- Health Policy and health Care Reform
- Cost-Benefit Analysis/Cost-Effectiveness Analysis/Cost Utility Analysis
- Evidence Based Practices/Guidelines Development
- Public Health and Patient Safety Projects
- Clinical Operations Improvement Projects
- Health Technology Assessment
- Multi-Center Clinical Trials
Research studies
- Lead and Develop Innovative and Measurable Programs Aimed at Improving Patient Safety, Quality of Care, and Health Outcomes
- Develop Initiatives with Specific Emphasis on Process Redesign, Clinical Transformation and the Development of Evidenced Based Clinical Protocols
- Leverage Clinical Information Systems to Help Guide Clinical Process Redesign, Compliance with Core Measures and Other Quality Indicators as well as Public Reporting Requirements
- Forming A State-Wide Joint Replacement Registry
- Multi-Center Study Predicting Outcomes Following Knee Replacement
- Multi-Center Study Predicting Outcomes Following Knee Revision Surgery Replacement
- Validating A New Lower Extremity Activity Scales
- Biomechanics of Knee Replacement
- Avascular Necrosis Biologic Interventions
- Using EMR to Track Implants
- Assessing Pain Ratings as a Predictor of Patient Satisfaction Following Surgery
- Managing and Optimizing Operating Room Efficiency
- Patient Safety Implementing a Cultural Change in Academic Medical Centers
- Creating Center of Excellence in orthopaedics: The 6 Ws
Clinical trial participation
Knee Arthroplasty Cognitive Behavioral
Intervention: The (KABIC) Trial 07/09-6/2010 $190,350
Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases
Role: Co-Investigator (PI: D. Riddle, Ph.D.)
Goal: To compare cognitive behavioral therapy (CBT) to an educational control intervention in patients undergoing knee arthroplasty, mostly with the goal of decreasing longer-term post-operative pain, up to 1 year after the surgery.
Salary Support: 3% effort
NIH Evidence Technology Total
Knee Replacement 06/02-12/03 $232,649
Sponsor: Agency Healthcare Research and Quality (in conjunction with OMAR & NIAMS)
Role: Co-Investigator (PI: R Kane)
Goal: Assess and summarize the literature pertaining to total knee replacement consensus support and technical report preparation. Expert panelist on revision knee surgery.
Salary Support: 10% Effort.
Multi-Center Clinical Trial of the Application
of Tissue Repair Cell (TRC) Therapy of
Osteonecrosis of the Femoral Head 9/07-8/08 $138,831.25
Sponsor: Aastrom Biosciences
Role: Co-Principal Investigator
Goal: To measure the efficacy and effectiveness of using autologous bone marrow-derived stem and progenitor cells for the treatment of osteonecrosis of the femur head.
Salary Support: 0% Effort.
Aesculap Outcomes Research 11/07-10/08 $90,000
Sponsor: B. Braun-Aesculap
Role: Principal Investigator
Goal: Systematic review and meta-analysis on the value of navigation in joint replacement surgery; protocol design for multi-center trial on the value of navigation in joint replacement surgery; analysis of experimental studies concerning allergic reactions to implant materials; analysis of experimental results of biomechanical considerations in modular component connections in revision total knee arthroplasty
Salary Support: 5% Effort
Triathlon Multicenter Outcomes Study 09/05-12/08 $690,625
Sponsor: Stryker orthopaedics
Role: Principal Investigator
Goal: Randomized ten-center study 1) assessing radiographic wear rates and osteolysis, 2) assessing predictors of radiographic osteolysis and TKA failure in a cohort of 600 TKA in a consecutive series of PCL retaining vs. substituting, and 3) Quality of life outcomes and several musculoskeletal instruments that we developed are being validated.
Salary Support: 20% Effort.
Biomaterial-Centered Infection Research
Laboratory 12/04-04/06 $181,877
Sponsor: NABI
Role: Co-Investigator (PI: T. Brown)
Goal: Assess Staph Epidermis Vaccine against antibiotic in the treatment of biomaterial-centered infections in the rabbit model
Salary Support: 0% Effort.
Effectiveness of Revision Knee Surgery 06/00-01/06 $225,000
Sponsor: Orthopaedic Research Education Foundation.
Role: Principal Investigator
Goal: a) To undertake a TKA. Revision meta-analysis. 2) Undertake a prospective Thirteen-center cohort study, assessing predictors of outcomes following revision knee surgery.
Salary Support: 10% Effort. (No support to UVA)
Oxinium Head (SNOH) 06/02-06/05 $1,489,000
Sponsor: Smith & Nephew Inc.
Role: Principal Investigator
Goal: Randomized ten-center study 1) assessing radiographic wear rates and osteolysis, 2) assessing predictors of radiographic osteolysis and THA failure in a cohort of 1000 THA randomized to two bearing surfaces, and 3) quality of life outcomes and several musculoskeletal instruments that we developed are being validated.
Salary Support: 5% Effort. (No support to UVA)
Predictors of Outcome Following Revision
Knee Surgery 06/02-06/04 $150,000
Sponsor: American Geriatrics Society
Role: Principal Investigator
Goal: Prospective seventeen-center cohort study assessing predictors of outcome following revision knee surgery.
Salary Support: 50% Effort.
Severity Index For Total Hip Revision
Arthroplasty: Development and Validation 08/98-06/00 $135,000
Sponsor: Medical Research Council of Canada
Role: Principal Investigator
Goal: To develop and validate severity index instrument to stratify patients in need of THA based on predicted outcome.
Salary Support: 50% Effort.
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