SIU Division of Orthopaedic Surgery 
Phone: 217-545-8000
Fax: 217-545-2536
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Clinical Research

Clinical & Translational

Under the guidance of Dr. Khaled J Saleh, both clinical and translational research occurs at SIU SOM.
Clinical research is patient-oriented research, in which the researcher interacts with human subjects directly. At SIU SOM, the main type of clinical research is completed through clinical trials. Although there are many definitions of clinical trials, they are generally considered to be biomedical or health-related research studies in human beings that follow a pre-defined protocol. includes both interventional and observational types of studies. Interventional studies are those in which the research subjects are assigned by the investigator to a treatment or other intervention, and their outcomes are measured.  Observational studies are those in which individuals are observed and their outcomes are measured by the investigators.


Translational research is patient-oriented research that encourages and embraces technological and biomedical innovation. As such, translational research incorporates two areas of research: apply the findings from the lab to clinical practice AND from clinical practice to the community.
For examples of SIU SOM clinical and translational research, click on the links below.
Research Accomplishments