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Thomas J. Brozoski
Division of Otolaryngology, Department of Surgery
801 N. Rutledge St., P.O. Box 19629
Southern Illinois University School of Medicine
Springfield, IL 62794
Email:   tbrozoski@siumed.edu
Tel:  217-545-6583

Employment

1999 - present
Research Professor
Division of Otolaryngology,
Department of Surgery
Southern Illinois University
School of Medicine
1997 - 2002
Adjunct Professor
Psychology Program
University of Illinois at Springfield
1997
Professor of Psychology
Grinnell College
Retired, December, 1997

Research Consultant
Division of Otolaryngology
Department of Surgery
Southern Illinois University
School of Medicine

Visiting Professor
Psychology Program
University of Illinois at Springfield

1992 - 1988
Professor and Chairman
Psychology Department
Grinnell College

1986 – 88
Chairman, Division of Science
Grinnell College

1977 - 1986
Associate Professor of Psychology
Chairman, Psychology Department Grinnell College
1976 - 77
Postdoctoral Fellow
Section on Developmental
Neuropsychology
Laboratory of Neuropsychology
National Institute of Mental Health
Bethesda, Maryland 20205
1975 - 76
N. S. F. Postdoctoral Fellow
Department of Pharmacology
School of Medicine
University of Michigan
Ann Arbor, Michigan 48106
1972 - 75
Assistant Professor
Psychology Department
Grinnell College
1969 - 72
Instructor
Psychology Department
Grinnell College

Education

Degrees

Ph.D., Psychology, University of Virginia, 1971
M.S., Psychology, University of Wisconsin, 1966
B.S., Psychology, University of Wisconsin, 1964

 

Grants and Awards

National Institute on Deafness and Communicative Disorders,Co-investigator, Features of chronic tinnitus in an animal model as indicated by MEMRI and MRS, # DC009669, $1,828,350, 2008 – 2013.

Tinnitus Research Consortium
Co-investigator, The effect of tinnitus retraining therapy on subjective and objective measures of chronic tinnitus. $ 269,315, 2005-2007.

Tinnitus Research Consortium
Co-investigator, Clinical efficacy of gabapentin as a treatment for noise-induced and age-associated tinnitus. $186,000. 2003-2005.

National Institute on Deafness and Communicative Disorders
Co-investigator, Peripheral and central mechanisms of tinnitus generation, # DC04830-01A1,  $1,065,280, 2002 – 2006.

National Institute on Deafness and Communicative Disorders
Co-investigator, A behavioral model of chronic tinnitus, # DC96-003,
1997-1999,  $196,594

American Tinnitus Foundation
Co-investigator, Development of an animal model for tinnitus, 1992,  $6800

Associated Colleges of the MidwestACM Minority Scholar Mentor,1991,  $1500

Pew Charitable Trust,Small Research grant,1990,  $3400

Pew Charitable Trust,Small Research grant,1989,  $2700

Joyce Foundation,Research Mentor grant 1988,  $2700

Pew Charitable Trust Laboratory Equipment, 1987-1988,  $200,000

Sloan Foundation Computer Applications in Psychology,1986,  $20,000

Grinnell College Noyce Faculty Computing Award,1986,  $2500

National Science Foundation Principal Investigator,  CSIP grant, 1986,  $80,000

National Science Foundation Principal Investigator, ISEP grant,
1979,  $27,000

NIMH Postdoctoral Training grant 1976-1977, $13,000 National Science Foundation
Science Faculty Postdoctoral Fellowship,1975-1976, $20,000

NIMH Small Research grant 1970-1971,  $10,000

NDEA Title IV Predoctoral Fellowship 1966-1969, $14,500


Peer-reviewed Publications

 

  1. Bauer, C and Brozoski TJ (2008) Tinnitus retraining therapy: Impact on loudness, annoyance, and habituation to tinnitus. In Evidence-Based Otolaryngology., JJ Shin, CJ Hartnick, GW Randolph, Eds., Springer Science+Business Media, LLC: New York. Pp 360-364.
  2. Brozoski TJ and Bauer CA (2008) Learning about tinnitus from an animal model. Semin Hear. Aug;29(3):242-258.
    Bauer CA, Turner JG, Caspary DM, Myers KS, Brozoski TJ. (2008) Tinnitus and inferior colliculus activity in chinchillas related to three distinct patterns of cochlear trauma. J Neurosci Res. 86, 2564–78.
  3. Bauer C and Brozoski T (2008) Tinnitus: Theories, Mechanisms and Treatments., in Auditory Trauma, Protection, and Treatment., D. Webster, A. Popper, and R. Fay, Eds., Springer-Verlag: New York. Pp 101 – 129.
  4. Bauer CA and Brozoski TJ (2007) Gabapentin, Prog Brain Res. 2007;166:287-301.
  5. Brozoski, T.J., Ciobanu, L., Bauer, C.A. (2007) Central neural activity in rats with tinnitus evaluated with manganese-enhanced magnetic resonance imaging (MEMRI). Hear Res. June;228(1-2):168-179.
  6. Brozoski TJ, Spires, JTJ, Bauer, CA (2007). Vigabatrin, a GABA Transaminase Inhibitor, Reversibly Eliminates Tinnitus in an Animal Model. J Assoc Res Otolaryngol 8, 105-18.
  7. Bauer CA, Brozoski TJ, (2006). Effect of gabapentin on the sensation and impact of tinnitus. Laryngoscope 116:  675-81.
  8. Turner JG, Brozoski TJ, Bauer CA, Parrish JL, Myers K, Hughes LF, Caspary DM, (2006) Gap Detection Deficits in Rats with Tinnitus: A Potential Novel Screening Tool. Beh Neurosci.120: 188-95.
  9. Brozoski TJ, Caspary DM, Bauer CA, (2005) Marking multi-channel silicon-substrate electrode recording sites using radiofrequency lesions. J Neurosci Methods. 150: 185-91.
  10. Bauer CA, Brozoski TJ. (2005). Cochlear structure and function after round window application of ototoxins. Hear Res, 201:121-31
  11. Brozoski TJ, Bauer CA, (2005). The effect of dorsal cochlear nucleus ablation on tinnitus in rats. Hear Res. Aug;206(1-2):227-36.
  12. Brozoski TJ, Bauer CA, Caspary DM (2002). Elevated fusiform cell activity in the dorsal cochlear nucleus of chinchillas with psychophysical evidence of tinnitus. Journal of Neuroscience 22: 2383-2390.
  13. Bauer CA,  Brozoski TJ (2001). Assessing tinnitus and prospective tinnitus therapeutics using a psychophysical animal model. J Assoc Res Otolaryngol. 2, 54-64.
  14. Bauer CA, Brozoski TJ, Holder TM, Caspary DM (2000). Effects of chronic salicylate on GABAergic activity in rat inferior colliculus. Hear Res. 141, 175-182.
  15. Bauer CA, Brozoski TJ, Rojas R, Boley J, Wyder M (1999).  A behavioral model of chronic tinnitus in rats. Otolaryngology – Head and Neck Surgery. 121(4), 457-462.
  16. Seeley RJ,  Brozoski TJ (1989). Measurement and quantification of stereotypy:  An information analysis. Behavior Research Methods, Instruments, and Computers, 21, 271 - 274.
  17. Brozoski TJ,  Altemus KL (1986). Conditionability of caudate dopamine activity in the caudate nucleus of cats demonstrated by in vivo electrochemistry. Brain Res, 364, 275-283.
  18. Brozoski TJ, Brown RM, Goldman PS,  Ptak JE (1979). Cortical catecholamines and cognitive performance in the monkey., in E. Usdin, I.J. Kopin, and J. Barchas, (eds)  Catecholamines:  Basic and Clinical Frontiers, vol. 2, New York: Pergamon Press, 1681-1683.
  19. Brozoski TJ, Brown RM, Rosvold HE,  Goldman PS (1979). Cognitive deficit caused by regional depletion of dopamine in prefrontal cortex of rhesus monkey. Science, 205, 929-932.

Presentations

  • Bauer CA, Ciobanu L, Brozoski TJ. Central neural activity in rats with tinnitus evaluated with MEMRI. International Society for Magnetic Resonance Imaging, Seattle Washington, May 6 2006
  • Bauer CA, Myers KS, Brozoski TJ. Acoustic injury and TRPV1 expression in the cochlear spiral ganglion, Association for Research in Otolaryngology, Baltimore Maryland, February 2006
  • Bauer CA, Brozoski TJ.  The neuropathy of tinnitus: knowledge gained from an animal model.  International Symposium on Pharmacologic Strategies for Prevention and Treatment of Hearing Loss.  Niagra Falls, Ontario. October 2005.
  • Turner JG, Brozoski TJ, Bauer, CA, Parrish JL, Myers K, Hughes LF, Caspary DM (2005). Gap detection deficits and startle habituation changes in rats with psychophysical evidence of tinnitus. Program No. 163.12. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. Online.
  • Wang H, Ling L, Hughes LF, Bauer CA, Brozoski TJ, Caspary DM, (2005). Altered markers of glycinergic function in the DCN of a rat model of tinnitus. Program No. 163.12. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. Online.
  • Turner JG, Brozoski TJ, Bauer CA, Parrish JL, Myers K, Hughes L, Caspary DM. (2005). A Novel Technique for Rapid Tinnitus Screening in Rats. Acoustical Society of North America, Vancouver, BC.
  • Brozoski T, Bauer C, Turner J, Caspary C. (2005). Neural Activity in the Inferior Colliculus, and Psychophysical Evidence of Tinnitus in Chinchillas, Association for Research in Otolaryngology, New Orleans, LA, 2005, 2005. Vol. ARO Abstract 319, Volume 28, 2005.
  • Turner J, Parrish J, Hughes L, Wang H, Brozoski T, Bauer C, Caspary D. (2005). Behavioral Gap Detection Deficits in the Fischer Brown Norway (FBN) Rat Model of Presbycusis, Association for Research in Otolaryngology, New Orleans, LA, 2005, 2005. Vol. ARO Abstract 206, Volume 28, 2005.
  • Brozoski, TJ (2004). From an Animal Model to a Clinical Trial: Translational Research in Tinnitus.  Invited speaker: Iowa Tinnitus Workshop, Department of Otolaryngology, Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA.
  • Brozoski TJ, Bauer CA (2004). The dorsal cochlear nucleus and tinnitus. Invited speaker: Conference on plasticity in the auditory system, Jackson, WY.
  • CA, Johnston CY,  Brozoski TJ (2004). Cochlear structure and function after round window application of ototoxins. Middle and Southern Section of the American Triologic Society, Marco Island, FL.
  • Brozoski TJ, Bauer CA, Campbell M (2003). Is the dorsal cochlear nucleus a central source of trauma-induced tinnitus? Association for Research in Otolaryngology, Daytona Beach, FL.
  • Bauer CA, Heffernan T, Hamilton-Hill G, Brozoski TJ,  Caspary D (2001). Psychophysical evidence of chronic tinnitus in chinchillas after unilateral acoustic trauma. Association for Research in Otolaryngology, St. Petersburg, FL.
  • Brozoski TJ, Bauer CA,  Bergschneider M (2000). GABAergic Modulation of Noise-Induced Tinnitus in Rats. Association for Research in Otolaryngology, St. Petersburg, FL.
  • Bauer CA, McMasters DL, Gaines A, Herr LA,  Brozoski TJ (1999). Behavioral evidence of chronic tinnitus in rats after unilateral noise trauma. Association for Research in Otolaryngology, St. Petersburg, FL.
  • Bauer CA, Herr LA,  Brozoski TJ (1998). Behavioral evidence of chronic tinnitus in rats after unilateral noise trauma. Neuroscience Abstracts, 24, 1634.
  • Bauer CA, Brozoski TJ, Rojas R, Boley J, Wyder M,  Caspary DM (1998). The effects of salicylate on conditioned suppression behavior and receptor pharmacology in the inferior colliculus of the Long-Evans rat.  Association for Research in Otolaryngology, St. Petersburg, FL
  • Bauer CA, Brozoski TJ, Caspary DM, Rojas R, Boley J (1997).  A behavioral model of chronic tinnitus in rats. Annual Meeting of the American Academy of Otolaryngology-Head and Neck Surgery.  Abstract in Otolaryngology - Head and Neck Surgery, 117(2) 88.
  • Brozoski TJ, Wyder M, Bauer CA (1996). An animal model of tinnitus that reflects some of the qualitative features and the persistence of the disorder. Neuroscience Abstracts, 22, 1821.
  • Brozoski TJ, Brozoski DT,  Kim M (1995).  Dynamics of mesolimbic and nigrostriatal dopamine activity, during appetitive Pavlovian conditioning, as determined by in vivo electrochemical detection. Neuroscience Abstracts, 21, 1217.
  • Brozoski DT,  Brozoski TJ (1993). Dopaminergic activity in the nucleus accumbens during reinforcing stimuli. Pew Undergraduate Research Symposium in the Biological Sciences and Psychology, Oct. 11th, Washington University, St. Louis, Mo.
  • Sipes VEW, Brozoski TJ,  Bauer CA (1993). Frequency characteristics of salicylate-induced tinnitus in rats: An animal model for a human auditory disorder. Pew Undergraduate Research Symposium in the Biological Sciences and Psychology, Oct. 11th, Washington University, St. Louis, Mo.
  • Brozoski TJ, Gardner GA,  Cox ME (1993). A comparison of mesolimbic and nigrostriatal dopaminergic activity during food consumption and conditioned appetitive behavior, as determined by in vivo elecytrochemical detection. Presented at the 23rd annual meeting of the Society for Neuroscience.
  • Bauer CA, Brozoski TJ,  McCabe BF (1992). A variation of the conditioned suppression model of salicylate-induced tinnitus in rats.  Annual Meeting of the American Academy of Otolaryngology - Head and Neck Surgery, Washington, D.C., Abstract: Otolaryngology - Head and Neck Surgery, 107, No. 2, 234.
  • Brozoski TJ, Stenvers K, Athorp A, Skeen G, Brozoski EL, Oeth KM,  Green JS (1991). Nigrostriatal dopaminergic activity, as determined by in vivo electrochemical detection, during food consumption and conditioned consummatory behavior.  Neuroscience Abstracts, 17, 327.
  • Seeley RJ,  Brozoski T J (1988). Measurement and quantification of stereotypy in freely behaving subjects: An information Analysis.  Society for Computers in Psychology. November 9.
  • Brozoski TJ (1987a). Introduction to distributed processing and networking: The evolution of microcomputing in the Department of Psychology at Grinnell.  Seminar in Networking.  Computer Services, Grinnell College, March 16.
  • Brozoski TJ (1987b). Interfaces for microcomputer applications in experimental psychology.  Iowa Academy of Science. April 24.
    Brozoski TJ (1984). Dopamine and dopamine metabolite changes during instrumental conditioning:  An in vivo electrochemical analysis. Fourth Annual MIU  Neuroscience Conference. June 25-26.
  • Brozoski TJ, Moon PF, Schaufler KD (1983). Conditioned discrimination learning and striatal dopamine turnover.  Presented at the Fifth International  Catecholamine Symposium, Gothenborg, Sweden.
  • Anson JA, Whiting DM,  Brozoski TJ (1980). Dopamine turnover in discrimination learning in the rat. Presented at the Midwestern Psychological Association, St. Louis.
  • Greenfield M, Anson J, Whiting D,  Brozoski TJ (1979). Dopamine turnover in the caudate nucleus in relation to discrimination learning.  Presented at the Psychology, A Second Century, Conference, Luther College.
  • Brozoski TJ (1978). Prefrontal dopamine and delayed-alternation performance deficits in the monkey.  Presented at the Fourth International Catecholamine Symposium. Pacific Grove, California.


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