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Kathleen CampbellKathleen C.M. Campbell, Ph.D.
Department of Surgery
Division of Otolaryngology - Head and Neck Surgery, Audiology Research

 

 

Education/Training

South Dakota State University B.A. 1973 Communication/Education
University of South Dakota M.A. 1977 Audiology
University of Iowa Ph.D. 1989 Audiology/Hearing Science

Professional Experience

1977-1982 Audiologist II, British Columbia Ministry of Health
1983-1988 Audiologist II, Department of Otolaryngology, University of Iowa
1989-1992 Assistant Professor & Director of Audiology, Division of Otolaryngology, Department of Surgery, Southern Illinois University School of Medicine
1992-1996 Associate Professor & Director of Audiology, Division of Otolaryngology, Department of Surgery, Southern Illinois University School of Medicine
1996-2002 Professor & Director of Audiology, Division of Otolaryngology, Department of Surgery, Southern Illinois University School of Medicine
2003-Present Professor & Director of Audiology Research, Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, Southern Illinois University School of Medicine

Honors and Awards

  • NIH Clinical Investigator Award (K08), 1990
  • NIH James A. Shannon Directors Award, 1997
  • Fellow of the American Speech Language Hearing Association, 2000
  • American Academy of Audiology: Special Presidential Citation for Work Developing National
  • Professional Practice Guidelines and Algorithms, 2001
  • Elected to the National Board of Directors for the American Academy of Audiology, 2001

Selected Recent Bibliography Selected peer-reviewed publications.

  1. Campbell, K.C.M "Letter to the Editor re: Tinnitus and Vertigo (Chole and Parker)
    Archives of Otolaryngology 119, 474, April 1993.
  2. Campbell, K. Reply to Dr. Shea, Annals of Otology, Rhinology, & Laryngology. (Letter to the Editor) 102 (2). 77 January 1993. (Invited)
  3. Campbell, K. Electrocochleographic Findings in Perilymphatic Fistula Seminars in Hearing Vol. 15/1, 22-30. February 1994. (Invited)
  4. Campbell, K., Abbas, P. Electrocochleography with Postural Changes in Perilymphatic Fistula and Meniere's Disease. Journal of the AmericanAcademy of Audiology . Vol. 4. 376-383, November, 1993. (Invited).
  5. Campbell, K.C.M Letter to the Editor re: Tinnitus and Vertigo (Chole and Parker)
    Archives of Otolaryngology 119, 474, April 1993.
  6. Campbell, K. Reply to Dr. Shea, Annals of Otology, Rhinology, & Laryngology. (Letter to the Editor) 102 (2). 77 January 1993. (Invited)
  7. Campbell, K. Electrocochleographic Findings in Perilymphatic Fistula Seminars in Hearing Vol. 15/1, 22-30. February 1994. (Invited)
  8. Campbell, K.C.M, Abbas, P.J. Electrocochleography with Postural Changes in Perilymphatic Fistula: Animal Studies. Annals of Otology, Rhinology, & Laryngology103:474-82. June 1994
  9. Laureano, A., McGrady, M., and Campbell, K. Comparison of Tympanic Membrane Electrocochleography and the Auditory Brainstem Response in Threshold Determination. The American Journal of Otolaryngology. 16 (2):209-215 March 1995. (Selected for Home Study Course, an AAO-HNS publication, section eight, "Otology and Neurotology".)
  10. Campbell, K.C.M. Audiology Curriculum Guidelines for Otolaryngologists. American Journal of Audiology. 4(1):35-36. March 1995.
  11. Campbell, K.C.M, Brady, B.A.. Comparison of 1000 Hz Toneburst and Click Stimuli in Otoneurologic ABR. American Journal of Audiology. 4:55-60. July 1995.
  12. Coburn, K.L., Campbell, K.C.M, Kuhn, M.J., and Moreno, M.A. Electrocorticaland Structural Abnormalities in a Long-term Survivor of Trisomy 13 (Patau's
    Syndrome). American Journal of Audiology. 5(1):35-43. March 1996
  13. Campbell, K.C.M, Naritoku, D. K., Evans, M.S., Hughes, L F.and Rybak, L.P. Is
    Valproic Acid Ototoxic? American Journal of Audiology. 5(3):7-10. November 1996.
  14. Ferraro, J.A., Durrant, J.D., Sininger, Y. S. and Campbell, K. Recommended Guidelines for Reporting AEP Specifications. American Journal of Audiology. 5(3):35-37. November 1996.
  15. Campbell, K.C.M, Rybak, L.P. Sensorineural Hearing Loss and Dyslipidemia. American Journal of Audiology. 5(3):11-14. November 1996.
  16. Campbell, K.C.M, Rybak, L. P., Meech, R. P., and Hughes, L. D-Methionine Provides Excellent Protection from Cisplatin Ototoxicity in the Rat. Hearing Research. 102:90-December 1996.
  17. Meech, Robert P., Campbell, Kathleen C. M., Hughes, Larry P., and Rybak, Leonard P. A Semiquantitative Analysis of the Effects of Cisplatin on the Rat Stria Vascularis. Hearing Research 124:44-59 June 1998.
  18. Campbell, K.C.M Essential Audiology for Physicians (1998) Singular Publishing, San Diego (single author text book)
  19. Campbell, K.C.M, Meech, R.P., Rybak, L.P., Hughes, L.P. D-Methionine Protects Against Cisplatin Damage to the Stria Vascularis. Hearing Research 138:13-28, 1999.
  20. Kovach, Margaret J., Lin, Jing-Ping, Boyadjiev, Simeon, Campbell, Kathleen, Mazzeo, Larry, Herman, Kristin, Rimer, Lisa A., Frank, William, Llewellyn, Barbara, Jabs, Ethylin Wang, Gelber, David and Kimonis, Virginia E. A Unique Point Mutation in the PMP22 Gene is Associated with Charcot-Marie Tooth Disease and Deafness. American Journal of Human Genetics, Vol. 64, May, 1999.
  21. Campbell, K.C.M and Klemens, J. Sudden Hearing Loss and Autoimmune Inner Ear Disease. Journal of the American Academy of Audiology, 11:361-367, 2000 (invited)
  22. Cloven, Noelle Gillette, Re, Alesandra, McHale, Michael, Burger, Robert, DiSala, Philip, Rose, Scott, Campbell, Kathleen C.M., Fan, Hung. Evaluation of D-Methionine as a Cytoprotectant in Cisplatin Treatment of an Animal Model for Ovarian Cancer. AntiCancer Research, 20:4205-4210, 2000
  23. Campbell, Kathleen C.M., Kalkanis, James and Glatz, F. Robert. Ototoxicity: mechanisms, protective agents, and monitoring. Current Opinion in Otolaryngology & Head and Neck Surgery, 8:436-440, 2000 (invited).
  24. Bratt, G., Campbell, K., Cherow, E., Grimes, A. Haskell, G., Higdon, L., McCarthy, P., Noffsinger, D. Center for Hearing and Balanceal Practice Algorithms and Statements. Audiology Today Special Issue, August 2000, pp3-19.
  25. Hatzopoulos, Stavros, Di Stefano, M., Campbell, K.C.M, Falgione, D., Ricci, D., Rosignoli, M., Finesso, M., Albertin, A., Previati, M., Capitani, S. and Martini, A. Cisplatin Ototoxicity in the Sprague Dawley Rat Evaluated by Distortion Product Otoacoustic Emissions. Audiology, 40:253-264, 2001.
  26. Kimonis, V.E., Kovach, M, Campbell, K., Herman, K., Waggoner, B., Gelber, D., and Hughes, L. Anticipation in a Unique Family with Charcot-Marie-Tooth Syndrome and Deafness: Delineation of the Clinical Features and Review of the Literature. American Journal of Medical Genetics, 108:295-303 (2002).
  27. Donnersberger, David R., Campbell, Kathleen C. M., Meech, Robert P., Rybak, Leonard P., Hughes, Larry F., Nanavati, P. J. A Model for Marked Radiation-Induced Hearing Loss. Journal of Burns, (journalofburns.com)
  28. Campbell, Kathleen C.M. Developing Otoprotective Agents for Ototoxic and Noise-Induced Hearing Loss: D-methionine and other compounds. NHCA Spectrum 19(2):12-14, 2002
  29. Blakley, BW, Cohen, JI, Doolittle, ND, Muldoon, LL, Campbell, KC, Dickey, T, Neuwelt, EA. Strategies for Prevention of Toxicity Caused by Platinum Based Chemotherapy: Review and Summary of the Annual Meeting of the Blood-Brain Barrier Disruption Program, Gleneden Beach, Oregon, March 12, 2001. Laryngoscope 112: pp 1997-2001.2002.
  30. Korver, K.D., Rybak, L.P., Whitworth, C., & Campbell, K.C. Round Window Application of D-Methionine Provides Complete Cisplatin Otoprotection. Otolaryngology-Head and Neck Surgery, 126:683-689, 2002.
  31. Kopke, R.D., Coleman, J.K.M., Liu, J., Campbell, K.C.M, and Riffenburgh, R.H. Enhancing Intrinsic Cochlear Stress Defenses to Reduce Noise-Induced Hearing Loss. The Laryngoscope 112:1515-1532, 2002
  32. Klemens, James J., Campbell, Kathleen C. M., Meech, Robert P., Hughes, Larry F., and Somani, Satu. Anti-oxidant Levels Inversely Co-vary with Hearing Loss After Amikacin Treatment. Journal of the American Academy of Audiology: Special Edition on Ototoxicity 14(3):134-143.2003.
  33. Campbell, Kathleen C.M., Larsen, Deb L., Meech, Robert P., Rybak, Leonard P., and Hughes, Larry F. Glutathione Ester But Not Glutathione Protects Against Cisplatin-Induced Ototoxicity in a Rat Model. Journal of the American Academy of Audiology: Special Edition on Ototoxicity 14(3):124-133.2003.
  34. Campbell, Kathleen CM, Kelly, Ellen, Targovnik, Nan, Hughes, Larry F., Van Saders, Claudia, Gottleib, Alice B., Dorr, Mary Beth, Leighton, Anton. Audiologic Monitoring for Potential Ototoxicity in a Phase I Clinical Trial of a New Glycopeptide Antibiotic. Journal of the American Academy of Audiology: Special Edition on Ototoxicity 14(3):157-169.2003.
  35. Campbell, Kathleen CM. Introduction to Oxidative Processes. (brief tutorial) Journal of the American Academy of Audiology: Special Edition on Ototoxicity 14(3):121-123.2003.
  36. Campbell, Kathleen CM, Meech, Robert P., Rybak, Leonard P., Hughes, Larry F., The Effect of D-Methionine on Cochlear Oxidative State with and without Cisplatin Administration: Mechanisms of Otoprotection. Journal of the American Academy of Audiology: Special Edition on Ototoxicity 14(3):144-156.2003
  37. Leighton, A, Gottlieb, AB, Dorr, MB, Jabes, D, Mosconi, G, VanSaders, C, Mroszczak, EJ, Campbell, KCM, Kelly, E. Tolerability, Pharmacokinetics and Serum Bacterial Activity of Intravenous Dalbavancin in Healthy Volunteers._Antimicrobial Agents and Chemotherapy._48(3):940-945, March 2004
  38. Campbell, Kathleen CM, Bromate Induced Ototoxicity. (2006) _Toxicology._ 221(2-3):205-211
  39. Doolittle, Nancy D.; Peereboom, David; M. Christoforidis, Gregory A.; Hall, Walter A.; Pamieri, Diane; Brock, Penelope R.; Campbell, Kathleen C.M.; Dickey, D. Thomas; Muldoon, Leslie L, O’Neill, Brian P; Peterson, Darryl R.; Pollock, Brad; Smith, Quentin; Sousain, Carole; Tyson, Rose Marie; Neuwelt, Edward “Delivery of Chemotherapy and Antibodies Across the Blood Brain Barrier and the Role of Chemoprotection, in Primary and Metastatic Brain Tumors: Report of the Eleventh Annual Blood-Brain Barrier Consortium Meeting. Journal of Neuro-Oncology (2007) Journal of Neurooncology Jan;81(1):81-91 (e-pub Jul 21, 2006)
  40. Campbell, Kathleen C.M., Meech, Robert P.,Klemens, James J., Gerberi, Michael. T.,Dyrstad Sara S.W.,Larsen Deb. L,Mitchell, Diana L., ^El-Azizi, Mohammed, Verhulst, Steven J., Hughes, Larry F “Prevention of Noise- and Drug-Induced Hearing Loss with D-methionine” Hearing Research (2007) Apr; 226(1-2):92-103 (e-pub Jan 16, 2007)
  41. Vuyyuri, S.B., Hamstra, D.A., Khanna, D., Hamilton C.A., Marwart SM, Campbell K.C.M., Sunkara, P, Ross, B.D, and Rehemtulla, A.**(2008)*“*Evaluation of a D-Methionine as a Novel Oral Radiation Protector for Prevention of Mucositis” Clinical Cancer Research (2008) April 1;14(7): 2161-70
  42. Durrant, J. Campbell. K., Fausti, S. Guthrie, O., Jacobson, G., Lonsbury-Martin, B.. and Poling, G. American Academy of Audiology Position Statement and Clinical Practice Guidelines October 2009, Audiology.org pgs. 1-25
  43. Daniel Hamstra, Avraham Eisbruch, Maddireddy Naidu, Gogula Ramana, Prasad Sunkara, Kathleen Campbell, Brian Ross, Alnawaz Rehemtulla. Pharmacokinetic Analysis and Phase 1 Study of MRX-1024 in Patients Treated with Radiation Therapy with or without Cisplatinum for Head and NeckCancer. Clinical Cancer Research 2010 May 1:16(9):266-76 Epub April 13, 2010
  44. Le Prell, C. G., Hensley BN, Campbell, K. C, Hall, J. W. 3^rd and Guire, K. Hearing outcomes in a “normally-hearing” college-student population: Evidence of hearing loss Int J Audiol. 2011 Mar;50 Suppl 1:S21-31
  45. Campbell, Kathleen, LePrell, Colleen “Potential Therapeutic Agents” Seminars in Hearing. 2012: Vol. 33L1_ epub ahead of print
  46. Lorito G, Hatzopoulos S, Laurell G, Campbell KC, Petruccelli J, Giordano P, Kochanek K, Sliwa L, Martini A, Skarzynski H.”Dose-dependent protection on cisplatin-induced ototoxicity - an electrophysiological study on the effect of three antioxidants in the Sprague-Dawley rat animal model. Med Sci Monit. 2011 Aug 1;17(8):BR179-186.
  47. Campbell, Kathleen “Ototoxicity Monitoring” Seminars in Hearing. Vol 32:2, 196-202, 2011
  48. Campbell, Kathleen; Claussen, Alex;Meech, Robert, Verhulst, Steven; Fox, Daniel; Hughes, Larry “D-Methionine (D-met) Significantly Rescues Noise Induced Hearing Loss: Timing Studies” Hearing Research (Web release September, 2011)Volume 282, Issues 1-2 December 2011, Pages 138-144
  49. Le Prell C, Johnson, A., Skjonsberg A., Ulfendahl M., Guire K. Green G., Campbell K. Miller J. “Dietary nutrients and protection against noise insult: A first translation from bench to bedside” In press. Noise and Health
  50. Penelope Brock, *Kristin Knight, David Freyer, Kathleen Campbell, Peter S. Steyger, Brian W. Blakley, S. Rod Rassekh, Kay W. Chang, Brian Fligor, Michael Sullivan, Edward A. Neuwelt “Platinum-induced ototoxicity in children: a consensus review on ototoxicity, otoprotection and monitoring” In press Journal of Clinical Oncology (JCO)
  51. Le Prell, C.G., Johnson, A.-C., Lindblad, A.-C., Ulfendahl, M., Campbell, K.C.M., Kujawa, S.G., Green, G.E., Miller, J.M., Guire, K. 2011. Increased vitamin plasma levels in Swedish military personnel treated with nutrients prior to automatic weapon training Noise Health, 13:55 pp 432-43
  52. Gopal, KV; Wu C. Shreshta, B. Campbell, KCM; Moore EJ, Gross, GW D-Methionine Protectsagainst Cisplatin-induced Neurotoxicity in Cortical Networks Submitted for Publication


 
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