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Southern Illinois University School of Medicine
SIU Physicians & Surgeons

CLINICAL RESEARCH STUDIES

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Click here to view a list of current research studies

SIU Physicians & Surgeons and the SIU School of Medicine are committed to the advancement of medical knowledge for the benefit of society. As medical research advances, the treatment of many human diseases and conditions also advances.

Clinical research trials are conducted at SIU School of Medicine in order to gain knowledge that may help future patients. This is different from routine health care that is based upon the best known treatment and is provided with the goal of helping an individual patient. The medical school has several committees that review research projects. For example, clinical trials are carefully reviewed for compliance with federal and state regulations by the Springfield Committee for Research Involving Human Subjects. Clinical trials are generally funded by pharmaceutical companies. Other research projects at the medical school are funded by the federal government, including the National Institutes of Health, health associations, private foundations and the State of Illinois. If you decide to take part in any study and are accepted, there may or may not be direct medical benefits to you. Specific details of each clinical trial vary. While there usually is no charge to the participants for tests and medications directly related to studies, there may be added costs to you and/or your insurance company for continuing medical care and/or hospitalization. Results of studies are usually shared with your personal physician. These matters should be discussed with the SIU faculty physician responsible for the study and/or the study coordinator as part of the process of giving informed consent.

Information about various clinical trials is posted by department as it is provided by SIU faculty physicians. Visitors to this website can contact the study coordinator via email or phone regarding possible participation.

Department of Internal Medicine

Department of Neurology

Department of Psychiatry

Department of Surgery


Study information is listed by clinical departments
(Click study title for details)

DEPARTMENT OF INTERNAL MEDICINE RESEARCH

An Exercise Intervention for Breast Cancer Patients (BEAT Cancer Trial)

    Sponsoring Department: Medicine - General Internal Medicine Division
    SIU Faculty Physician: Laura Q. Rogers , M.D.

Cystic Fibrosis Patient Registry

    Sponsoring Department: Medicine - Pulmonary and Critical Care Medicine Division
    SIU Faculty Physician: Lanie E. Eagleton, M.D.

"EXCELS"-Epidemiologic study of Xolair (OMALIZUMAB)

    Sponsoring Department: Medicine - Pulmonary and Critical Care Medicine Division
    SIU Faculty Physician: Joseph Henkle, MD

"PAHQuERI"-Pulmonary Hypertension Quality Enhancement Research Initiative

    Sponsoring Department: Medicine - Pulmonary and Critical Care Medicine Division
    SIU Faculty Physician: Kent Kapitan , MD

The Effect of Weight Loss on Bronchial Hyperreactivity in Obese Asthmatics: a Prospective Cohort Study

    Sponsoring Department: Medicine - Pulmonary and Critical Care Medicine Division
    SIU Faculty Physician: Patricia Hopkins-Price, PhD

Randomized, Double-Blind, Parallel-Group, Multinational Trial of Intravenous Telavancin vs Vancomycin for Treatment of Hospital-Acquired Pneumonia with a Focus on Patients with Infections Due to MRSA

    Sponsoring Department: Medicine - Infectious Diseases Division
    SIU Faculty Physician: Janak Koirala, MD

Brain Derived Neutrotrophic Factor (BDNF) as a Marker for Major Depressive Disorder in Women

Clinical Testing of the Anti-Diabetic Effects of High-Isoflavone Soy Protein

    Sponsoring Department: Internal Medicine
    SIU Faculty Physician: Romesh Khardori, MD and William Banz, PhD

Quality of Life, Physical Functioning and Head and Neck Cancer (LIPHT)

    Sponsoring Department: Medicine - General Internal Medicine Division
    SIU Faculty Physician: Laura Q. Rogers , M.D.

DEPARTMENT OF NEUROLOGY RESEARCH

A Study of an Investigational Drug -- SPM 927 -- for use as additional treatment for individuals with partial seizures

A Study of the Effectiveness and Safety of Talampanel as Additional Treatment in Individuals with Partial Seizures

DEPARTMENT OF PSYCHIATRY RESEARCH

 

DEPARTMENT OF SURGERY RESEARCH

A Study of the Occult Metastases in the Patients Undergoing Surgery for Non-Small Cell Lung Cancer - Ending Date: 2008

A Study of Lymph Node Sampling During Lung Surgery for Non-Small Cell Cancer - Ending Date: 2008

A Study of an Investigational Drug to Treat Coronary Vein Grafts Used in Coronary Artery Bypass Graft Procedure - Ending Date: 2008

A Study of the Efficacy of New TissueLink Bipolar Forceps

A Study of Thoracoscopic Treatment for Diffuse Bullous Emphysema - Ending Date: 2010

US Patient Registry Protocol: ATS Open Pivot® Heart Valve Intra-Operative Assessment (OPIA) Revision B

Comparison of Behavioral Outcomes for Lung Cancer Patients in Educational Versus Working Support Groups

Randomized, Multicenter, Placebo-Controlled Double-Blind, Parallel Group Study of INS50589 Intravenous Infusion in Subjects Undergoing Coronary Artery Bypass Graft Surgery Involving Cardiopulmonary Bypass

Heart Surgery Database

Intraoperative I-125 Brachytherapy Following Sublobar Resection in High Risk Patients with Stage I Non-Small Cell Lung Carcinoma

Lung Surgery Database

The Effect of Sternotomy versus Video-Assisted Thoracic Surgery on Postoperative Pain and Associated Complications of Pulmonary Resection Patients

The Use Of A Supplemental Pleural Drain To Reduce Pleural Effusion After Coronary Artery Bypass Grafting: A Prospective Randomized Study

Use Of Proteomic Analysis Of Serum Samples For Detection of Non-Small Cancer

Randomized Evaluation of a Surgical Treatment for Off-Pump Repair of the Mitral Valve

RTOG 0214: A Phase III Comparison of Prophylactic Cranial Irradiation Versus Observation in Patients with Locally Advanced Non-Small Cell Lung Cancer

RTOG 0229 -- A Phase 11 Trial of Neoadjuvant Therapy with Concurrent Chemotherapy and High Dose Radiotherapy Followed By Surgical Resection and Consolidation Therapy for Locally Advanced Non -- Small Cell Lung Carcinoma

RTOG 0412: Phase III Randomized Trail of Preoperative Chemotherapy Versus Preoperative Concurrent Chemotherapy and Thoracic Radiotherapy Followed by Surgical Resection and Consolidation Chemotherapy in Favorable Prognosis Patients with State IIIA (N2) Non Small Cell Lung Cancer

Surgery Database

SIU-Surgery Subspecialty- Family Practice Telehealth Collaboration

Thoracoscopic Treatment of Diffuse Bullous Emphysema

Protocol for Obtaining Solid Tissues, Fluids, and Information for research for The SIU Tissue Banking Facility

VENT: Endobronchial Valve for Emphysema Palliation Trial

American College of Surgeons Oncology Group Z4032 A Randomized Phase III Study of Sublobar Resection Versus Sublobar Resection Plus Brachytherapy in High Risk Patients With Non-Small Cell Lung Cancer(NSCLC), 3cm or Smaller

Study of AcuMatch M-Series-Exactech Integrated Hip System

A Study of the VerSys Hip System

A Study to Confirm the Safety and Efficacy of PROCRIT Administered Perioperatively

    Sponsoring Department: Surgery/Division of Orthopaedics
    SIU Faculty Physician: Per Freitag, M.D.

A Study of NexGen Complete Knee Solution

A Study of NexGen Complete Knee Solution

A Study of the Cormet 2000 Metal on Metal Resurfacing Hip System