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 Michael J. Brenner, M.D..
Facial Plastic Surgeon
Brief Bio
Michael J. Brenner, M.D., Assistant Professor of Surgery, is a fellowship trained facial plastic surgeon. He directs the new Facial Plastic & Reconstructive Surgery Program in the Division of Otolaryngology at SIU School of Medicine. His practice focuses on cosmetic and reconstructive surgery of the face, head and neck.
Dr. Brenner was awarded his medical degree through the 7-year Honors Program in Medical Education at Northwestern University Medical School in Chicago. He went on to perform his residency in the 7-year Advanced Clinical Scholars Program in Otolaryngology-Head & Neck Surgery at Washington University Medical School in St. Louis, completing a 2-year Plastic Surgery Research Fellowship as well. His training culminated with a prestigious fellowship in Facial Plastic & Reconstructive Surgery at the University of Minnesota School of Medicine.
Dr. Brenner’s cosmetic facial plastic surgery clinic specifically addresses cosmetic treatment of the face, head and neck. He specializes in nasal reshaping surgery (rhinoplasty), cosmetic eyelid surgery, facelift surgery, forehead and brow lift surgery, necklift, scar revision, and ear reshaping, as well as nonsurgical anti-aging facial treatments, such as botox and filler injections.
Dr. Brenner’s reconstructive facial plastic surgery clinic focuses on treatment of structural deformities of the face and neck. He has experience in surgery to improve nasal breathing, cosmetic closure of defects from skin cancer, treatment of facial paralysis, facial trauma, head and neck cancer, with expertise in parotid and thyroid surgery.
Dr. Brenner has held leadership positions in the American Academy for Facial Plastic & Reconstructive Surgery, the American Academy of Otolaryngology-Head & Neck Surgery, and the American Medical Association. He has received several national distinctions for his pioneering research on nerve regeneration. He has lectured widely and authored over 50 articles, book chapters and research grants related to facial plastic surgery. He also participates in Face to Face,a humanitarian program for domestic violence victims and with international outreach.
To make an appointment with Dr. Brenner, please call SIU Healthcare at 217-545-6099.
www.siumed/edu/surgery/otolaryngology
LICENSURE:
United States Medical Licensing Examination, Steps I, II, & III
American Board of Otolaryngology
Missouri Permanent License
Minnesota Permanent License
Illinois Permanent license
Illinois Controlled Substance and Narcotic Certificate
National Provider Identifier (NPI) number
ACLS Cert. 2008 (exp 2/2010)
ATLS Cert 2006 (exp 11/09)
EDUCATION:
09/92-06/95 Northwestern University, Evanston IL
Honors Program in Medical Education
B.A., Psychology, College of Arts & Sciences, 1995
07/95-06/00 Northwestern University School of Medicine (NUMS), Chicago, IL
M.D, Northwestern University School of Medicine, 2000
(Included NIH-funded research year at the medical school 07/97-06/98)
POSTGRADUATE TRAINING
07/00-06/01 Internship, Department of Surgery, Washington University School of Medicine, Saint Louis, MO
07/01-06/03 Postdoctoral Research Fellow (NIH T32 DC 0022-15)
Research Mentor: Susan E. Mackinnon, M.D., FACS
Nerve Reconstruction for Peripheral and Cranial Nerve Injury
Division of Plastic Surgery & Department of Otolaryngology
07/03-06/07 Clinical Resident, Advanced Clinical Scholars Program in Otolaryngology
Washington University School of Medicine, Saint Louis, MO
07/07-06/08 American Academy of Facial Plastic & Reconstructive Surgery Fellow University of Minnesota School of Medicine
Fellowship Director: Peter A. Hilger, M.D.
Academic Appointment: Instructor, Department of Otolaryngology
07/08-Present Adjunct Clinical Faculty, Department of Otolaryngology
Division of Facial Plastic & Reconstructive Surgery
University of Minnesota School of Medicine
09/08-Present Assistant Professor, Department of Surgery, Division of Otolaryngology
Southern Illinois University School of Medicine
Facial Plastic & Reconstructive Surgeon
(Memorial Medical Center & Saint John’s Hospital)
EDITORIAL BOARD/ LEADERSHIP POSITIONS
2007-2008 AAFPRS Research Committee Panel
2007-2008 AAFPRS Regulatory and Socioeconomic Affairs Committee
2007-2008 Delegate, SUO Meeting for Section for Residents & Fellows
2006-2007 American Medical Association Delegate to Section for Residents and Fellows
1999-2000 Senior Editor, Journal of the American Medical Association – Student Section
1998-1999 Assoc. Editor, Journal of the American Medical Association – Student Section
1996-1997 Chair, Youth Intervention Committee of American Cancer Society of Chicago
1995-1996 Vice Chair, Youth Intervention Committee, American Cancer Society, IL
1995-1996 Vice Chair, Northwestern Chapter of the American Medical Association
1995-1996 Co-Editor, Mednotes, Northwestern University Medical School notes service
1994-1995 Executive Board Co-Chair, Students Working Against Poverty, Evanston, IL
HONORS AND AWARDS (EXCLUDING GRANT AWARDS)
2008 THANC Foundation Scholarship for April 2008 Conference (NY,NY)
2007 1st prize AO North America Craniomaxillofacial competition (Minneapolis, MN)
2007 THANC Comprehensive Mgmt of Head & Neck Ca Scholarship (NY, NY)
2007 American Academy of Otolaryngology – Head & Neck Surgery Travel Award
2006 1st prize Walter Work Award Triological Middle Section (San Diego, CA)
2006 American Academy of Otolaryngology – Head & Neck Surgery Travel Award
2006 Triological Middle Section Travel Award
2006 Temporal Bone Dissection PGY-4 Washington University co-winner, tied
2005 Michael Paparella Research Award 24th Ogura Lectureship
2004 Outstanding Nerve Paper for overall highest scored paper submitted to ASPN meeting
2004 1st prize Resident Paper American Society for Peripheral Nerve (Palm Springs, CA)
2003 1st prize Resident Paper WUMS Plastic Surgery Research (St. Louis, MO)
2003 1st prize Resident Paper Midwestern Assoc for Plastic Surgery (Chicago, IL)
2002 1st prize Investigator paper, PSEF National Essay Contest
2000 Johnson F. Hammond, MD, Memorial Scholarship for Medical Journalism
1999 1st prize Alpha Omega Alpha National Essay Contest
1995 Teagle Foundation Merit Scholarship award ($32,000)
FACIAL PLASTIC SURGERY FELLOWSHIP 2007-2008
Aesthetic surgery training and Functional Rhinoplasty
• Cosmetic Rhinoplasty (endonasal, external, rib graft) and aesthetic nasal reconstruction
• Upper and Lower Blepharoplasty (transconjunctival, skin-muscle flap, etc)
• Rhytidectomy (deep plane, SMAS plication, and skin only facelift)
• Necklift and corset platysmaplasty for platysmal banding
• Brow lift (endoscopic and open) and facial implants
• Skin resurfacing (chemical peels, dermabrasion)
• Scar Revision (geometric broken line, w-plasty, z-plasty, m-plasty, v to y)
• Non-surgical facial rejuvenation techniques (fillers and paralytics/Botox)
• Revision Rhinoplasty & Reconstructive Rhinoplasty
• Otoplasty (antihelical fold Mustarde technique, conchal excess for prominent ears)
Moh’s Defect Reconstruction (Repair after resection of cutaneous facial malignancy)
• Advancement, rotation, and Transposition flaps
• Melolabial, bilobe, paramedian forehead, island, rhombic, dorsal nasal flaps
• Lip Reconstruction (mucosal advancement, Abbe, Karapanzik, myomucosal flaps
• Eyelid reconstruction (Tarsoconjunctival/Hughes flap)
• Z-plasty (classic, composite, double opposing, planimetric, unequal triangle z-plasty)
• Cervicofacial advancement flaps, pedicled flaps and microvascular techniques
Craniomaxillofacial
• Maxillofacial trauma services at the University of Minnesota and affiliated hospitals
provided exposure to as many as 100 major maxilla-facial injuries per year.
• Reconstruction of Minneapolis I-35 Bridge collapse pts (Hennepin County Med Ctr)
• LeForte I, II, & III facial fracture, mandibular fracture, NOE, orbital blowout zygoma).
• Soft tissue reconstruction of complex facial laceration of lip, ear, nose, face
• Cleft lip repair (Millard Rotation-Advancement, Triangular Flap/ Randall Tennyson)
• Cleft palate repair (double reverse z-plasty, Wardill-Kilner,von Langenback techniques)
• Speech Surgery (sphincter pharyngoplasty and posterior pharyngeal flap)
• Microtia Reconstruction (costochondral rib graft)
Facial nerve rehabilitation for facial paralysis
• Asymmetric facelift (e.g. for Bell’s Palsy)
• Sub-Orbicularis Oculi Fat pad facelift (“SOOF lift”)
• Orthodromic temporalis tendon transfer for complete paralysis
• Paralytic ectropion repair
• Oculoplastic reconstruction (lateral tarsal strip, posterior lamellar graft, ptosis repair)
• Nasal airway reconstruction for internal/external nasal valve collapse
• Neurorrhaphy and cross facial nerve grafting
• Adjuvant therapy with fillers and paralytics
GRANT FUNDING HISTORY
Principal Investigator
1993 Howard Hughes Research Fellowship Stipend $2,500
“Characterization of Transcription Factors mediating Eukaryotic
Gene Expression”
1996 Alpha Omega Alpha Research Fellowship Grant $3,000
“Neurotoxicity Associated with Convection-Enhanced Delivery
of Ara-C to brain.”
1996 Northwestern University Medical School Research Grant $2,500
“Rodent model of Convection-Enhanced Delivery of Cytosine
Arabinoside for Progressive Multifocal Leukoencephalopathy”
2002 Plastic Surgery Educational Foundation Research Grant $4,000
“Anatomy of Nerve Regeneration After End-to-Side
Neurorrhaphy”
2002 American Society for Surgery of the Hand Grant $14,491
“Stacked End-to-Side Nerve Repairs for Complex Nerve
Injuries”
2002 American Laryngological, Voice, Research and Education Grant $9,988
“Conduit-based Methods to Enhance Nerve Regeneration”
2003 Plastic Surgery Educational Foundation Research Grant $4,969
“Molecular Basis for the Neuroregenerative Effects of FK-506)
(pilot study)
2006 John Q. Adams $1,500
Center for the History of Otolaryngology-Head & Neck Surgery
“Sir Charles Bell and the History of Facial Nerve Paralysis”
2008 American Academy of Facial Plastic & Reconstructive Surgery $15,000
AAO-HNSF/CORE Bernstein Investigator Development Award
“Cutaneous Innervation & Microcirculation as Predictors of Wound
Healing”
Co-Investigator
2003 American Society for Surgery of the Hand Grant; co-investigator $9,930
“Determinants of Motor Neuron Pathway Specificity”
2004 Barnes-Jewish Hospital Foundation Grant; co-investigator $35,000
“Molecular Basis for the Neuroregenerative Effects of FK-506”
Stipends/Support from Federal Funding (Acquired by Faculty)
1997-1998 NIH Training Grant Stipend (Northwestern University; 1 yr) $11,500
Subtractive hybridization with differential screening was applied to the gerbil cochlea (acknowledgement in Zheng J. Shen W. He DZ. Long KB. Madison LD. Dallos P. Prestin is the motor protein of cochlear outer hair cells. Nature. 405(6783):149-55, 2000).
2001-2003 NIH T32 DC 0022-15 Grant Stipend (Washington University; 2yrs) $80,000
Nerve injury was investigated in a variety of experimental paradigms with emphasis on reconstructive, pharmacologic, immunomodulatory, and tissue engineering strategies to optimize nerve regeneration. Supplemental nonfederal funding is detailed in above sections.
PROFESSIONAL SOCIETY MEMBERSHIPS
American Academy for Facial Plastic & Reconstructive Surgery (2005-present)
American Academy of Otolaryngology -- Head & Neck Surgery (2000-present)
American Medical Association (1995-2000; 2005-present)
American Medical Association PAC (2006-present)
American Physician Scientist Association (2008-present)
Sir Charles Bell Society (2006-present)
Triological Society (2006-present)
American College of Surgeons (2006-present)
RESEARCH INTERESTS:
Nerve regeneration, axonal guidance, tissue engineering, functional recovery, wound healing, facial nerve paralysis, nerve reconstruction, facial reanimation, rhinoplasty
TEACHING/ MENTORING EXPERIENCE
2001-2006: Medical student research teaching under direction of Dr. Mackinnon
-Megan A. Denzel (2004) - Katherine E. Schwetye (2004)
- David H. Kawamura, M.D. (2002) - Janakie Singham, M.D. (2003)
- Jason D. Keune (2003) - Ian R.P. Sunderland, M.D. (2003)
- Annie C. Lee, M.D. (2001) - J Clinton Walker, M.D. (2002)
- Brendan M. Lloyd (2005) - Vivian M. Yu, M.D. (2001)
- Vinaya K. Puppala (2005) - Ryan Luginbuhl (2006)
- Elizabeth Whitlock (2007-8)
2003-2008: Participation in Didactic Lecture Series and Conferences
• Evaluation of Profound Hearing Loss: Cochlear Implantation Candidate Evaluation (October 29, 2003)
• Otologic Manifestations of Systemic Disease: Mycobacterial Infections, Fungal Infections and Immunodeficiency (December 17, 2003)
• Evaluation of Facial Nerve Paralysis: Facial Nerve Anatomy, Monitoring, & Grading (November 19, 2004)
• Benjamin Senturia Lecutureship Resident Case Presentation (October 5, 2005)
• Otosclerosis: Diagnosis & Management (November 30, 2005)
• Complications of Suppurative Middle Ear Disease (March 22, 2006)
• Airway Management: Evaluation and Diagnosis, Algorithms, and Surgical Airway
(Orientation course June 26, 2006)
• Trauma Management: Mandible, Midface, Orbital, Frontal Sinus, and blunt and penetrating neck trauma (Orientation course June 26, 2006)
• Craniofacial Approach to the Skull Base (Washington U. Grand Rounds; May 30, 2007)
• How to Launch your Career as a Physician-Scientist (Physician Scientist Conference Seminar, May 29, 2007)
• Facial Nerve Reanimation: A Clinical and Research Perspective (Southern Illinois University School of Medicine Resident Conference, January 22, 2008)
1999-2000: Medical Student JAMA collaborator for launch of AMA Virtual Mentor (an interactive, web-based forum designed to promote ethical development of medical students, residents, and young physicians during training)
Available at: www.virtualmentor.org
1996-1997: Co-Director Eckenhoff Memorial Surgical Preceptorship
1991-1992: Co-Director Organization of Student Tutors
CONFERENCE PROCEEEDINGS
1. Brenner MJ, Mackinnon SE, Jensen JA, Hunter DA. Anti-CD40 ligand antibody promotes nerve regeneration in mouse tibial nerve allografts. 47th annual meeting of the Plastic Surgery Research Council, to be held April 17-20, 2002 in Boston, Massachusetts (poster #455).
2. Jensen JE, Lowe JB III, Brenner MJ, Mackinnon SE, Hunter DA. Anti CD40 Ligand Antibody Permits Regeneration through Peripheral Nerve Allografts in a Non-Human Primate Model. 47th annual meeting of the Plastic Surgery Research Council, to be held April 17-20, 2002 in Boston, Massachusetts (poster #455).
3. Lee AC, Yu VM, Lowe JB III, Brenner MJ, Mackinnon SE, Sakiyama Elbert SE. Controlled release of Nerve Growth Factor enhances sciatic Nerve Regeneration. 47th annual meeting of the Plastic Surgery Research Council, to be held April 17-20, 2002 in Boston, Massachusetts
4. Brenner MJ, Hoistad D, Hain TC. Prevalence of thyroid dysfunction in patients with Meniere’s disease. Presented at: Association for Research in Otololaryngology (St. Petersberg, Florida) 2000.
5. Brenner MJ, He ZZ, Long K, Zheng J, Dallos P, Madison LD. Regulation of gene expression by thyroid hormone in the developing organ of Corti. Presented at: Molecular Biology of Hearing Conference (Washington DC) 1998.
6. Brenner MJ, Tong D, Rothholtz V, Groothius D, Levy RM. Neurotoxicity associated with convection enhanced delivery of Ara-C to brain. Presented at: AWA/NUMS Conference (Chicago, IL) 1996 & American Association of Neurological Surgeons Conference (Philadelphia, PA) 1997
7. Brenner MJ, Dvali LT, Hunter DA, Mackinnon SE. Motor Axonal Regeneration in an End-to-side Model. 41st Annual Scientific Meeting of the Midwestern Association for Plastic Surgery (Chicago, IL), April 5th-6th 2003. First Prize Resident Paper.
8. Fox IK, Brenner MJ, Kawamura DH, Mackinnon SE, Yu VM, Hunter DA. Effect of FK506 on Delayed versus Immediate Repair of Nerve Transection Injury. American College of Surgeon Missouri Chapter Meeting, Lake of the Ozarks, MO, June 13-15th, 2002. First Prize Resident Paper.
9. Sunderland IRP, Brenner MJ, Singham J, Hunter DA, Mackinnon SE. Effect of Tension on Nerve Regeneration in Rat Sciatic Nerve Transection Model. 48th annual meeting of the Plastic Surgery Research Council meeting in Boston, MA, April 23-26, 2003.
10. Fox IK, Brenner MJ, Kawamura DH, Mackinnon SE, Yu VM, Hunter DA. Effect of FK506 on Delayed versus Immediate Repair of Nerve Transection Injury. 48th annual meeting of the Plastic Surgery Research Council meeting in Boston, MA, April 23-26, 2003.
11. Michael J. Brenner, M.D.., James B. Lowe, III, M.D., Ida K. Fox, M.D., Terence M. Myckatyn, M.D., Daniel A. Hunter, R.A., Thomas H.H. Tung, M.D., Ramsay A. Ellis, M.D., John N. Jensen, M.D., Susan E. Mackinnon, M.D. Immunomodulatory and Neuroregenerative Strategies for Nerve Allotransplantation: Role of Calcineurin Inhibition and Costimulatory Blockade (WUSM Plastic Surgery Conference, June 2003) First Prize Resident Paper.
12. Michael J. Brenner, M.D. et al Immunomodulatory and Neuroregenerative Strategies for Nerve Allotransplantation (WUSM Dept of Otolaryngology Ogura Day presentation, June 2003)
13. Michael J. Brenner, M.D.., John N. Jensen, M.D., James B. Lowe, III, M.D., Terence M. Myckatyn, M.D., Ida K. Fox, M.D., Daniel A. Hunter, R.T., Susan E. Mackinnon, M.D. Use of Anti-CD40L mAb for Nerve Allotransplantation in Nonhuman Primates: Role of Antigen Load and Permanence of Immunomodulation, ASPN January 2004 Outstanding Nerve Paper (overall highest scored paper submitted to ASPN meeting)
14. Michael J. Brenner, M.D.., James B. Lowe, III, M.D., Susan E. Mackinnon, M.D., Michael Darcy, M.D., James Duncan, M.D., Ida K. Fox, M.D., Daniel A. Hunter, R.A., and Patrick M. Wood, Ph.D. Effect of Schwann Cells and Donor Antigen on Regeneration Across Long Nerve Allografts. American Society for Peripheral Nerve. January 2004. First Prize Resident Paper
15. Fox IK, Schwetye KE, Brenner MJ, Keune JD, Yu JW, Hunter DA, Wood PM, Mackinnon SE. The Effect of Prolonged Cold Preservation & Schwann Cell Injection on Nerve Allografts (Plastic Surgery Research Council, Philadelpia, PA, June 2004). First Prize Resident Paper.
16. Brenner, MJ. Role of Donor Nerve injury in promoting regeneration through end-to-side nerve Repairs.
June 10, 2005 24th Annual Ogura Lectureship Saint Louis, MO. Michael Paparella Resident Research Award
17. Brenner MJ, Mackinnon SE, Rickman SR, Tung TH, Hunter DA. Immunomodulatory Interactions of Anti-CD40L mAb and FK506 in Nerve Allotransplantation. ASPN. Tucson, AZ #5373. January 2006
18. Brenner MJ, Hess JR, Dvali LT, Hunter DA, Myckatyn TM, Mackinnon SE. Role of Age and Donor Nerve Injury as Determinants of Regeneration across End-to-Side Nerve Repairs. ASPN. Tucson, AZ #5376. January 2006
19. Nicholas CM, Luginbuhl RD, Lloyd BM, Brenner MJ, Rocque B, Hunter DA, Mackinnon SE. Use of Modality Matched Autogenous Nerve Material in Peripheral Nerve Repair with Conduits. ASPN. Tucson, AZ #5426. January 2006
20. Moradzadeh A, Hess JR, Brenner MJ, Myckatyn TM, Hayashi A, Hunter DA, Mackinnon SE. The effects of fascicle quantity and composition on nerve regeneration across a mixed peripheral nerve gap. Association for Reconstructive Microsurgery. Tucson, AZ #5558. January 2006.
21. Brenner MJ, Hess JR, Hayashi A, Hunter DA, Mackinnon SE. Reconstruction of Motor Nerve Defects with Sensory Nerve Grafts Inhibits Nerve Regeneration in a Rodent Model/ Accepted to midsection triological meeting February 2006, San Diego, CA (accepted to meeting). First Prize Walter Work Award for Basic Science/ Triological Middle Section.
22. Brenner MJ, Mackinnon SE, Mendez AB, Jensen JN, Hunter DA, Myckatyn TM. The “Blow-Through Effect”: Role of Timing in Neuroregeneration. AAOHNS Academy Meeting, 2006, Toronto ON, CA.
23. Brenner MJ, Mackinnon SE, Mendez AB, Hunter DA, Myckatyn TM. Defining the Window of Opportunity for Histological and Functional Assessment after Nerve Reconstruction. James Barrett Brown Plastic Surgery Lectureship and Resident Research Symposium. June 2006. Saint Louis, MO.
24 Hunter DA, Moradzadeh A, Whitlock EL, Brenner MJ, Myckatyn TM, Wei CH, Tung THH, Mackinnon SE. Binary Image Analysis for Comprehensive Quantitative Assessment of Peripheral Nerve. ASPN January 13-14th, 2007. Rio Grande, Puerto Rico.
25. Moradzadeh A, Whitlock EL, Brenner MJ, Hunter DA, Mackinnon SE. Ropivacaine-Induced Nerve Injection Injury in the Rodent Model (Abstract #287), 53rd Annual Meeting of PSRC, Springfield, Illinois, May 28-31, 2008
26. Moradzadeh A, Brenner MJ, Whitlock EL, Luciano JP, Tong AY, Hunter DA, Myckatyn TM, Mackinnon SE. Effects of bipolar electrocautery on regeneration of rat sciatic nerve. American Academy of Otolaryngology – Head & Neck Surgery, Chicago, IL, Sept 21-24, 2008
CONFERENCES AND COURSES ATTENDED
1. Association for Research in Otolaryngology, Coral Gables, FL, 1997
2. Ogura Lectureship & Resident Research Day, St. Louis, MO 2001- 2005
3. Plastic Surgery Research Council Boston, MA, 2002
4. Plastic Surgery Resident Research Day St. Louis, MO, 2002-2004, 2006
5. Plastic Surgery Educational Foundation/AAPS/ASPS meeting, Dallas, Tx, 2003
6. Midwestern Association for Plastic Surgery, Chicago, IL 2003
7. American Society for Peripheral Nerve, Palm Springs, California January 2004
8. Washington University Medical School Grant-writing Series, St. Louis, MO, 2004
9. Free Tissue Transfer for Major Ablative Defects of the Head & Neck, St. Louis, 2005
10. AO-ASIF Craniomaxillofacial Plating Conference Stl, MO May 2005
11. Midwestern Update in Endoscopic Sinus Surgery St. Louis, MO, August, July 2005
12. AAFPRS annual meeting& Essentials Course, Los Angeles, CA, September 2005
13. Advanced Clinical Scholars/ Physician-Scientist Meetings, St. Louis, MO, 2000-2005
14. Challenges and Advances in Craniomaxillofacial Trauma and Reconstruction
Focus: Cadaver Practical Workshop, St. Louis, MO, April 1-2 2006
15. Advances in Cosmetic Blepharoplasty, Brow & Midface Lift, St. Louis MO [Staff]
J. Holds, MD & M. Hartstein, MD & P. Custer, MD-July 28-29, 2006
16. AAOHNS Conference, Toronto, ON, Sept 17-20 2006
17. AO-ASIF Principles of Craniomaxillofacial Surgery, Toronto, ON, Sept 16, 2006
18. Otolaryngology Historical Society Meeting, Toronto, ON, Sept 17, 2006
19. AAFPRS annual meeting, Toronto, ON, Sept 13-17, 2006
20. Section for Residents & Fellows AAO Annual Sessions, Toronto, ON, Sept 18-19
21. Free Tissue Transfer for Major Ablative Defects of the Head & Neck, St. Louis, 2006
22. Endoscopic & Minimally Invasive Surgery of the Aging Face, St Louis, Nov 17-18
23. 17th Annual Course on Controversies in the Management of Thyroid and Parathyroid Diseases and Comprehensive Management of Advanced Head and Neck Cancer, March 17-23, 2007 at Beth Israel Medical Center in New York, NY
24. Endoscopic Sinus Practicum, May 17-18, Saint Louis, MO
25. Techniques in Endoscopic Sinus Surgery, a hands-on cadaver course, Practical Anatomy & Surgical Education facility, June 9, 2007, Saint Louis, MO
26. Principles of Treatment of Craniomaxillofacial Trauma AO North America, Minneapolis, MN. Aug 17-19, 2007, Minneapolis, MN 55409.
27. AAO-HNS Annual Meeting, Washington D.C. Sept 15-19, 2007
28. AAFPRS Annual Meeting, Washington D.C. Sept 17-21, 2007
29. Free Tissue Transfer for Major Ablative Defects of the Head& Neck, St. Louis, 2007
30. Society of University Otolaryngologists, Washington D.C. Nov 2-4, 2007
31. AAFPRS Rejuvenation of the Aging Face, April 6-9, 2008, SF, CA
32. AO NorthAmericaMultidisciplinary Management of Head and Neck Cancer 2008 Apr 10 2008, Tarrytown, NY.
33.AO North AmericaChallenges and Advances, Focus: Hands-On Course in Free Flap Reconstruction of Head and Neck Defects Apr 11-13, 2008, Tarrytown, NY.
34. Plastic Surgery Research Council Meeting, Springfield, IL, May 28-31 2008
JOURNALS ARTICLES – PUBLISHED / IN PRESS
- Brenner MJ. The Curative Paradigm in Medical Education: Striking a Balance Between Caring and Curing. The Pharos of Alpha Omega Alpha Honor Medical Society. 1999; 62: 40-45. 1st prize: Alpha Omega Alpha National Essay Contest
- Brenner MJ. Environmental medicine: From the concert hall to the barracks. Journal of the American Medical Association: 1999; 281(17): 1656.
- Brenner MJ. The new Atlantis and the frontiers of medicine. Journal of the American Medical Association:2000; 283:2296, 2000
- Brenner MJ, Tung T, Jensen JN, Mackinnon SE. Spectrum of complications of chronic immunosuppression: Is the time right for hand surgery. Journal of Bone & Joint Surgery. 84-A(10):1861-70, 2002.
- Jensen JN, Tung THH, Mackinnon SE, Brenner MJ, Hunter DA. Use of anti-CD40 ligand monoclonal antibody as anti-rejection therapy in a murine peripheral nerve allograft model. Microsurgery. 2004;24(4):309-15.
- Brenner MJ, Mackinnon SE, Tung TH, Myckatyn TM, Hunter DA. Anti-CD40 ligand monoclonal antibody induces a permissive state, but not tolerance, for murine peripheral nerve allografts. Experimental Neurology. 2004;186 (1):59-69.
- Ellis RA, Brenner MJ, Mackinnon SE, Hunter DA. Use of the mixed lymphocyte reaction to identify sub-immunosuppressive FK-506 levels in mice. Microsurgery. 23(3):276-82, 2003.
- Walker JC, Brenner MJ, Mackinnon SE, Winograd JM, Hunter DA. Role of Perineurial Window Size in End-to-Side Nerve Repairs: Implications for Nerve Regeneration, Blood-Nerve Barrier Integrity, and Functional Recovery. Journal of Neurotrauma. 2004 Feb;21(2):217-27.
- Brenner MJ, Kawamura D, Fox IA, Mackinnon SE,Yu VA, Hunter DA. Delay in repair of nerve transection injury diminishes the neuroregenerative effects of FK506 therapy. Laryngoscope. 2004 Mar;114(3):570-6.
- Lee AC, Yu VM, Lowe JB III, Brenner MJ, Hunter DA, Mackinnon SE, Sakiyama Elbert SE. Controlled release of nerve growth factor enhance sciatic nerve regeneration. Experimental Neurology. 184(1):295-303, 2003.
- Brenner MJ, Jensen JN, Lowe JB III, Fox IK, Myckatyn TM, Hunter DA, Mohanakumar T, Mackinnon SE. Anti-CD40 ligand antibody permits regeneration through peripheral nerve allografts in a non-human primate model. Plastic & Reconstructive Surgery.2004 Dec;114(7):1802-14; discussion 1815-7.
- Brenner MJ, Lowe JB, Mackinnon SE, Sen SK, Hunter DA. Wood PM. Effects of Schwann cells and donor antigen on long-nerve allograft regeneration. Microsurgery. 2005;25(1):61-70
- Brenner MJ & Neely JG.Approaches to Grading Facial Nerve FunctionSeminars in Plastic Surgery.Issue01 Vol18. February2004
- Myckatyn, TM , Brenner M, Hussussian, CJ, Chao, CK, Hunter DA, Mackinnon SE The Effects of External Beam Radiation on Nerve Regeneration in Rat Tibial Nerve Crush, Transection, and Isograft Models. Laryngoscope. 2004; 114(5):931-8.
- Brenner M, Hoistad DL, Hain TC. Prevalence of thyroid dysfunction in patients with Meniere's disease. Archives of Otolaryngology -- Head & Neck Surgery . 2004 Feb;130(2):226-8.
- Dvali L, Brenner MJ, Mackinnon SE. The Surgical Workforce Crisis: Rising to the Challenge of Caring for an Aging America. Plastic & Reconstructive Surgery. 2004 Mar;113(3):893-902.
- Sunderland IRP, Brenner MJ, Singham J, Hunter DA, Mackinnon SE.Effect of Tension on Nerve Regeneration in Rat Sciatic Nerve Transection Model. Annals of Plastic Surgery. 2004 Oct;53(4):382-387.
- Nichols CM, Brenner MJ, Fox IK, Tung TH, Hunter DA, Rickman SR, Mackinnon SE: Effect of motor versus sensory nerve grafts on peripheral nerve regeneration. Experimental Neurology.190, 347-355, 2004.
- Sen SK, Lowe JB III, Brenner, MJ, Hunter RT, Mackinnon SE. Assessment of the immune response to dose of nerve allografts. Plastic & Reconstructive Surgery. 2005;115(3):823-30.
- Jensen JN, Brenner MJ, Tung TH, Hunter DA, Mackinnon SE. Effect of FK506 on Peripheral Nerve Regeneration through Long Grafts in Inbred Swine. Annals of Plastic Surgery 2005 Apr;54(4):420-7.
- Brenner MJ, Mackinnon SE, Rickman SR, Jaramillo A, Tung TH, Hunter DA, Mohanakumar T. FK506 and anti-CD40 Ligand in Peripheral Nerve Allotransplantation. Restorative Neurology & Neuroscience. 2005;23(3-4):237-49.
- Kawamura DH, Hadlock TA, Fox IK, Brenner MJ, Hunter DA, Mackinnon SE. Regeneration Through Nerve Isografts is Independent of Nerve Geometry. Journal of Reconstructive Microsurgery. 2005 May;21(4):243-9.
- Fox IK, Schwetye KE, Brenner MJ, Keune JD, Yu JW, Hunter DA, Wood PM, Mackinnon SE. The Effect of Prolonged Cold Preservation & Schwann Cell Injection on Nerve Allografts. Microsurgery. 2005;25(6):502-7.
- Brenner MJ, Mackinnon SE. End-to-side nerve graft repair based on synergistic peripheral terminal motor branches: Investigation in a non-human primate model. [Invited Commentary] European Surgery.2006;37 (6): 317-319.
- Brenner MJ, Hess JR, Myckatyn TM, Hayashi A, Hunter DA, Mackinnon SE. Repair of motor nerve gaps with sensory nerve inhibits regeneration in rats. Laryngoscope. 2006 Sep;116(9):1685-92. Hess JR. Brenner MJ. Fox IK. Nichols CM. Myckatyn TM. Hunter DA. Rickman SR. Mackinnon SE
- Hess JR, Brenner MJ, Myckatyn TM, Hunter DA, Mackinnon SE. Influence of Aging on Regeneration in End-to-Side Neurorrhaphy. Annals of Plastic Surgery. 2006; 57(2):217-222.
- Keune JD, Brenner MJ, Schwetye KE, Yu JW, Fox IK, Hunter DA, Mackinnon SE. Temporal Factors in Peripheral Nerve Reconstruction with Suture Scaffolds: An Experimental Study in Rodents. Restorative Neurology & Neuroscience. 2006; 24: 181-190.
- Hess JR. Brenner MJ. Fox IK. Nichols CM. Myckatyn TM. Hunter DA. Rickman SR. Mackinnon SE. Use of cold-preserved allografts seeded with autologous Schwann cells in the treatment of a long-gap peripheral nerve injury. Plastic & Reconstructive Surgery. 2007; 119(1):246-59.
- Brenner MJ, Dvali L, Hunter DA, Myckatyn TM, Mackinnon SE. Motor Neuron Regeneration Through End-to-Side Repairs is a Function of Donor Nerve Axotomy. Plastic & Reconstructive Surgery. 2007; 121: 1-9
- Lloyd BM, Luginbuhl RD, Brenner MJ, Rocque BG, Tung THH, Myckatyn TA, Hunter DA, Mackinnon SE. Use of Motor Nerve Material in Peripheral Nerve Repair with Conduits. Microsurgery. 2007; 27(2):138-45.
- Brenner MJ, Goebel JG, Wippoled FJ2nd. Insufficient skull thickness as limiting factor in Bone-Anchored Hearing Aid placement BAHA. Otol Neurotol. 2007; 28(6):865-866.
- Brenner MJ, Floyd L, Collins SL. Speech prosthesis aspiration in the post-laryngectomy patient. Annals of Otology, Rhinology, & Laryngology. 2007 Dec;116(12):882-6..
- Hunter DA, Moradzadeh A, Whitlock EL, Brenner MJ, Myckatyn TM, Wei CH, Tung TH, Mackinnon SE. Binary imaging analysis for comprehensive quantitative histomorphometry of peripheral nerve. Journal of Neuroscience Methods. 2007;166(1):116-24.
- Brenner MJ, Perrin RJ, Uppaluri R, Zipfel GJ, Lewis, JS. Pathology Quiz Case 2 –Atypical Meningioma with Clear Cell Features (World Health Organization [WHO] Grade II) Archives of Otolaryngology – Head & Neck Surgery. 2008 Apr;134(4):447-9
- Brenner MJ, Moradzadeh A, Mendez AB, Myckatyn TM, Jensen JN, Hunter DA, Mackinnon SE. Role of timing in assessment of peripheral nerve regeneration. Microsurgery. 2008;28(4):265-72..
- Brenner MJ, Haughey BH, Lewis JS. Pathology Quiz Case – Alveolar Rhabdomyosarcoma. Archives of Otolaryngology–Head & Neck Surgery. In press
MANUSCRIPTS IN PREPARATION OR SUBMITTED
- Whitlock EL, Brenner MJ, Moradzadeh A, Fox IK, Hunter DA, Mackinnon SE. Ropivacaine-induced nerve injection injury in the rodent model. Target: Plastic & Reconstructive Surgery
- Brenner MJ, Myckatyn TM, Hunter DA, Mackinnon SE. Assessment of donor nerve injury after stacked end-to-side nerve repair. Target: Microsurgery
- Brenner MJ, Neely JG. Late progression of labryinthitis ossificans following cryptococcal meningitis in a cochlear implant patient. Target: Otol Neurotol
- Sakiyama-Elbert SE, McKee A, Ahmad S, Soman N, Lowe III JB, Brenner MJ, Fox IK, Hunter DA, Tung THH, Mackinnon SE. Effect of Sciatic Nerve Transection Injury on Gene Expression in Ventral Horn, Dorsal Root Ganglia and Sciatic Nerve.
- Brenner MJ, Sidman J. Triangular flap technique for repair of unilateral cleft lip deformity.
- Moradzadeh A, Brenner MJ, Whitlock EL, Luciano JP, Tong AY, Hunter DA, Myckatyn TM, Mackinnon SE. Effects of bipolar electrocautery on regeneration of rat sciatic nerve. Target: Otolaryngology – Head & Neck Surgery
BOOK CHAPTERS
Brenner MJ and Hilger PA. Late wound management (scar revision), Chapter 41. Eds. Goldberg AN, Lee C, & Murr AH. Head and Neck Trauma. Informa Healthcare USA, Inc. New York. 2008 (in press)
In preparation: Myckatyn TM and Brenner MJ. Facial Nerve Injury: Ed. Mackinnon SE. Peripheral Nerve Surgery. Thieme. New York.
In Preparation: Brenner MJ and Hilger PA. Grafting in Rhinoplasty. Facial Plastic Surgery Clinics of North America. Ed. Minas Constantinides Elsevier. February 2009 issue.
In Preparation: Brenner MJ and Hilger PA. Thin Skin Rhinoplasty. In Rhinoplasty. Ed Calvin Johnson
PERIODICALS
1. Brenner MJ. Understanding hearing loss in the elderly. American Journal of Ethics and Medicine. 1998; 6:14-16.
2. Brenner MJ. Hearing help [letter]. US News & World Report. June 21, 1999; 8.
3. Brenner MJ. Deaf, not dumb [letter]. The New Yorker. April 4, 1998; 7.
The presentations corresponding to these awards are detailed under “Conference Proceedings,”
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