experience Needed: Computer skills would be great, but a motivation and interest in the area is most important. Number of Students: 1 Willing to serve as an MPEE mentor? Yes
Ann C. Kelson Office Location: 801 North Rutledge, Room 3153, Springfield Laboratory Location: 801 North Rutledge, Room 3153, Springfield Phone Office: 217-545-9502 Laboratory: 217-545-0795 Research Focus: Problem-Based Learning; Investigating the Effects of Student-Initiated Learning on Motivation, Acquisition of Knowledge, Retention of Knowledge, and Development of Lifelong Learning Skills Willing to serve as an MPEE mentor? Yes
Deb Klamen, M.D., MHPE Office Location: 801 N. Rutledge, Rm 3050A, Springfield Laboratory Location: N/A Phone Office: 217-545-7932 Research Focus: Medical Education; Curriculum Development, Assessment of Clinical Performance dklamen@siumed.edu
Research Area: Medical education Summary: Medical students will learn about the research being done in medical education and be involved in any of a number of ongoing projects in the area.
Experience Needed: Computer skills would be great, but a motivation and interest in the area is most important. Number of Students: 1 Willing to serve as an MPEE mentor? Yes
Peter Borgia, Ph.D. Office Location: 801 North Rutledge, Room 2369, Springfield Laboratory Location: 801 North Rutledge, Room 2345, Springfield Phone Office: 217-545-9435 Laboratory: 217-545-8743 Research Focus: Cell Wall Chitin Synthase by Fungi Willing to serve as an MPEE mentor? Yes Gregory J. Brewer, Ph.D. Office Location: Room 1269, 801 N. Rutledge, Springfield Laboratory Location: Room 1269, 801 N. Rutledge, Springfield Phone Office: 217-545-5230 Laboratory: 217-545-5731 Research Focus: Aging, Alzheimer disease, Neuronal Network Bioengineering (separate), Brain Cancer gbrewer@siumed.edu Research Area: Aging mitochondrial function in neurons in relation to Alzheimer disease; manipulating neuronal networks in 2D and 3D to understand neuronal coding; novel nutritional treatment for brain tumors Summary: Laboratory experiments will be conducted to advance the field in the above areas. Experience Needed: Prior lab experience helpful. Number of Students: 3 (one in each area) Willing to serve as an MPEE mentor? Yes David Carpenter, Ph.D. Office Location: 801 North Rutledge, Room 2381, Springfield Laboratory Location: Springfield Combined Lab Facility, Rooms 2536 Phone Office: 217-545-8465 Laboratory: 217-545-3968 Research Focus: Emerging Infectious Diseases Surveillance/Epidemiology Willing to serve as an MPEE mentor? Yes Morris D. Cooper, Ph.D. Office Location: 801 North Rutledge, Room 2389, Springfield Laboratory Location: Springfield Combined Lab Facility, Rooms 2530 and 2534 Phone Office: 217-545-8462 Laboratory: 217-782-8451 Research Focus: STDs and Mucosal Immunology Willing to serve as an MPEE mentor? Yes Yin-Yuan Mo, Ph.D. Office Location: 911 N. Rutledge Room 1330A, Springfield Laboratory Location: 911 N. Rutledge Room 1315, Springfield Phone Office: 217-545-8508 Laboratory: 217-545-7374 Research Focus: Breast Cancer, Focusing on Alterations of Posttranslational Modifications and Tumorigenesis ymo@siumed.edu Research Area: Molecular biology and tumor cell biology Summary: Students will receive training in basic principles of molecular biology and will learn bench techniques such as gene cloning and expression. Experience Needed: None. Number of Students: 2 Willing to serve as an MPEE mentor? Yes John Martinko, Ph.D. Office Location: Life Science II, Room 131, Carbondale Laboratory Location: Life Science II, Room 127, Carbondale Phone Office: 618-536-2349 Laboratory: 618-453-3721 Research Focus: Diagnostic Tools for Plant pathogens, Immune Response in Growth Hormone Transgenic Animals Willing to serve as an MPEE mentor? Yes Mary Pauza, Ph.D. Office Location: 801 North Rutledge, Room 3385, Springfield Laboratory Location: 801 North Rutledge, Room 3362, Springfield Phone Office: 217-545-4334 Laboratory: 217-545-2217 Research Focus: Immunology and Type I Diabetes mpauza@siumed.edu Research Area: Immune function as it relates to autoimmunity Summary: My lab seeks to understand how type 1 diabetes occurs and to explore novel immune-based prevention strategies. Because autoreactive T cells are central players in pancreas beta cell destruction, we are interested in how T cells find their way to the pancreas as disease develops as well as how we can change their destructive nature. While participating in research in my laboratory students will have the opportunity to work with mouse models of type 1 diabetes (transgenics and knock-outs) and will learn one or more of the following techniques: polymerase chain reaction, genotyping, tissue culture, flow cytometry, blood glucose monitoring, DNA and RNA isolation, RNase protection assays, cell migration assays, cell proliferation assays, ELISA, expression vector construction, gene transfection or transformation, plasmid DNA purification, restriction enzyme digests. Experience Needed: Previous rodent handling, molecular biology skills, sterile tissue culture techniques, or experience with antibody based detection systems would all be viewed as beneficial, however none are required. A desire to learn and discover is essential. Number of Students: 1 Willing to serve as an MPEE mentor? Yes Sophia Ran, Ph.D. Office Location: 911 N. Rutledge St. Room 1310C, Springfield Laboratory Location: 911 N. Rutledge St. Room 1348, Springfield Phone Office: 217-545-7026 Laboratory: 217-545-7332 Research Focus: Formation of the Tumor Blood and Lymphatic Vessels and Their Role in Metastatic Spread of Breast Cancer sran@siumed.edu Research Area: Tumor angiogenesis and lymphangiogenesis Summary: Students will receive training in culturing malignant and endothelial cells in vitro and analyzing factors secreted from these cells that induce angiogenesis in vivo. Experience Needed: Prior experience in a research lab or tissue culture facility is desirable but not absolutely indispensable. Number of Students: 1 Willing to serve as an MPEE mentor? Yes Donald Torry, Ph.D. Office Location: 801 North Rutledge, Room 3333, Springfield Laboratory Location: 801 North Rutledge, Room 3354, Springfield Phone Office: 217-545-2181 Laboratory: 217-545-2216 Research Focus: Cell Biology of Human Placenta, Pregnancy Complications, Angiogenesis dtorry@siumed.edu Research Area: Pregnancy Summary: Student will receive training in molecular and cellular techniques to analyze gene expression and cell function of human placenta in normal and/or pathological conditions of pregnancy. Experience Needed: Prior cell culture experience helpful; student initiative, motivation, and diligence required. Number of Students: 1 Willing to serve as an MPEE mentor? Yes Kounosuke Watabe, Ph.D. Office Location: 801 North Rutledge, Room 2373, Springfield Laboratory Location: 801 North Rutledge, Room 2554, Springfield Phone Laboratory: 217-545-3969 Research Focus: Oncology Pharmacology Willing to serve as an MPEE mentor? Yes
Peter Borgia, Ph.D. Office Location: 801 North Rutledge, Room 2369, Springfield Laboratory Location: 801 North Rutledge, Room 2345, Springfield Phone Office: 217-545-9435 Laboratory: 217-545-8743 Research Focus: Cell Wall Chitin Synthase by Fungi Willing to serve as an MPEE mentor? Yes
Gregory J. Brewer, Ph.D. Office Location: Room 1269, 801 N. Rutledge, Springfield Laboratory Location: Room 1269, 801 N. Rutledge, Springfield Phone Office: 217-545-5230 Laboratory: 217-545-5731 Research Focus: Aging, Alzheimer disease, Neuronal Network Bioengineering (separate), Brain Cancer gbrewer@siumed.edu
David Carpenter, Ph.D. Office Location: 801 North Rutledge, Room 2381, Springfield Laboratory Location: Springfield Combined Lab Facility, Rooms 2536 Phone Office: 217-545-8465 Laboratory: 217-545-3968 Research Focus: Emerging Infectious Diseases Surveillance/Epidemiology Willing to serve as an MPEE mentor? Yes
Morris D. Cooper, Ph.D. Office Location: 801 North Rutledge, Room 2389, Springfield Laboratory Location: Springfield Combined Lab Facility, Rooms 2530 and 2534 Phone Office: 217-545-8462 Laboratory: 217-782-8451 Research Focus: STDs and Mucosal Immunology Willing to serve as an MPEE mentor? Yes
Yin-Yuan Mo, Ph.D. Office Location: 911 N. Rutledge Room 1330A, Springfield Laboratory Location: 911 N. Rutledge Room 1315, Springfield Phone Office: 217-545-8508 Laboratory: 217-545-7374 Research Focus: Breast Cancer, Focusing on Alterations of Posttranslational Modifications and Tumorigenesis ymo@siumed.edu
Research Area: Molecular biology and tumor cell biology Summary: Students will receive training in basic principles of molecular biology and will learn bench techniques such as gene cloning and expression.
Experience Needed: None. Number of Students: 2 Willing to serve as an MPEE mentor? Yes
John Martinko, Ph.D. Office Location: Life Science II, Room 131, Carbondale Laboratory Location: Life Science II, Room 127, Carbondale Phone Office: 618-536-2349 Laboratory: 618-453-3721 Research Focus: Diagnostic Tools for Plant pathogens, Immune Response in Growth Hormone Transgenic Animals Willing to serve as an MPEE mentor? Yes
Mary Pauza, Ph.D. Office Location: 801 North Rutledge, Room 3385, Springfield Laboratory Location: 801 North Rutledge, Room 3362, Springfield Phone Office: 217-545-4334 Laboratory: 217-545-2217 Research Focus: Immunology and Type I Diabetes mpauza@siumed.edu
Research Area: Immune function as it relates to autoimmunity Summary: My lab seeks to understand how type 1 diabetes occurs and to explore novel immune-based prevention strategies. Because autoreactive T cells are central players in pancreas beta cell destruction, we are interested in how T cells find their way to the pancreas as disease develops as well as how we can change their destructive nature. While participating in research in my laboratory students will have the opportunity to work with mouse models of type 1 diabetes (transgenics and knock-outs) and will learn one or more of the following techniques: polymerase chain reaction, genotyping, tissue culture, flow cytometry, blood glucose monitoring, DNA and RNA isolation, RNase protection assays, cell migration assays, cell proliferation assays, ELISA, expression vector construction, gene transfection or transformation, plasmid DNA purification, restriction enzyme digests.
Experience Needed: Previous rodent handling, molecular biology skills, sterile tissue culture techniques, or experience with antibody based detection systems would all be viewed as beneficial, however none are required. A desire to learn and discover is essential. Number of Students: 1 Willing to serve as an MPEE mentor? Yes
Sophia Ran, Ph.D. Office Location: 911 N. Rutledge St. Room 1310C, Springfield Laboratory Location: 911 N. Rutledge St. Room 1348, Springfield Phone Office: 217-545-7026 Laboratory: 217-545-7332 Research Focus: Formation of the Tumor Blood and Lymphatic Vessels and Their Role in Metastatic Spread of Breast Cancer sran@siumed.edu
Research Area: Tumor angiogenesis and lymphangiogenesis Summary: Students will receive training in culturing malignant and endothelial cells in vitro and analyzing factors secreted from these cells that induce angiogenesis in vivo.
Experience Needed: Prior experience in a research lab or tissue culture facility is desirable but not absolutely indispensable. Number of Students: 1 Willing to serve as an MPEE mentor? Yes
Donald Torry, Ph.D. Office Location: 801 North Rutledge, Room 3333, Springfield Laboratory Location: 801 North Rutledge, Room 3354, Springfield Phone Office: 217-545-2181 Laboratory: 217-545-2216 Research Focus: Cell Biology of Human Placenta, Pregnancy Complications, Angiogenesis dtorry@siumed.edu
Research Area: Pregnancy Summary: Student will receive training in molecular and cellular techniques to analyze gene expression and cell function of human placenta in normal and/or pathological conditions of pregnancy.
Experience Needed: Prior cell culture experience helpful; student initiative, motivation, and diligence required. Number of Students: 1 Willing to serve as an MPEE mentor? Yes
Kounosuke Watabe, Ph.D. Office Location: 801 North Rutledge, Room 2373, Springfield Laboratory Location: 801 North Rutledge, Room 2554, Springfield Phone Laboratory: 217-545-3969 Research Focus: Oncology Pharmacology Willing to serve as an MPEE mentor? Yes
K. Harirama Acharya, M.D. Office Location: MMC, Springfield Phone: 217-545-5175 Research Focus: None Willing to serve as an MPEE mentor? Yes Tom Ala, M.D. Office Location: 751 N. Rutledge, Suite 3100, Springfield Laboratory Location: Memory & Aging Clinic, 751 Rutledge St., Springfield Phone Office: 217-545-7200 Laboratory: 217-545-7200 Research Focus: Alzheimer Disease and Other Forms of Dementia tala@siumed.edu Research Area: Clinical research into all aspects of Alzheimer disease Summary: Clinical-neuropathological research using cases from the SIU Alzheimer Center brain bank. The objective will be for the student to design, implement, and write up a study for publication in a scientific journal. Student initiative, motivation, and diligence will be necessary. Research focus to be decided by the student. Experience Needed: None. Number of Students: 1 Willing to serve as an MPEE mentor? Yes Gregory J. Brewer, Ph.D. Office Location: Room 1269, 801 N. Rutledge, Springfield Laboratory Location: Room 1269, 801 N. Rutledge, Springfield Phone Office: 217-545-5230 Laboratory: 217-545-5731 Research Focus: Aging, Alzheimer Disease, Neuronal Network Bioengineering (separate), Brain Cancer gbrewer@siumed.edu Research Area: Aging mitochondrial function in neurons in relation to Alzheimer disease; manipulating neuronal networks in 2D and 3D to understand neuronal coding; novel nutritional treatment for brain tumors Summary: Laboratory experiments will be conducted to advance the field in the above areas. Experience Needed: Prior lab experience helpful. Number of Students: 3 (one in each area) Willing to serve as an MPEE mentor? Yes Rodger J. Elble, M.D., Ph.D. Office Location: 751 N. Rutledge, Room 3100, Springfield Laboratory Location: 801 N. Rutledge, Room 4329, Springfield Phone Office: 217-545-7182 (Brenda, Dr. Elble's secy) Laboratory: 217-545-0895 Research Focus: Movement Disorders and Motor Control with Special Emphasis on Tremor and Gait Disorders. Dementia Willing to serve as an MPEE mentor? Yes M. Steven Evans, M.D. Office Location: 800 North Rutledge, Room C402, Springfield Laboratory Location: 801 North Rutledge, Room 461, Springfield Phone Office: 217-545-5175 Laboratory: 217-545-2714 Research Focus: Long-term Potentiation, Epilepsy, Aging in the CNS Willing to serve as an MPEE mentor? Yes Larry Hughes, Ph.D. Office Location: 751 North Rutledge, Room 3107, Springfield Laboratory Location: 751 North Rutledge, Room 3106 Springfield 801 North Rutledge, Room 1330, Springfield Phone Office: 217-545-7186 Laboratory: 217-545-7186 Research Focus: Aging, Neurodegenerative Diseases, Psychophysics and Statistics Willing to serve as an MPEE mentor? Yes Dean K. Naritoku, M.D. Office Location: Memorial Medical Center, C402, Springfield Laboratory Location: 801 North Rutledge, Room 3247, Springfield Phone Office: 217-545-5175 Laboratory: 217-545-5818 Research Focus: Clinical Drug Trials; Epilepsy Laboratory(Neuropharmacology; Mechanisms of Anticonvulsants Willing to serve as an MPEE mentor? Yes Michael R. Pranzatelli, M.D. Office Location: 751 North Rutledge, Room 3402, Springfield Laboratory Location: 801 Building, Room 2359, Springfield Phone Office: 217-545-7635 Laboratory: 217-545-6523 Research Focus: Basis of Childhood Autoimmune Neurological Disorders, Especially in Association with Neuroblastoma mpranzatelli@siumed.edu Research Area: Neuroimmunology Summary: We have identified B-cell and T-cell subset abnormalities in cerebrospinal fluid as biomarkers of disease activity. These data are used in clinical drug trials of innovative selective immunotherapy. Visit our website: www.omsusa.org. Experience Needed: Computer experience. For lab project, prior research experience preferred. Number of Students: 1 Willing to serve as an MPEE mentor? Yes Sharon Anderson Renier, MPH Office Location: Memorial Medical Center, Room 402, Springfield Phone Office: 217-545-4295 Research Focus: Epidemiology, Public Health, Chronic Disease Surveillance Willing to serve as an MPEE mentor? Yes Robert G. Struble, Ph.D. Office Location: 801 North Rutledge, Room 4373, Springfield Laboratory Location: 801 North Rutledge, Room 4373, Springfield Phone Office: 217-545-4429 Laboratory: 217-545-4429 Research Focus: Alzheimer,s Disease; Regeneration of the Nervous System Willing to serve as an MPEE mentor? Yes
K. Harirama Acharya, M.D. Office Location: MMC, Springfield Phone: 217-545-5175 Research Focus: None Willing to serve as an MPEE mentor? Yes
Tom Ala, M.D. Office Location: 751 N. Rutledge, Suite 3100, Springfield Laboratory Location: Memory & Aging Clinic, 751 Rutledge St., Springfield Phone Office: 217-545-7200 Laboratory: 217-545-7200 Research Focus: Alzheimer Disease and Other Forms of Dementia tala@siumed.edu
Research Area: Clinical research into all aspects of Alzheimer disease Summary: Clinical-neuropathological research using cases from the SIU Alzheimer Center brain bank. The objective will be for the student to design, implement, and write up a study for publication in a scientific journal. Student initiative, motivation, and diligence will be necessary. Research focus to be decided by the student.
Experience Needed: None. Number of Students: 1 Willing to serve as an MPEE mentor? Yes
Rodger J. Elble, M.D., Ph.D. Office Location: 751 N. Rutledge, Room 3100, Springfield Laboratory Location: 801 N. Rutledge, Room 4329, Springfield Phone Office: 217-545-7182 (Brenda, Dr. Elble's secy) Laboratory: 217-545-0895 Research Focus: Movement Disorders and Motor Control with Special Emphasis on Tremor and Gait Disorders. Dementia Willing to serve as an MPEE mentor? Yes
M. Steven Evans, M.D. Office Location: 800 North Rutledge, Room C402, Springfield Laboratory Location: 801 North Rutledge, Room 461, Springfield Phone Office: 217-545-5175 Laboratory: 217-545-2714 Research Focus: Long-term Potentiation, Epilepsy, Aging in the CNS Willing to serve as an MPEE mentor? Yes
Larry Hughes, Ph.D. Office Location: 751 North Rutledge, Room 3107, Springfield Laboratory Location: 751 North Rutledge, Room 3106 Springfield 801 North Rutledge, Room 1330, Springfield Phone Office: 217-545-7186 Laboratory: 217-545-7186 Research Focus: Aging, Neurodegenerative Diseases, Psychophysics and Statistics Willing to serve as an MPEE mentor? Yes
Dean K. Naritoku, M.D. Office Location: Memorial Medical Center, C402, Springfield Laboratory Location: 801 North Rutledge, Room 3247, Springfield Phone Office: 217-545-5175 Laboratory: 217-545-5818 Research Focus: Clinical Drug Trials; Epilepsy Laboratory(Neuropharmacology; Mechanisms of Anticonvulsants Willing to serve as an MPEE mentor? Yes
Michael R. Pranzatelli, M.D. Office Location: 751 North Rutledge, Room 3402, Springfield Laboratory Location: 801 Building, Room 2359, Springfield Phone Office: 217-545-7635 Laboratory: 217-545-6523 Research Focus: Basis of Childhood Autoimmune Neurological Disorders, Especially in Association with Neuroblastoma mpranzatelli@siumed.edu
Research Area: Neuroimmunology Summary: We have identified B-cell and T-cell subset abnormalities in cerebrospinal fluid as biomarkers of disease activity. These data are used in clinical drug trials of innovative selective immunotherapy. Visit our website: www.omsusa.org.
Experience Needed: Computer experience. For lab project, prior research experience preferred. Number of Students: 1 Willing to serve as an MPEE mentor? Yes
Sharon Anderson Renier, MPH Office Location: Memorial Medical Center, Room 402, Springfield Phone Office: 217-545-4295 Research Focus: Epidemiology, Public Health, Chronic Disease Surveillance Willing to serve as an MPEE mentor? Yes
Robert G. Struble, Ph.D. Office Location: 801 North Rutledge, Room 4373, Springfield Laboratory Location: 801 North Rutledge, Room 4373, Springfield Phone Office: 217-545-4429 Laboratory: 217-545-4429 Research Focus: Alzheimer,s Disease; Regeneration of the Nervous System Willing to serve as an MPEE mentor? Yes
Carol Bauer, M.D. Office Location: St. John's Pavilion, Springfield Laboratory Location: 801 North Rutledge, Springfield Phone Office: 217-545-4777 Laboratory: 217-545-6583 Research Focus: Tinnitus Willing to serve as an MPEE mentor? Yes
Mary McAsey, Ph.D. Office Location: 9113 North Rutledge, Room 1325, Springfield Laboratory Location: 911 North Rutledge, Room 329, Springfield Phone Office: 217-545-4692 Laboratory: 217-545-2173 Research Focus: The Role of Estrogen in Neuroprotection and Repair, Disorders of Pregnancy, Gynecologic Cancer, Stem Cell Biology Willing to serve as an MPEE mentor? Yes Victoria Nichols-Johnson, M.D. Office Location: Memorial Medical Center, Room 220, Springfield Phone Office: 217-545-8882 Research Focus: Lactation, Contraception Willing to serve as an MPEE mentor? Yes
Mary McAsey, Ph.D. Office Location: 9113 North Rutledge, Room 1325, Springfield Laboratory Location: 911 North Rutledge, Room 329, Springfield Phone Office: 217-545-4692 Laboratory: 217-545-2173 Research Focus: The Role of Estrogen in Neuroprotection and Repair, Disorders of Pregnancy, Gynecologic Cancer, Stem Cell Biology Willing to serve as an MPEE mentor? Yes
Victoria Nichols-Johnson, M.D. Office Location: Memorial Medical Center, Room 220, Springfield Phone Office: 217-545-8882 Research Focus: Lactation, Contraception Willing to serve as an MPEE mentor? Yes
Glen P. Aylward, Ph.D. Office Location: St. John's Pavilion, 1025 S. 7th, Springfield Phone Office: 217-545-2618 Research Focus: Developmental Assessment; High Risk Infants, Attention and Learning Disorders Willing to serve as an MPEE mentor? Yes Mark Fishbein, M.D. Office Location: St. John's Pavilion, 3rd Floor, Springfield Phone Office: 217-545-8460 Research Focus: Recurrent Abdominal Pain; Enzyme Assay Willing to serve as an MPEE mentor? Yes Margaret Kovach, Ph.D. Office Location: 801 North Rutledge, Room 2375, Springfield Laboratory Location: 801 North Rutledge, Room 2375, Springfield Phone Office: 217-545-0060 Research Focus: Human Genetics Willing to serve as an MPEE mentor? Yes Michael Schneider, M.D. Office Location: St. John's Pavilion, 301 North 8th Street, 3rd Floor, Springfield Lab Location: 911 North Rutledge, Room 310, Springfield Phone Office: 217-545-4839 Lab: 217-545-2248 Research Focus: Role of DNASE Deficiency and of Specific DNASE Alelles in the Pathogenesis of Systemic Lupus Erythematosus (SLE) and as Barriers to Liposomal Gene Transfection mschneider@siumed.edu Research Area: Human genetics/autoimmunity/gene therapy Summary: Laboratory projects: I have a circumscribed project involving genotyping of a small group of samples. This would require no prior experience, and would entail amplification, and sequencing of a specific gene. For those who have some lab experience, I have tissue culture experiments studying the role of DNASEs as barriers to liposomal transfection. Clinical reports: We have interest in reporting a number of atypical or well-phenotyped or novel genotypes for a number of cases. Finally, we have access to clinical parameters of a large phenotyped population, correlational analysis of the data could be performed with some preliminary preparation. Experience Needed: Enthusiasm can trump experience; however, absent laboratory training, refreshing about the following techniques are would be helpful. Clinical studies could always be done without prior experience, or time commitment in an office or lab. Number of Students: 2 Willing to serve as an MPEE mentor? Yes
Glen P. Aylward, Ph.D. Office Location: St. John's Pavilion, 1025 S. 7th, Springfield Phone Office: 217-545-2618 Research Focus: Developmental Assessment; High Risk Infants, Attention and Learning Disorders Willing to serve as an MPEE mentor? Yes
Mark Fishbein, M.D. Office Location: St. John's Pavilion, 3rd Floor, Springfield Phone Office: 217-545-8460 Research Focus: Recurrent Abdominal Pain; Enzyme Assay Willing to serve as an MPEE mentor? Yes
Margaret Kovach, Ph.D. Office Location: 801 North Rutledge, Room 2375, Springfield Laboratory Location: 801 North Rutledge, Room 2375, Springfield Phone Office: 217-545-0060 Research Focus: Human Genetics Willing to serve as an MPEE mentor? Yes
Michael Schneider, M.D. Office Location: St. John's Pavilion, 301 North 8th Street, 3rd Floor, Springfield Lab Location: 911 North Rutledge, Room 310, Springfield Phone Office: 217-545-4839 Lab: 217-545-2248 Research Focus: Role of DNASE Deficiency and of Specific DNASE Alelles in the Pathogenesis of Systemic Lupus Erythematosus (SLE) and as Barriers to Liposomal Gene Transfection mschneider@siumed.edu
Research Area: Human genetics/autoimmunity/gene therapy Summary:
Laboratory projects: I have a circumscribed project involving genotyping of a small group of samples. This would require no prior experience, and would entail amplification, and sequencing of a specific gene. For those who have some lab experience, I have tissue culture experiments studying the role of DNASEs as barriers to liposomal transfection.
Clinical reports: We have interest in reporting a number of atypical or well-phenotyped or novel genotypes for a number of cases. Finally, we have access to clinical parameters of a large phenotyped population, correlational analysis of the data could be performed with some preliminary preparation.
Experience Needed: Enthusiasm can trump experience; however, absent laboratory training, refreshing about the following techniques are would be helpful. Clinical studies could always be done without prior experience, or time commitment in an office or lab. Number of Students: 2 Willing to serve as an MPEE mentor? Yes
Amy Arai, Ph.D. Office Location: 801 North Rutledge, Room 3321, Springfield Laboratory Location: 801 North Rutledge, Room 3275, Springfield Phone Office: 217-545-0228 Laboratory: 217-545-2204 Research Focus: Neuropharmacology Willing to serve as an MPEE mentor? Yes Don Caspary, Ph.D. Office Location: 801 North Rutledge, Room 3265, Springfield Laboratory Location: 801 North Rutledge, Room 3234, Springfield Phone Office: 217-545-2195 Laboratory: 217-545-2203 Research Focus: Aging in Sensory Systems Willing to serve as an MPEE mentor? Yes George Dunaway, Ph.D. Office Location: 801 North Rutledge, Room 3329, Springfield Laboratory Location: 801 North Rutledge, Room 3379, Springfield Phone Office: 217-545-2182 Laboratory: 217-545-2218 Research Focus: Role of Cell Division and Cell Death in Development and Loss of Hearing Willing to serve as an MPEE mentor? Yes Carl Faingold, Ph.D. Office Location: 801 North Rutledge, Room 3289, Springfield Laboratory Location: 801 North Rutledge, Room 3246, Springfield Phone Office: 217-545-2185 Laboratory: 217-545-2206 Research Focus: Investigating Drug Actions on the Brain cfaingold@siumed.edu Research Area: Epilepsy Summary: This research activity involves the study of how drugs act on the brain to depress or excite the nervous system, involved in epilepsy. Drugs are injected systemically or focally within the brain and neuronal firing and behavior changes are examined. The student will be involved in observation and analysis of the resulting data and analysis of brain slices for locations using histology. Experience Needed: Previous histological experience would be helpful. Number of Students: 2 Willing to serve as an MPEE mentor? Yes Tony Lee, Ph.D. Office Location: 801 North Rutledge, Room 3317, Springfield Laboratory Location: 801 North Rutledge, Room 3219 and 3346, Springfield Phone Office: 217-545-2197 Laboratory: 217-545-2215 Research Focus: Septic Shock, Cerebral Blood Vessel Pharmacology Willing to serve as an MPEE mentor? Yes Dean K. Naritoku, M.D. Office Location: Memorial Medical Center, C402, Springfield Laboratory Location: 801 North Rutledge, Room 3247, Springfield Phone Office: 217-545-5175 Laboratory: 217-545-5818 Research Focus: Clinical Drug Trials; Epilepsy Laboratory-Neuropharmacology; Mechanisms of Anticonvulsants Willing to serve as an MPEE mentor? Yes Louis Premkumar, Ph.D. Office Location: 801 North Rutledge, Room 3341, Springfield Laboratory Location: 801 North Rutledge, Springfield Phone Office: 217-545-2179 Research Focus: Ion Channels Involved in Memory Formation and Pain Perception Willing to serve as an MPEE mentor? Yes Vickram Ramkumar, Ph.D. Office Location: 801 North Rutledge, Room 3337, Springfield Laboratory Location: 801 North Rutledge, Room 3338, Springfield Phone Office: 217-545-2171 Laboratory: 217-545-2214 Research Focus: Molecular Pharmacology Willing to serve as an MPEE mentor? Yes Linda Toth, DVM, Ph.D. Office Location: 801 North Rutledge, Room 1029, Springfield Laboratory Location: 801 North Rutledge, Room 1026, Springfield Phone Office: 217-545-3053 Research Focus: Sleep, Genetics, Neural-Immune Interactions Willing to serve as an MPEE mentor? Yes
Amy Arai, Ph.D. Office Location: 801 North Rutledge, Room 3321, Springfield Laboratory Location: 801 North Rutledge, Room 3275, Springfield Phone Office: 217-545-0228 Laboratory: 217-545-2204 Research Focus: Neuropharmacology Willing to serve as an MPEE mentor? Yes
Don Caspary, Ph.D. Office Location: 801 North Rutledge, Room 3265, Springfield Laboratory Location: 801 North Rutledge, Room 3234, Springfield Phone Office: 217-545-2195 Laboratory: 217-545-2203 Research Focus: Aging in Sensory Systems Willing to serve as an MPEE mentor? Yes
George Dunaway, Ph.D. Office Location: 801 North Rutledge, Room 3329, Springfield Laboratory Location: 801 North Rutledge, Room 3379, Springfield Phone Office: 217-545-2182 Laboratory: 217-545-2218 Research Focus: Role of Cell Division and Cell Death in Development and Loss of Hearing Willing to serve as an MPEE mentor? Yes
Carl Faingold, Ph.D. Office Location: 801 North Rutledge, Room 3289, Springfield Laboratory Location: 801 North Rutledge, Room 3246, Springfield Phone Office: 217-545-2185 Laboratory: 217-545-2206 Research Focus: Investigating Drug Actions on the Brain cfaingold@siumed.edu
Research Area: Epilepsy Summary: This research activity involves the study of how drugs act on the brain to depress or excite the nervous system, involved in epilepsy. Drugs are injected systemically or focally within the brain and neuronal firing and behavior changes are examined. The student will be involved in observation and analysis of the resulting data and analysis of brain slices for locations using histology.
Experience Needed: Previous histological experience would be helpful. Number of Students: 2 Willing to serve as an MPEE mentor? Yes
Tony Lee, Ph.D. Office Location: 801 North Rutledge, Room 3317, Springfield Laboratory Location: 801 North Rutledge, Room 3219 and 3346, Springfield Phone Office: 217-545-2197 Laboratory: 217-545-2215 Research Focus: Septic Shock, Cerebral Blood Vessel Pharmacology Willing to serve as an MPEE mentor? Yes
Dean K. Naritoku, M.D. Office Location: Memorial Medical Center, C402, Springfield Laboratory Location: 801 North Rutledge, Room 3247, Springfield Phone Office: 217-545-5175 Laboratory: 217-545-5818 Research Focus: Clinical Drug Trials; Epilepsy Laboratory-Neuropharmacology; Mechanisms of Anticonvulsants Willing to serve as an MPEE mentor? Yes
Louis Premkumar, Ph.D. Office Location: 801 North Rutledge, Room 3341, Springfield Laboratory Location: 801 North Rutledge, Springfield Phone Office: 217-545-2179 Research Focus: Ion Channels Involved in Memory Formation and Pain Perception Willing to serve as an MPEE mentor? Yes
Vickram Ramkumar, Ph.D. Office Location: 801 North Rutledge, Room 3337, Springfield Laboratory Location: 801 North Rutledge, Room 3338, Springfield Phone Office: 217-545-2171 Laboratory: 217-545-2214 Research Focus: Molecular Pharmacology Willing to serve as an MPEE mentor? Yes
Linda Toth, DVM, Ph.D. Office Location: 801 North Rutledge, Room 1029, Springfield Laboratory Location: 801 North Rutledge, Room 1026, Springfield Phone Office: 217-545-3053 Research Focus: Sleep, Genetics, Neural-Immune Interactions Willing to serve as an MPEE mentor? Yes
Lydia Arbogast, Ph.D. Office Location: Life Science III, Room 2077, Carbondale Laboratory Location: Life Science II, Room 2015 and 2025, Carbondale Phone Office: 618-453-1856 Laboratory: 618-453-8443 Research Focus: Reproductive Neuroendocrinology, Prolactin, Hypothalamic Neurons larbogast@siumed.edu Research Area: Neuroendocrinology Summary: The primary focus of research in Dr. Arbogast's laboratory is understanding how hypothalamic neurons, particularly the tuberoinfundibular dopaminergic neurons, regulate prolactin release from the anterior pituitary. A variety of techniques ranging from whole animal to molecular are used to evaluate how female reproductive hormones alter cellular and molecular processes in the dopaminergic neurons. Experience Needed: Strong background in neuroscience and reproductive physiology. Some laboratory experience preferred. Number of Students: 1 Willing to serve as an MPEE mentor? Yes Brent Bany, Ph.D. Office Location: 2085 Life Science III, Carbondale Laboratory Location: 2007 Life Science III, Carbondale Phone Office: 618-453-1596 Laboratory: 618-453-1506 Research Focus: Uterine Gene Function During Embryo Implantation and Placentation bbany@siumed.edu Research Area: Molecular and cellular uterine biology Summary: The laboratory studies gene function in the endometrium during embryo implantation and placentation using mouse genetic models. Experience Needed: Preferred: Previous experience in a molecular biology and familiarity with instruments used in molecular biology; coursework or other academic background in regulation of gene transcription Required: A dedicated desire to work at the lab bench, learn molecular biology techniques and contribute to group research efforts. Number of Students: 1 Willing to serve as an MPEE mentor? Yes Andrzej Bartke, Ph.D. Office Location: 801 N. Rutledge, Springfield, IL Phone Office: 217-545-7962 Research Focus: Reproductive Endocrinology; Aging; Growth Hormone; Prolactin abartke@siumed.edu Research Area 1: Genetic control of aging; involvement of growth hormone (GH) signaling Summary: The student will have an opportunity to work with mutant, knock-out and transgenic mice in which aging is delayed or accelerated. We are examining the relationship of aging and longevity to GH and body size using animals with GH deficiency, GH resistance, or GH over expression. Our focus is on identifying mechanisms responsible for the effects of GH signaling on longevity. Research Area 2: Effects of growth hormone (GH) and prolactin (PRL) on reproductive function Summary: The student will use animals with GH and PRL deficiency, GH resistance or GH over expression to elucidate the effects of these hormones on puberty, and on female and male reproductive functions. We are particularly interested in the effects of GH and PRL on the release of hypothalamic and pituitary hormones that control reproduction and in the role of growth factors and leptin in mediating these effects. Experience Needed: Any laboratory experience would be helpful but none is essential for participation in the research lab. Number of Students: 2 Willing to serve as an MPEE mentor? Yes Ronald Browning, Ph.D. Office Location: LS III 2076, Carbondale Phone Office: 618-453-7164 rbrowning@siumed.edu Research Area 1: Neuropharmacology of seizures Research Area 2: Neuroanatomical and neurochemical substrates of tonic and clonic convulsions in genetically epilepsy-prone rats Experience Needed: Chemistry Number of Students: 1 Willing to serve as an MPEE mentor? Yes Varadaraj Chandrashekar, Ph.D. Office Location: LS II 250A Phone Office: 618-453-1562 vchandrashekar@siumed.edu Research Area: The role of growth hormone in neuroendocrine and gonadal function in transgenic mice expressing the human growth hormone-releasing hormone gene and in growth hormone receptor gene disrupted mice Summary: It is documented that growth hormone (GH) plays a major role in growth and development. However, the influence of GH in neuroendocrine and reproductive function is poorly understood. It has been shown that GH treatment to oligospermic men improved the effects of gonadotropins in induction of sperm production. It is also known that the sexual maturation is delayed in men with Laron syndrome. This clinical feature is associated with mutated GH receptors and resistance to GH action. Furthermore, administration of GH to hypophysectomized rats increases the LH receptor content of the testis. It has also been demonstrated that a lack of GH secretion results in a delay in testicular growth and differentiation of germinal cells. These studies suggest that GH may play a role in male reproduction. Furthermore, it is not clear whether GH exerts its effects via alterations in the neuroendocrine system that controls gonadal function. Therefore, we are evaluating the neuroendocrine and gonadal functions in transgenic mice expressing the human growth hormone releasing-hormone (hGHRH) gene and in GH receptor gene knock out (GHR-KO) mice. Transgenic mice with the hGHRH gene produce excess GH and insulin-like growth factor-I (IGF-I) and GHR-KO mice do not secrete IGF-I. These mice represent mouse models for "Acromegaly" and "Laron Syndrome" respectively. Therefore, these animals are ideal experimental models to assess the role of GH/IGF-I in neuroendocrine and gonadal functions. In our laboratory, students will be trained to design and execute experiments related to the evaluation of hypothalamic, pituitary, and gonadal functions. Experience Needed: No experience necessary. Number of Students: 1 Willing to serve as an MPEE mentor? Yes Michael Collard, Ph.D. Office Location: LS III 2081, Carbondale Phone Office: 618-453-8430 mcollard@siumed.edu Research Area: Techniques in molecular biology Summary: Current projects in the lab address the molecular biology of cancer and/or gene regulation in testicular germ cells. The student will learn one or more of the following techniques and will possibly contribute data to ongoing research projects: DNA sequencing Plasmid DNA preparation Subcloning of DNA fragments Southern Blotting Northern Blotting Western Blotting Polymerase Chain Reaction Tissue Culture Recombinant Protein production Transient gene expression in mammalian cells cDNA or genomic library screening Confocal fluorescent microscopy Experience Needed: Preferred: Previous experience in a molecular biology lab, familiarity with instruments such as centrifuges and pipetman; experience with DNA or protein isolation and gel electrophoresis, and coursework or other academic background in regulation of gene transcription, the molecular basis of cancer, or male reproduction Required: A strong and dedicated desire to work at the lab bench, learn molecular biology techniques and contribute to group research efforts. Number of Students: Preferably 1 - Possibly 2 Willing to serve as an MPEE mentor? Yes Jodi Huggenvik, Ph.D. Office Location: Life Science III, Room 2053, Carbondale Laboratory Location: Life Science III , Room 2053, Carbondale Phone Office: 618-453-1525 Laboratory: 618-453-8211 Research Focus: Transcription Regulation, Cancer, Tumor Suppressor jhuggenvik@siumed.edu Research Area: Techniques in molecular biology Summary: Our laboratory's focus is the characterization of a mammalian transcription factor that also has properties of a tumor suppressor. The students would learn basic techniques in molecular and cell biology, which may include: Expression vector construction Plasmid DNA purification Restriction enzyme digests DNA sequencing Polymerase chain reaction genotyping tissue culture transcription assays cell proliferation assays Number of Students: 1-2 Willing to serve as an MPEE mentor? Yes Laura Murphy, Ph.D. Office Location: Life Science III, Room 2064, Carbondale Laboratory Location: Life Science III, Room 2033 and 2037, Carbondale Phone Office: 618-453-8212 Laboratory: 618-453-8218 Research Focus: Marijuana and Neuroendocrine Function, Ginseng Effects on Human Cancer Cell Proliferation lmurphy@siumed.edu Research Area 1: Effects of American ginseng on human breast and prostate cancer cell proliferation in culture and in nude mice Research Area 2: Effects of marijuana on the female rat neuroendocrine stress axis Number of Students: 1 Willing to serve as an MPEE mentor? Yes Richard Steger, Ph.D. Office Location: Life Science III, Room 1078, Carbondale Laboratory Location: Life Science III, Room 1021, Carbondale Phone Office: 618-453-1574 Laboratory: 618-453-7162 Research Focus: Neuroendocrinology, Endocrinology Willing to serve as an MPEE mentor? Yes
Lydia Arbogast, Ph.D. Office Location: Life Science III, Room 2077, Carbondale Laboratory Location: Life Science II, Room 2015 and 2025, Carbondale Phone Office: 618-453-1856 Laboratory: 618-453-8443 Research Focus: Reproductive Neuroendocrinology, Prolactin, Hypothalamic Neurons larbogast@siumed.edu
Research Area: Neuroendocrinology Summary: The primary focus of research in Dr. Arbogast's laboratory is understanding how hypothalamic neurons, particularly the tuberoinfundibular dopaminergic neurons, regulate prolactin release from the anterior pituitary. A variety of techniques ranging from whole animal to molecular are used to evaluate how female reproductive hormones alter cellular and molecular processes in the dopaminergic neurons. Experience Needed: Strong background in neuroscience and reproductive physiology. Some laboratory experience preferred. Number of Students: 1 Willing to serve as an MPEE mentor? Yes
Brent Bany, Ph.D. Office Location: 2085 Life Science III, Carbondale Laboratory Location: 2007 Life Science III, Carbondale Phone Office: 618-453-1596 Laboratory: 618-453-1506 Research Focus: Uterine Gene Function During Embryo Implantation and Placentation bbany@siumed.edu
Research Area: Molecular and cellular uterine biology Summary: The laboratory studies gene function in the endometrium during embryo implantation and placentation using mouse genetic models.
Experience Needed: Preferred: Previous experience in a molecular biology and familiarity with instruments used in molecular biology; coursework or other academic background in regulation of gene transcription Required: A dedicated desire to work at the lab bench, learn molecular biology techniques and contribute to group research efforts. Number of Students: 1 Willing to serve as an MPEE mentor? Yes
Andrzej Bartke, Ph.D. Office Location: 801 N. Rutledge, Springfield, IL Phone Office: 217-545-7962 Research Focus: Reproductive Endocrinology; Aging; Growth Hormone; Prolactin abartke@siumed.edu
Research Area 1: Genetic control of aging; involvement of growth hormone (GH) signaling Summary: The student will have an opportunity to work with mutant, knock-out and transgenic mice in which aging is delayed or accelerated. We are examining the relationship of aging and longevity to GH and body size using animals with GH deficiency, GH resistance, or GH over expression. Our focus is on identifying mechanisms responsible for the effects of GH signaling on longevity.
Research Area 2: Effects of growth hormone (GH) and prolactin (PRL) on reproductive function Summary: The student will use animals with GH and PRL deficiency, GH resistance or GH over expression to elucidate the effects of these hormones on puberty, and on female and male reproductive functions. We are particularly interested in the effects of GH and PRL on the release of hypothalamic and pituitary hormones that control reproduction and in the role of growth factors and leptin in mediating these effects. Experience Needed: Any laboratory experience would be helpful but none is essential for participation in the research lab. Number of Students: 2 Willing to serve as an MPEE mentor? Yes
Ronald Browning, Ph.D. Office Location: LS III 2076, Carbondale Phone Office: 618-453-7164 rbrowning@siumed.edu
Research Area 1: Neuropharmacology of seizures Research Area 2: Neuroanatomical and neurochemical substrates of tonic and clonic convulsions in genetically epilepsy-prone rats Experience Needed: Chemistry Number of Students: 1 Willing to serve as an MPEE mentor? Yes
Varadaraj Chandrashekar, Ph.D. Office Location: LS II 250A Phone Office: 618-453-1562 vchandrashekar@siumed.edu
Research Area: The role of growth hormone in neuroendocrine and gonadal function in transgenic mice expressing the human growth hormone-releasing hormone gene and in growth hormone receptor gene disrupted mice Summary: It is documented that growth hormone (GH) plays a major role in growth and development. However, the influence of GH in neuroendocrine and reproductive function is poorly understood. It has been shown that GH treatment to oligospermic men improved the effects of gonadotropins in induction of sperm production. It is also known that the sexual maturation is delayed in men with Laron syndrome. This clinical feature is associated with mutated GH receptors and resistance to GH action. Furthermore, administration of GH to hypophysectomized rats increases the LH receptor content of the testis. It has also been demonstrated that a lack of GH secretion results in a delay in testicular growth and differentiation of germinal cells. These studies suggest that GH may play a role in male reproduction. Furthermore, it is not clear whether GH exerts its effects via alterations in the neuroendocrine system that controls gonadal function. Therefore, we are evaluating the neuroendocrine and gonadal functions in transgenic mice expressing the human growth hormone releasing-hormone (hGHRH) gene and in GH receptor gene knock out (GHR-KO) mice. Transgenic mice with the hGHRH gene produce excess GH and insulin-like growth factor-I (IGF-I) and GHR-KO mice do not secrete IGF-I. These mice represent mouse models for "Acromegaly" and "Laron Syndrome" respectively. Therefore, these animals are ideal experimental models to assess the role of GH/IGF-I in neuroendocrine and gonadal functions. In our laboratory, students will be trained to design and execute experiments related to the evaluation of hypothalamic, pituitary, and gonadal functions. Experience Needed: No experience necessary. Number of Students: 1 Willing to serve as an MPEE mentor? Yes
Michael Collard, Ph.D. Office Location: LS III 2081, Carbondale Phone Office: 618-453-8430 mcollard@siumed.edu
Research Area: Techniques in molecular biology Summary: Current projects in the lab address the molecular biology of cancer and/or gene regulation in testicular germ cells. The student will learn one or more of the following techniques and will possibly contribute data to ongoing research projects:
Experience Needed: Preferred: Previous experience in a molecular biology lab, familiarity with instruments such as centrifuges and pipetman; experience with DNA or protein isolation and gel electrophoresis, and coursework or other academic background in regulation of gene transcription, the molecular basis of cancer, or male reproduction Required: A strong and dedicated desire to work at the lab bench, learn molecular biology techniques and contribute to group research efforts. Number of Students: Preferably 1 - Possibly 2 Willing to serve as an MPEE mentor? Yes
Jodi Huggenvik, Ph.D. Office Location: Life Science III, Room 2053, Carbondale Laboratory Location: Life Science III , Room 2053, Carbondale Phone Office: 618-453-1525 Laboratory: 618-453-8211 Research Focus: Transcription Regulation, Cancer, Tumor Suppressor jhuggenvik@siumed.edu
Research Area: Techniques in molecular biology Summary: Our laboratory's focus is the characterization of a mammalian transcription factor that also has properties of a tumor suppressor. The students would learn basic techniques in molecular and cell biology, which may include:
Number of Students: 1-2 Willing to serve as an MPEE mentor? Yes
Laura Murphy, Ph.D. Office Location: Life Science III, Room 2064, Carbondale Laboratory Location: Life Science III, Room 2033 and 2037, Carbondale Phone Office: 618-453-8212 Laboratory: 618-453-8218 Research Focus: Marijuana and Neuroendocrine Function, Ginseng Effects on Human Cancer Cell Proliferation lmurphy@siumed.edu
Research Area 1: Effects of American ginseng on human breast and prostate cancer cell proliferation in culture and in nude mice
Research Area 2: Effects of marijuana on the female rat neuroendocrine stress axis Number of Students: 1 Willing to serve as an MPEE mentor? Yes
Richard Steger, Ph.D. Office Location: Life Science III, Room 1078, Carbondale Laboratory Location: Life Science III, Room 1021, Carbondale Phone Office: 618-453-1574 Laboratory: 618-453-7162 Research Focus: Neuroendocrinology, Endocrinology Willing to serve as an MPEE mentor? Yes
Glen P. Aylward, Ph.D. Office Location: St. John's Pavilion, 1025 S. 7th, Springfield Phone Office: 217-545-2618 Research Focus: Developmental Assessment; High Risk Infants, Attention and Learning Disorders Willing to serve as an MPEE mentor? Yes Kathy Bottum, M.D., Ph.D. Office Location: Memorial Medical Center, Room 492A, Springfield Laboratory Location: 801 North Rutledge, Room 3354, Springfield Phone Office: 217-545-4234 Laboratory: 217-545-6556 Research Focus: Mechanisms of Protection from Excitotoxicity in Suprachiasmatic Nucleus Neurons kbottum@siumed.edu Research Area: Neuroscience Summary: Molecular biology techniques will be used in cell culture to explore important genes and proteins involved in providing protection from excitotoxicity in neurons. Experience Needed: No experience required. Number of Students: 2 Willing to serve as an MPEE mentor? Yes Larry Hughes, Ph.D. Office Location: 751 North Rutledge, Room 3107, Springfield Laboratory Location: 751 North Rutledge, Room 3106, Springfield 801 North Rutledge, Room 1330, Springfield Phone Office: 217-545-7186 Laboratory: 217-545-7186 Research Focus: Aging, Neurodegenerative Diseases, Psychophysics and Statistics Willing to serve as an MPEE mentor? Yes Cynthia S. Mester, Ph.D., L.C.P.C. Office Location: 751 North Rutledge, Room 3715, Springfield Phone Office: 217-545-3935 Research Focus: Medical Education, Developmental Disabilities, Mental Illness Willing to serve as an MPEE mentor? Yes
Cynthia S. Mester, Ph.D., L.C.P.C. Office Location: 751 North Rutledge, Room 3715, Springfield Phone Office: 217-545-3935 Research Focus: Medical Education, Developmental Disabilities, Mental Illness Willing to serve as an MPEE mentor? Yes
Jerry A. Colliver, Ph.D. Office Location: 801 North Rutledge, Room 3045, Springfield Phone Office: 217-545-4418 Research Focus: Statistics, Research Design, and Measurement Issues Related to Substantive Issues Willing to serve as an MPEE mentor? Yes Steve Verhulst, Ph.D. and Tracey Smith, A.P.R.N., B.C., M.S. Office Location: 913 N. Rutledge, Rm 2105, Springfield Laboratory Location: N/A Phone Office: 217-545-4978 Research Focus: Public and Population Health and Prevention sverhulst@siumed.edu and tsmith@siumed.edu Research Area: Public health Summary: Medical students have different options in which to receive experience. We work with many local health departments and opportunities to be involved in activities at those sites are available. Other projects may be developed in accordance with the student’s interest and talents. Experience Needed: None. Number of Students: 1-5 Willing to serve as an MPEE mentor? Yes
Jerry A. Colliver, Ph.D. Office Location: 801 North Rutledge, Room 3045, Springfield Phone Office: 217-545-4418 Research Focus: Statistics, Research Design, and Measurement Issues Related to Substantive Issues Willing to serve as an MPEE mentor? Yes
Steve Verhulst, Ph.D. and Tracey Smith, A.P.R.N., B.C., M.S. Office Location: 913 N. Rutledge, Rm 2105, Springfield Laboratory Location: N/A Phone Office: 217-545-4978 Research Focus: Public and Population Health and Prevention sverhulst@siumed.edu and tsmith@siumed.edu
Research Area: Public health Summary: Medical students have different options in which to receive experience. We work with many local health departments and opportunities to be involved in activities at those sites are available. Other projects may be developed in accordance with the student’s interest and talents.
Experience Needed: None. Number of Students: 1-5 Willing to serve as an MPEE mentor? Yes
D. Gordon Allan, M.D. Office Location: Memorial Medical Center, D311, Springfield Phone Office: 217-545-8865 Laboratory: 217-545-4968 Research Focus: Adult Orthopaedics Evaluation of Total Hip and Knee Protheses Willing to serve as an MPEE mentor? Yes Carol A. Bauer, M.D. Office Location: St. John's Pavilion 5, 1025 S. 7th Street, Springfield Laboratory Location: 801 N. Rutledge, Room 3205, Springfield Phone Office: 217-545-4777 Laboratory: 217-545-6583 Research Focus: Tinnitus Willing to serve as an MPEE mentor? Yes Theresa M. Boley, R.N., M.S.N., F.N.P.-C.S. Office Location: Memorial Medical Center, D314, Springfield Laboratory Location: 801 N. Rutledge, Laboratory Animal Facility Phone Office: 217-545-5000 Laboratory: 217-545-2211 Research Focus: Clinical: Emphysema, Coronary Artery Disease, Lung Cancer, Esophageal Surgery Laboratory: Minimally Invasive Heart Surgery Willing to serve as an MPEE mentor? Yes Kathleen C. M. Campbell, Ph.D. Office Location: St. John's Pavilion, 5B-507, Springfield Laboratory Location: 801 North Rutledge, Room 3209, Springfield Phone Office: 217-545-4419 Laboratory: 217-545-6774 Research Focus: Ototoxicity and Noise-Induced Hearing Loss. Mechanisms and Development of Otoprotective Agents kcampbell@siumed.edu Research Area: Ototoxicity Summary: In our lab we are investigating the mechanisms of aminoglycoside-induced, cisplatin-induced and noise-induced hearing loss. We are also developing otoprotective agents that can be administered before, during or after ototoxic drugs or noise exposure to prevent permanent hearing loss. We are currently working towards clinical trials. Experience Needed: We work with students from a variety of backgrounds and teach accordingly. Number of Students: 10 Willing to serve as an MPEE mentor? Yes Jose Espinosa, M.D. Office Location: Memorial Medical Center, D405, Springfield Laboratory Location: 911 North Rutledge, Lower Level, Springfield Phone Office: 217-545-8879 Laboratory: 217-545-0254 Research Focus: Epilepsy; Brain Trauma Willing to serve as an MPEE mentor? Yes Stephen Hazelrigg, M.D. Office Location: 800 North Rutledge, Room D314, Springfield Phone Office: 217-545-8875 Research Focus: Clinical: Cardiothoracic Surgery Laboratory: Myocardial Preservation, Minimally Invasive Heart Surgery, Cardiomyopathy Willing to serve as an MPEE mentor? Yes Robert Helfert, Ph.D. Office Location: 801 North Rutledge, Room 4313, Springfield Laboratory Location: 801 North Rutledge, Room 4309, Springfield Phone Office: 217-545-0860 Laboratory: 217-545-3341 Research Focus: Alterations in Synaptic Integrity During Aging Willing to serve as an MPEE mentor? Yes Larry Hughes, Ph.D. Office Location: 751 North Rutledge, Room 3107, Springfield Laboratory Location: 751 North Rutledge, Room 3106, Springfield 801 North Rutledge, Room 1330, Springfield Phone Office: 217-545-7186 Laboratory: 217-545-7186 Research Focus: Aging, Neurodegenerative Diseases, Psychophysics and Statistics Willing to serve as an MPEE mentor? Yes Osaretin Idusuyi, M.D. Office Location: Memorial Medical Center, 701 N. 1st, Room D305, Springfield Laboratory Location: 911 N. Rutledge, Room 301 Phone Office: 217-545-8879 Laboratory: 217-545-4991 (temporary) Research Focus: General Orthopedics, Foot and Ankle, Diabetes Willing to serve as an MPEE mentor? Yes Maria Lebiedowska, M.D. Office Location: 751 North Rutledge, Lower Level 0328, Springfield Laboratory Location: 751 North Rutledge, Lower Level 0328, Springfield Phone Office: 217-545-6556 Laboratory: 217-545-6556 Research Focus: Biomechanics of Human Gait; Quantitative Evaluation of Spasticity Willing to serve as an MPEE mentor? Yes Robert B. McLafferty, M.D. Office Location: Memorial Medical Center, Room D346, 800 N. Rutledge, Springfield Phone Office: 217-545-8444 Research Focus: Peripheral Arterial & Venous Disease, Carotid & Aneurysm Disease Willing to serve as an MPEE mentor? Yes Stephen Milner, M.D. Office Location: 3rd Floor, Baylis, Springfield Laboratory Location: 801 N. Rutledge, Springfield Phone Office: 217-545-6314 Research Focus: Burns and Wound Healing Willing to serve as an MPEE mentor? Yes Michael Neumeister, M.D. Office Location: 747 North Rutledge, 3rd Floor, Springfield Laboratory Location: 801 N. Rutledge, Springfield Phone Office: 217-545-7018 Laboratory: 217-545-3862 Research Focus: Tissue Perfusion, Tissue Engineering Burns Willing to serve as an MPEE mentor? Yes Timothy O'Connor, M.D. Office Location: 800 N. Rutledge, Room D327, Springfield Phone Office: 217-545-8874 Research Focus: Organ Transplant Inspection, Immunosuppressive Properties of Soy Isoflavores Willing to serve as an MPEE mentor? Yes Elizabeth Peralta, M.D. Office Location: 800/D327, Springfield Laboratory Location: 801 Rutledge, Room 4353, Springfield Phone Office: 217-545-7230 Laboratory: 217-545-5860 Research Focus: Breast Cancer, Angiogenesis Willing to serve as an MPEE mentor? Yes Leonard P. Rybak, MD, Ph.D. Office Location: Baylis Building, Room 373, Springfield Laboratory Location: 801 N. Rutledge, Room 4345, Springfield Phone Office: 217-545-2598 Laboratory: 217-545-0955 Research Focus: Mechanisms of Cochlear Injury from Cisplatin and Noise and Methods for Prevention lrybak@siumed.edu Research Area: Ototoxicity Summary: Medical students will receive training in techniques to study auditory function in experimental animals and methods for drug application. Experience Needed: Computer experience would be helpful, but not required. Number of Students: 1 Willing to serve as an MPEE mentor? Yes Andy Wilber, Ph.D. Laboratory Location: 911 N. Rutledge, Room 1329, Springfield Phone Laboratory: 217-545-8098 (Fax: 217-545-6823) Research Focus: Cancer of the Prostate, Kidney, and Bladder awilber@siumed.edu Research Area: Cancer biology Summary: Medical students will receive training in molecular biology and cell biology in an effort to better understand the cause and treatment of urologic cancers. Experience Needed: Basic knowledge of molecular biology and cell culture techniques would be helpful, but is not mandatory. Number of Students: 1 Willing to serve as an MPEE mentor? Yes Bradon Wilhelmi, M.D. Office Location: 747 N. Rutledge, 3rd Floor, Springfield Laboratory Location: 801 N. Rutledge, Springfield Phone Office: 217-545-7018 Research Focus: Anatomy, Wound Healing, Skin Flap Physiology Willing to serve as an MPEE mentor? Yes
D. Gordon Allan, M.D. Office Location: Memorial Medical Center, D311, Springfield Phone Office: 217-545-8865 Laboratory: 217-545-4968 Research Focus: Adult Orthopaedics Evaluation of Total Hip and Knee Protheses Willing to serve as an MPEE mentor? Yes
Carol A. Bauer, M.D. Office Location: St. John's Pavilion 5, 1025 S. 7th Street, Springfield Laboratory Location: 801 N. Rutledge, Room 3205, Springfield Phone Office: 217-545-4777 Laboratory: 217-545-6583 Research Focus: Tinnitus Willing to serve as an MPEE mentor? Yes
Theresa M. Boley, R.N., M.S.N., F.N.P.-C.S. Office Location: Memorial Medical Center, D314, Springfield Laboratory Location: 801 N. Rutledge, Laboratory Animal Facility Phone Office: 217-545-5000 Laboratory: 217-545-2211 Research Focus: Clinical: Emphysema, Coronary Artery Disease, Lung Cancer, Esophageal Surgery Laboratory: Minimally Invasive Heart Surgery Willing to serve as an MPEE mentor? Yes
Kathleen C. M. Campbell, Ph.D. Office Location: St. John's Pavilion, 5B-507, Springfield Laboratory Location: 801 North Rutledge, Room 3209, Springfield Phone Office: 217-545-4419 Laboratory: 217-545-6774 Research Focus: Ototoxicity and Noise-Induced Hearing Loss. Mechanisms and Development of Otoprotective Agents kcampbell@siumed.edu
Research Area: Ototoxicity Summary: In our lab we are investigating the mechanisms of aminoglycoside-induced, cisplatin-induced and noise-induced hearing loss. We are also developing otoprotective agents that can be administered before, during or after ototoxic drugs or noise exposure to prevent permanent hearing loss. We are currently working towards clinical trials.
Experience Needed: We work with students from a variety of backgrounds and teach accordingly. Number of Students: 10 Willing to serve as an MPEE mentor? Yes
Jose Espinosa, M.D. Office Location: Memorial Medical Center, D405, Springfield Laboratory Location: 911 North Rutledge, Lower Level, Springfield Phone Office: 217-545-8879 Laboratory: 217-545-0254 Research Focus: Epilepsy; Brain Trauma Willing to serve as an MPEE mentor? Yes
Stephen Hazelrigg, M.D. Office Location: 800 North Rutledge, Room D314, Springfield Phone Office: 217-545-8875 Research Focus: Clinical: Cardiothoracic Surgery Laboratory: Myocardial Preservation, Minimally Invasive Heart Surgery, Cardiomyopathy Willing to serve as an MPEE mentor? Yes
Robert Helfert, Ph.D. Office Location: 801 North Rutledge, Room 4313, Springfield Laboratory Location: 801 North Rutledge, Room 4309, Springfield Phone Office: 217-545-0860 Laboratory: 217-545-3341 Research Focus: Alterations in Synaptic Integrity During Aging Willing to serve as an MPEE mentor? Yes
Osaretin Idusuyi, M.D. Office Location: Memorial Medical Center, 701 N. 1st, Room D305, Springfield Laboratory Location: 911 N. Rutledge, Room 301 Phone Office: 217-545-8879 Laboratory: 217-545-4991 (temporary) Research Focus: General Orthopedics, Foot and Ankle, Diabetes Willing to serve as an MPEE mentor? Yes
Maria Lebiedowska, M.D. Office Location: 751 North Rutledge, Lower Level 0328, Springfield Laboratory Location: 751 North Rutledge, Lower Level 0328, Springfield Phone Office: 217-545-6556 Laboratory: 217-545-6556 Research Focus: Biomechanics of Human Gait; Quantitative Evaluation of Spasticity Willing to serve as an MPEE mentor? Yes
Robert B. McLafferty, M.D. Office Location: Memorial Medical Center, Room D346, 800 N. Rutledge, Springfield Phone Office: 217-545-8444 Research Focus: Peripheral Arterial & Venous Disease, Carotid & Aneurysm Disease Willing to serve as an MPEE mentor? Yes
Stephen Milner, M.D. Office Location: 3rd Floor, Baylis, Springfield Laboratory Location: 801 N. Rutledge, Springfield Phone Office: 217-545-6314 Research Focus: Burns and Wound Healing Willing to serve as an MPEE mentor? Yes
Michael Neumeister, M.D. Office Location: 747 North Rutledge, 3rd Floor, Springfield Laboratory Location: 801 N. Rutledge, Springfield Phone Office: 217-545-7018 Laboratory: 217-545-3862 Research Focus: Tissue Perfusion, Tissue Engineering Burns Willing to serve as an MPEE mentor? Yes
Timothy O'Connor, M.D. Office Location: 800 N. Rutledge, Room D327, Springfield Phone Office: 217-545-8874 Research Focus: Organ Transplant Inspection, Immunosuppressive Properties of Soy Isoflavores Willing to serve as an MPEE mentor? Yes
Elizabeth Peralta, M.D. Office Location: 800/D327, Springfield Laboratory Location: 801 Rutledge, Room 4353, Springfield Phone Office: 217-545-7230 Laboratory: 217-545-5860 Research Focus: Breast Cancer, Angiogenesis Willing to serve as an MPEE mentor? Yes
Leonard P. Rybak, MD, Ph.D. Office Location: Baylis Building, Room 373, Springfield Laboratory Location: 801 N. Rutledge, Room 4345, Springfield Phone Office: 217-545-2598 Laboratory: 217-545-0955 Research Focus: Mechanisms of Cochlear Injury from Cisplatin and Noise and Methods for Prevention lrybak@siumed.edu
Research Area: Ototoxicity Summary: Medical students will receive training in techniques to study auditory function in experimental animals and methods for drug application.
Experience Needed: Computer experience would be helpful, but not required. Number of Students: 1 Willing to serve as an MPEE mentor? Yes
Andy Wilber, Ph.D. Laboratory Location: 911 N. Rutledge, Room 1329, Springfield Phone Laboratory: 217-545-8098 (Fax: 217-545-6823) Research Focus: Cancer of the Prostate, Kidney, and Bladder awilber@siumed.edu
Research Area: Cancer biology Summary: Medical students will receive training in molecular biology and cell biology in an effort to better understand the cause and treatment of urologic cancers.
Experience Needed: Basic knowledge of molecular biology and cell culture techniques would be helpful, but is not mandatory. Number of Students: 1 Willing to serve as an MPEE mentor? Yes
Bradon Wilhelmi, M.D. Office Location: 747 N. Rutledge, 3rd Floor, Springfield Laboratory Location: 801 N. Rutledge, Springfield Phone Office: 217-545-7018 Research Focus: Anatomy, Wound Healing, Skin Flap Physiology Willing to serve as an MPEE mentor? Yes