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In addition to their teaching and clinical responsibilities, faculty members of the Department of Surgery engage in research activities. In terms of dollars, the Southern Illinois University School of Medicine Department of Surgery is ranked No. 1 compared to community-based medical schools for research grant income. Overall, as of 1999, the department is ranked No. 66 out of surgery departments receiving NIH funding.
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| Location
of lab: |
Microsurgery
lab 3rd floor 801 Bldg |
| Area
of research: |
Tissue Engineering:
cartilage, bone, nerve, fat,skin
Ischemia Reperfusion
Flap Physiology
Angiogenesis
Synthetic Antimicrobial peptides in burns and cancer |
| Techniques
used: |
gene array
RT-PCR |
| Clinical
trials: |
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| Collaboration: |
Bill Whitson,
DDS, Edwardsville,IL. Shelly Wynn, Washington, OR |
| Funding
sources: |
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| Researchers
in lab: |
Christopher Chambers,
PhD, Hans Suchy MS, Jagedish Hegde MBBS, MS |
| Manuscripts: |
For a complete view
of Dr.Neumeister's manuscripts click
here. |
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| Location
of lab: |
Microsurgery
lab 3rd floor 801 Bldg |
| Area
of research: |
Outcome studies
in Fingernails, fingertips and Breast surgery |
| Techniques
used: |
Outcome studies |
| Clinical
trials: |
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| Collaboration: |
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| Funding
sources: |
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| Researchers
in lab: |
Christopher Chambers,
PhD, Hans Suchy MS, Jagedish Hegde MBBS, MS |
| Manuscripts: |
For a complete view
of Dr.Zook's manuscripts click
here. |
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| Location
of lab: |
Microsurgery
lab 3rd floor 801 Bldg |
| Area
of research: |
Outcome studies
in Aesthetics and Breast surgery
Flap physiology |
| Techniques
used: |
Outcome studies,
Gene transfection |
| Clinical
trials: |
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| Collaboration: |
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| Funding
sources: |
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| Researchers
in lab: |
Christopher Chambers,
PhD, Hans Suchy MS, Jagedish Hegde MBBS, MS |
| Manuscripts: |
For a complete view
of Dr. Sommer's manuscripts click
here. |
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| Location
of lab: |
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| Area
of research: |
Conflict in Medical
Learning Groups |
| Techniques
used: |
Surveys, focus
groups, direct observation |
| Clinical
trials: |
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| Collaboration: |
Dr. Lorele Lingard
- University of Toronto
Dr. Debra Darosa - Northwestern University |
| Funding
sources: |
C SERT, CO-PI |
| Researchers
in lab: |
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| Manuscripts: |
For a complete view
of Dr.Roger's manuscripts click
here. |
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| Location of lab: |
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| Area of research: |
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| Techniques used: |
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| Clinical trials: |
Epogen-ICU |
| Collaboration: |
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| Funding sources: |
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| Researchers in lab: |
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| Manuscripts: |
For a complete view of Dr.Wohltmann's manuscripts click here. |
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| Location
of lab: |
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| Area
of research: |
Clinical studies
with patient availability in trauma and morbid
obesity. |
| Techniques
used: |
Erythropoiten
in critical care |
| Clinical
trials: |
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| Collaboration: |
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| Funding
sources: |
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| Researchers
in lab: |
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| Manuscripts: |
For a complete view
of Dr.Sutyak's manuscripts click
here. |
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| Location
of lab: |
801
N. Rutledge |
| Area
of research: |
Mammary carcinogenesis
and breast cancer prevention
Angiogenesis in metastatic melanoma and breast carcinoma |
| Techniques
used: |
Immunohistochemical
assessment of angiogenesis
Cellular proliferation and apoptosis assays
Assay of adipocyte differentiation and aromatase expression |
| Clinical
trials: |
Surrogate Endpoint
Biomarkers in the Nutritional Prevention of
Breast Cancer
Interaction of Vitamin E with Tamoxifen in the Adjuvant
Treatment
of Breast Cancer |
| Collaboration: |
Sophia Ran, Ph.D.
Medical Microbiology and Immunology
Yuqing Hou, Ph.D., Chemistry and Biochemistry (Carbondale) |
| Funding
sources: |
CRC |
| Researchers
in lab: |
Deborah Engle,
M.S. |
| Manuscripts: |
For a complete view
of Dr. Peralta's manuscripts, click
here. |
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| Location
of lab: |
Rm. 3205, 801
North Rutledge |
| Area
of research: |
Tinnitus |
| Techniques
used: |
Cochlear histology,
microdissection, phase contrast microscopy,
transmission electron microscopy; round window application
of
ototoxins; acoustic trauma; electrophysiology of central
auditory
system, multiunit electrode recording. |
| Clinical
trials: |
The effect of
gabapentin on the sensation and impact of tinnitus,
2003-2005. |
| Collaboration: |
Dr. Thomas J.
Brozoski, Dr. Donald Caspary, Dr. Jeremy Turner |
| Funding
sources: |
NIDCD, Tinnitus
Research Consortium, AMGEN. |
| Researchers
in lab: |
Christy Johnston, Kristen Rosendale |
| Manuscripts: |
For a complete view
fo Dr. Bauer's manuscripts, click
here. |
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| Location
of lab: |
Within
microvascular lab--3rd floor of 801 bldg |
| Area
of research: |
laryngeal paralysis
& reinnervation |
| Techniques
used: |
EMG. air pressure
& flow recording, endoscopic video
Retrograde brainstem labelling with flourescent tracers
Histology & immunohistochemistry of nerve &
muscle |
| Clinical
trials: |
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| Collaboration: |
Bob Helfert, PhD |
| Funding
sources: |
Departmental |
| Researchers
in lab: |
Myself, &
research associate, Shiloh McFarlin |
| Manuscripts: |
For a complete view
of Dr.Woodson's manuscripts click
here. |
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| Location
of lab: |
801
N. Rutledge; Rm 3205 |
| Area
of research: |
Tinnitus: Animal
models, psychophysical features, central and
peripheral mechanisms. |
| Techniques
used: |
Operant conditioning;
single-unit electrophysiology;
psychophysical methods; evoked-potential recording;
light
microscopy; digital image analysis. |
| Clinical
trials: |
Clinical efficacy
of gabapentin as a treatment for noise-induced and age-associated
tinnitus. |
| Collaboration: |
Donald Caspary,
Ph.D.; Jeremy Turner, Ph.D., Pharmacology |
| Funding
sources: |
National Institute
on Deafness and Communicative Disorders,
DC04830-01A1, 2002-2006.
Tinnitus Research Consortium, 2003-2005. |
| Researchers
in lab: |
Carol A. Bauer,
M.D.; Christy Y. Johnston, B.S.; Kristin
Rosendale, B.S.; Lindsey Kublick, B.S. |
| Manuscripts: |
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| Location
of lab: |
801
N. Rutledge, Fourth Floor |
| Area
of research: |
Mechanisms of
ototoxicity of cisplatin, including cell death pathways
Prevention of cisplatin ototoxicity
Prevention of noise-induced hearing loss
Migration of cells in the lateral wall of the cochlea;
cell transplantation in the cochlea |
| Techniques
used: |
Auditory brainstem
evoked potentials
Scanning electron microscopy
Cell culture of cochlear hair cells
Fluorescent immunolabeling of adenosine receptors
RT-PCR for adenosine receptors, subunits of NADPH oxidase,
flow cytometry, cell culture |
| Clinical
trials: |
None currently |
| Collaboration: |
Vickram Ramkumar,
George Dunaway (both in pharmacology) Bob
Helfert, Kathleen CAmpbell (otolaryngology), Larry Hughes,
Bob
Struble (psychiatry) |
| Funding
sources: |
NIH (NIDCD) |
| Researchers
in lab: |
Craig Whitworth,
M.A. |
| Manuscripts: |
For a complete view
of Dr. Rybak's manuscripts click
here. |
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| Location
of lab: |
801 N. Rutledge,
Rm 3234 |
| Area
of research: |
Bench to bedside research in development of protective agents:
Prevention of radiation-induced oral mucositis
Prevention of cisplatin-induced hearing loss, nephropathy, alopecia, and neurotoxicity
Prevention of aminoglycoside-induced hearing loss and nephrotoxicity
Prevention of noise-induced hearing loss
Studies include bench work through clinical trials.
All patents licensed by Molecular Therapeutics.
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| Techniques
used: |
Auditory brainstem evoked potentials
Scanning electron microscopy
HPLC
Spectrophotometry
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| Clinical
trials: |
Several in progress for various areas listed above. |
| Collaboration: |
Leonard Rybak, MD, PhD Larry Hughes,PhD, Joe Miller, PhD
Colleen LePrell, PhD |
| Funding
sources: |
NIH (NIDCD) |
| Researchers
in lab: |
Robert Meech, MA |
| Manuscripts: |
For a complete view of Dr. Campbell’s manuscripts click here. |
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| Location
of lab: |
801 N. Rutledge,
Rm 3234 |
| Area
of research: |
Pharmacology and
plasticity of the central auditory pathway.
Neurotransmitters of the Auditory Pathway.
Aging and Tinnitus of the Central Auditry Pathway |
| Techniques
used: |
Electrophysiology and Molecular neurochemistry. |
| Clinical
trials: |
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| Collaboration: |
L.Hughes, C. Bauer,
Tom Brozoski, R Helfert, J. Turner. |
| Funding
sources: |
NIH RO00151-24 |
| Researchers
in lab: |
J. Turner, L .Hughes, L Ling, J Parrish |
| Manuscripts: |
For a complete view
of Donald Caspary's manuscripts, click here. |
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| Location of lab: |
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| Area of research: |
Stone disease, nanotechnology, miniaturization of instrumentation, laparoscopy,
robotic surgery, biomedical devices |
| Techniques used: |
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| Clinical trials: |
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| Collaboration: |
Established the biomedical initiative with SIU Carbondale.
Have done projects with Clipius Technologies Inc,
Tyco Healthcare and Malinckrodt radiologic. |
| Funding sources: |
Pharmaceutical companies, device companies,
SIU. |
| Researchers in lab: |
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| Manuscripts: |
For a complete view of Dr.Schwartz's manuscripts click here. |
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| Location
of lab: |
913
Rutledge |
| Area
of research: |
Suppression of
Anti-tumor Immunity by Renal Cell Carcinoma |
| Techniques
used: |
ELISA |
| Clinical
trials: |
1. REDUCE Trial:
Dutasteride Prostate Cancer Prevention Trial
(GlaxoSmithKline)
2. SPIRIT Trial: Randomized Trial of Radical Prostatectomy
v.
Radiation Therapy for Men with Low Risk Prostate Cancer
(American
College of Surgeons)
3. Computer Assisted Pelvic Floor Training in Men Treated
for
Prostate Cancer (St. John's Foundation) |
| Collaboration: |
Sophia Ran, Ph.D |
| Funding
sources: |
Department of
Surgery |
| Researchers
in lab: |
Thomas H. Tarter,
M.D., Ph.D. |
| Manuscripts: |
For a complete view
of Dr.Tarter's manuscripts click
here. |
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| Location of lab: |
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| Area of research: |
Joint replacement |
| Techniques used: |
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| Clinical trials: |
Vioxx post-operative pain study in knee arthroscopy patients
UNI knee replacement
NEX GEN knee replacements
Versys hip replacements |
| Collaboration: |
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| Funding sources: |
Merck |
| Researchers in lab: |
Candi Bearss |
| Manuscripts: |
For a complete view of Dr.Olysav's manuscripts click here. |
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| Location of lab: |
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| Area of research: |
Area of research focuses primarily on the pathophysiology, diagnosis and management of diabetes related foot and ankle complications (neuropathy, infections, neuropathic ulcers and Charcot (arthropathy). Our research also addresses ways to reduce these complications and, ultimately, decrease the incidence of diabetes-related lower extremity amputations. |
| Techniques used: |
Computer Aided Design and Modeling; Finite Element Analysis, Mechanical Testings, Material Characterization using SEM, Light Microscopy, XRD; Data acquisition using transducers; Digital signal processing using MATLAB." |
| Clinical trials: |
1. Prevalence of foot and ankle pathology and lower extremity complications in a diabetic outpatient clinic.
2. The epidemiology of lower extremity amputations in diabetic individuals. |
| Collaboration: |
A. Collaboration with Dr. Geza Kogler on:
1. "Tensile Loading of The Plantar Aponeurosis During Dynamic Simulations of the Windlass Action of the Foot."
2. "The Effect of Partial Plantar Fasciotomy on the Loading Characteristics of the Plantar Aponeurosis in Vivo."
B. Collaboration with Jayson Coble, MS, PA, on diabetic foot clinical trials. |
| Funding sources: |
Randomized controlled trial of a specific form of demineralized bone matrix (Grafton demineralized bone matrix putty) versus autologous bone grafting in orthopaedic procedures. $10,000.00 |
| Researchers in lab: |
Orthopaedic Bioengineering Laboratory: Manish Paliwal, PhD.; Geza Kogler, PhD.; Rita Trammell, Phd.; Osaretin Idusuyi, MD; Gorden Allan, MD |
| Manuscripts: |
For a complete view of Dr.Idusuyi's manuscripts click here. |
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| Location
of lab: |
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| Area
of research: |
Lung cancer prevention, diagnosis, and
treatment. Coronary
revascularization techniques and prevention of postoperative
complications. Stem cell treatment for cardiac failure. |
| Techniques
used: |
Basic science research allows laser
revascularization,
cardiopulmonary bypass, echocardiography, cine viewing |
| Clinical
trials: |
Intraoperative I-125 Brachytherapy Following
Sublobar Resection in
High Risk Patients with Stage I Non-Small Cell Lung
Carcinoma
A Phase III Prospective Randomized, Double-Blind, Placebo-Controlled
Trial of the Epidermal Growth Factor Receptor Antagonist,
ZD1839 (IRESSA) in Completely Resected Primary Stage
IB, II
and IIIA Non-Small Cell Lung Cancer.
VENT: Endobronchial Valve for Emphysema Palliation Trial
Prevent IV study: A Phase III, Multi-Center, Randomized,
Double-Blind Placebo Controlled Trial of the Ex Vivo
Treatment with
CGT003 of Coronary Vein Grafts in Patients Undergoing
Coronary Artery
Bypass Graft Procedure
A Comparison of Video-Assisted and Thoractotomy Lobectomy |
| Collaboration: |
Collaboration with Cardiology, Pulmonary
Medicine, Plastic
Surgery, Radiology, Internal Medicine, Oncology. |
| Funding
sources: |
Telehealth Implementation Pilot Projects
Award-1/01-12/02-
$33,719.78
American College of Surgeons Oncology Group-7-6-00-Per
Patient
SIU/CRC-2002-2004-$13,500
McElroy Foundation-2002-2004-$35,200
Duke Clinical Research-9-20-02-Per patient
National Institute of Health NIH)-1/1/03-12/31/04-$100,000
Excellence in Academic Medicine (EAM)-1/1/03-12/31/04-$2,500 |
| Researchers
in lab: |
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| Manuscripts: |
For a complete view
of Dr.Hazelrigg's manuscripts click
here. |
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| Location
of lab: |
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| Area
of research: |
Pain management, lung cancer, coronary
revascularization,
reduction of complications after open heart surgery |
| Techniques
used: |
Basic science research allows Laser
revascularization,
cardiopulmonary bypass, echocardiography cine viewing |
| Clinical
trials: |
Effect of Sternotomy vs Vats on Postoperative
Pain Associated
Complications of Pulmonary Resection
Thoracoscopic Treatment of Diffuse Bullous Emphysema
Z0030 Randomized Trial of Mediastinal Lymph Node Sampling
Versus
Complete Lymphadenectomy During Pulmonary Resection
in the Patient with NO or NI (less than Hilar) Non-Small
Cell Carcinoma
Z0040 A Prospective Study of the Prognostic Significance
of Occult
Metastases in the Patient with Resectable Non-Small
Cell Lung Carcinoma
Value of 6 minute walk as a predictor of Hospital and
Long-Term
Outcome of Lung Volume Reduction Surgery. |
| Collaboration: |
Collaboration
with Cardiology, Pulmonary Medicine, Internal
Medicine, Oncology |
| Funding
sources: |
Telehealth Implementation Pilot Projects
Award-1/01-12/02-
$33,719.78
American College of Surgeons Oncology Group-7-6-00-Per
Patient
SIU/CRC-2002-2004-$13,500
McElroy Foundation-2002-2004-$35,200
Duke Clinical Research-9-20-02-Per patient
National Institute of Health NIH)-1/1/03-12/31/04-$100,000
Excellence in Academic Medicine (EAM)-1/1/03-12/31/04-$2,500 |
| Researchers
in lab: |
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| Manuscripts: |
For a complete view
of Theresa Boley's manuscripts click
here. |
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