Janak Koirala, MD, MPH, FACP
Division of Infectious Diseases
Associate Professor of Clinical Medicine

Current Laboratory Research Projects:

1. Interferon-gamma to improve macrophage functions against MAC (Mycobacterium avium complex) infection in HIV-infected patients
2. In vitro MAC (Mycobacterium avium complex) antigen assay to screen for MAC infection
3. In vitro antimicrobial susceptibility test for Multidrug Resistant Acinetobacter baumanii

1. HIV/AIDS Education and Prevention in Central Illinois
2. Prevention and Self-Treatment of Diarrhea in International Travelers
3. An International, Multicenter, Prospective Observational Study of the Safety of Maraviroc Used With Optimized Background Therapy in Treatment Experienced HIV-1 Infected Patients (Pfizer Protocol # A4001067)
4. A Phase IV, Multi-center, Cross-Sectional Study to Evaluate the I50L Substitution among Subjects Experiencing Virologic Failure on a HAART regimen containing Atazanavir

Please visit divisional research website for a complete list: http://www.siumed.edu/medicine/infec/research.htm

1. Diagnosis and management of all infectious diseases
2. Travel Medicine and immunization
   

Scientific Journals:

1. Janak Koirala, Nancy Khardori. Infections in Burn Wounds. Infectious Disease Practice for Clinicians. August-September 2007;31:601-605.
2. J. Koirala, S. D. Gandotra, S. Rao, G. Sangwan, A. Mushtaq, T. H. Htwe, A. Adamski,
   D. Blessman and N. M. Khardori. Granulocyte colony-stimulating factor dosing in pegylated interferon alpha-induced neutropenia and its impact on outcome of anti-HCV therapy. Journal of Viral Hepatitis, 2007, 14, 782–787.
3. Bergman SJ, Speil C, Short M, Koirala J. Pharmacokinetic and pharmacodynamic aspects of antibiotic use in high-risk populations. Infect Dis Clin North Am. 2007 Sep;21(3):821-46.
4. Gupta S, Koirala J, Khardori R, Khardori N. Infections in diabetes mellitus and hyperglycemia. Infect Dis Clin North Am. 2007 Sep;21(3):617-38.
5. Strategies for Management of Antiretroviral Therapy (SMART) Study Group (includes J Koirala), Lundgren JD, Babiker A, El-Sadr W, Emery S, Grund B, Neaton JD, Neuhaus J, Phillips AN. Inferior clinical outcome of the CD4+ cell count-guided antiretroviral treatment interruption strategy in the SMART study: role of CD4+ Cell counts and HIV RNA levels during follow-up. J Infect Dis. 2008 Apr 15;197(8):1145-55.
6. Strategies for Management of Antiretroviral Therapy (SMART) Study Group (includes J Koirala), Emery S, Neuhaus JA, Phillips AN, Babiker A, Cohen CJ, Gatell JM, Girard PM, Grund B, Law M, Losso MH, Palfreeman A, Wood R. Major clinical outcomes in antiretroviral therapy (ART)-naive participants and in those not receiving ART at baseline in the SMART study. J Infect Dis. 2008 Apr 15;197(8):1133-44.

Book Chapters:

1. Koirala J. Plague: Endemic, Epidemic and Bioterrorism. In: Khardori N, ed. 1st ed. Bioterrorism Preparedness: A Global Medical, Legal and Public Health Perspective. Weinheim, Germany: Wiley-VCH, 2006; 147-162.
2. Koirala J. Botulism: Toxicology, Clinical Presentations and Management. In: Khardori N, ed. 1st ed. Bioterrorism Preparedness: A Global Medical, Legal and Public Health Perspective. Weinheim, Germany: Wiley-VCH, 2006: 163-180.
3. Koirala J. Tularemia: Natural Disease versus Act of Terrorism. In: Khardori N, ed. 1st ed. Bioterrorism Preparedness: A Global Medical, Legal and Public Health Perspective. Weinheim, Germany: Wiley-VCH, 2006: 181-194.

e-Publications:

1. Koirala J. Mycobacterium kansasii. eMedicine Journal 2001; 2(12). An on-line medical reference; published by Emedicine inc. (Revisions: 4/16/2006)
   Available at: http://www.emedicine.com/med/
2. Koirala J, Harley WB. Mycobacterium avium intracellulare. eMedicine Journal 2006; 2(12). An on-line medical reference; published by eMedicine inc. (Revisions: May 2008)
   Available at: http://www.emedicine.com/med/topic1532.htm
3. Koirala J, Htwe TH, Speil C. Lyme Disease. BMJ Point of Care for PDA; published by: epocrates inc., 2008. Available at: http://bmj-preview.epocrates.com