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Research Overview

The Surgery Specialties at SIU School of Medicine is dedicated to bringing the latest adavanced treatments and technology to citizens of Illinois and beyond. We have dedicated researchers, faculty and staff conducting basic, clinical, educational, epidemilogical, and translational research. Our dedication to providing quality care to our patients has created a culture of collaboration and teamwork throughout our areas of research. SIU is a member of the Midwest Healthcare Quality Alliance (MHQA). This partnership with Memorial Medical Center is designed to develop innovative solutions for improving healthcare quality, safety, access and community outcomes. Our other partner, St. John's Hospital shares our vision and commitment to patient excellence.

Cardiothoracic Surgery

The Division of Cardiothoracic Surgery has a strong research program that has resulted in greater than 200 publications and presentations. The results from our research efforts influence the care of patients with diseases of the chest. Some of the major areas of research interest of our faculty include lung cancer, valvular heart disease, esophageal disorders, and surgical treatment for emphysema. More information here




Some current trials

Emergency Medicine

There are many opportunities for research involvement during residency training. With faculty interests including medical education, simulation, ultrasound, rural medicine, emergency department utilization, quality improvement, trauma, critical care, and pediatrics to name a few, mentorship in research is more than available. Our core curriculum includes journal clubs, didactics, and small group sessions overviewing hot to write case reports, clinical statistics, and manuscript appraisals. Resources and mentorship from members of the universities Center for Clinical Research are also available to aid in study design, IRB proposals, design implementation, and data analysis. Goals for our residents are for involvement in the production of a manuscript during their tenure with the program as well as abstract presentations at regional and national academic conferences. See below a list of our divisions most recent scholarly activities. more information, click here

Some current publications

  • Pillow, M. T., Hopson, L., Bond, M., Cabrera, D., Patterson, L., Pearson, D., … Takenaka, K. (2013). Social Media Guidelines and Best Practices - Recommendations from the Council of Residency Directors (CORD) Social Media Taskforce. Western Journal of Emergency Medicine. Retrieved from eScholarship
  • Reed, L., Carroll, J., Cummings, A., Markwell, S., Wall, J., & Duong, M. (2013). Serum lactate as a screening tool and predictor of outcome in pediatric patients presenting to the emergency department with suspected infection. Pediatric emergency care, 29(7), 787–91. doi:10.1097/PEC.0b013e318298389d Retrieved from PubMed
  • Cianciolo, A. T., & Kegg, J. A. (2013). Behavioral Specification of the Entrustment Process. Journal of Graduate Medical Education, 5(1), 10–12. doi:10.4300/JGME-D-12-00158.1 Retreived from Journal of Graduate Medical Education




Leonard Rybak, MD, PhDEight laboratories provide state of the art research and research training in Auditory and Vestibular Anatomy, Pharmacology, Physiology of Taste and Smell, Cancer Molecular Biology and Genetics. In alphabetical order these are headed by Carol Bauer, MD; Kathleen Campbell, PhD; Don Caspary, PhD; Jeremy Turner, PhD and Leonard Rybak, MD, PhD Special emphasis is on understanding basic mechanisms and their application to clinical problems such as ototoxicity, aging, Alzheimer's Disease, tinnitus, and cancer. More information here



Some current trials

General Surgery

The Division of General Surgery has a long tradition of nationally and internationally recognized research in the field of surgical education.  Recent projects have focused on team based learning and handoff skills, cognitive task analysis of surgical and endoscopic procedures, surgical skills development, operative performance evaluation, and the identification, classification, and remediation of learning deficiencies.  Projects in development currently include those focused on web based tools and electronic gaming in resident education and resident selection, and studies exploring surgery-specific issues and professionalism.  Members of the division are also involved in international surgical education projects and research, registry based outcomes research, and translational research focused on surgical oncology including breast, colorectal, and pancreatic neoplasia. more

Some Resident Publications

  • Ahad S, Gonczy C, Advani A, Markwell S, Hassan I. “True benefit or selection bias:  an analysis of laparoscopic versus open splenectomy from the ACS-NSQIP”. Surg Endosc Jun 2013;27(1):1865-71.
    PMID:  23355143
  • Advani V, Ahad S, Gonczy C, Markwell S, Hassan I. “Does Resident Involvement Effect Surgical Times and Complication Rates During Laparoscopic Appendectomy for Uncomplicated Appendicitis? An Analysis of 16,849 Cases from the ACS-NSQIP”. Am J Surg. 2012 Mar;2013(3):347-52.
    PMID:  22364902
  • Date DF, Sanfey H, Mellinger J, Dunnington G. “Handoffs in general surgery residency, an observation of intern and senior residents.” Am J Surg 2013 Sep 12 (epub ahead of print).
    PMID:  24035213


Some current trials

  • A-mode Ultrasound Cranial Registration in Neurosurgery - Devin Amin, MD
  • Investigate the Efficacy & Safety of Progesterone in Patients with Severe Traumatic Brain Injury - Jóse Espinosa, MD

Orthopaedic Surgery

Saadiq El-Amin, MDThe conduct of research is critically important to the mission of SIU School of Medicine and the Division of Orthopedics and Rehabilitation.  Research activities within the Division support the delivery of high quality care and provide patients with alternative innovative treatment options. Our faculty have led many research projects and authored a multitude of publications in peer-reviewed journals, ensuring the highest quality care for our patients as well as providing   numerous educational opportunities for students and residents. More information here



Some current trials

  • Evaluation of Tissue Engineered Composites for Bone Regeneration Using Stem Cell Molecular and Gene Analysis- Saadiq El-Amin
  • Molecular Evaluation of Tissue Engineered Matrices--In Vitro and in Vivo Analysis -
    Saadiq El-Amin, MD
  • PMA Postapproval Study for DURALOC Option Ceramic-on Ceramic Hip Prosthesis System -
    Joe Milbrandt, PhD
  • Knee Arthroplasty Pain Coping Training (KAST Pain): A Randomized Trial - Khaled Saleh, MD

Plastic Surgery

Joel Reichensperger, Researcher IIIThe Institute for Plastic Surgery has approximately 2400 square feet of laboratory space in the 801 building of SIU School of Medicine.  1200 square feet are dedicated to rodent microsurgery with 4 operating microsurgery microscopes (Leica Wild 650, Leica M295, Zeiss F125, and Leica Wild M680 equipped with a Sony PDW-10MD video camera with one 31 inch monitor and one 46 inch monitor). More information here




Some current trials

  • Adipose-Derived Mesenchymal Stem Cell Transplantation Potentiates Tissue Reorganization & Repair during Tissue Expansion with Radiotherapy - Nada Berry, MD
  • Microbiologic Comparison of Acellular Dermal Matrices as an Aseptic Reconstructive Material and a Scaffold for Stem Cell In-Growth - Michael Neumeister, MD
  • Application of TRAIL-Expressing ADSCs in Lipofilling - Yang


Urology research labThe division of Urology has the capability, experience, and dedication to research new techniques and technology to aid in the advancement of patient diagnosis,  management, and education across many pathologies in Urology.  Our goal is to become a well-rounded department involved in the full spectrum of research.  We have the ability to participate in the latest industry sponsored clinical drug and device trials for prostate cancer, erectile dysfunction, and BPH to name a few.  All faculty physicians have initiated their own projects with successful funding from NIH, industry, and local grant opportunities.  We also acknowledge the importance of collaboration by forging partnerships with other universities and visiting professors throughout the country. Aside from the clinical research, the division also has two laboratories to conduct basic science experiments.  Not only does our vast involvement in research benefit our patients with state of the art care, but it also allows our medical students and residents to be involved in the forefront of this innovation. More information here


Some current trials

  • CUPPID study: Cardiac & Urologic Pathology/Prevalence Interplay Determination Study -
    Tobias Köhler, MD
  • Prospective Registry of Outcomes with Penile Prosthesis for Erectile Restoration (PROPPER) -
    Tobias Köhler, MD
  • Division of Urology Andrology Fellowship 5-61493-14 71513 McVary SURG ABBVI Div of Urology - Kevin McVary, MD

Vascular Surgery






Some current trials

  • Endologix Suprarenal Bifurcated Powerlink System (Abdominal Aortic Aneurysm Endoluminal Graft Study) - Kim Hodgson, MD
  • Intramuscular Injection of Human Placenta-Derived Cells (PDA-002) w/ Peripheral Arterial Disease & Diabetic Ft - Kim Hodgson, MD
  • Phase 3 Trial of Topical Fibrocaps in Intraoperative Surgical Hemostasis (Finish-3) -
    Kim Hodgson, MD
  • HP802-247 in Treatment of Venous Leg Ulcers >12 cm to <36 cm - Douglas Hood, MD
  • Phase 3 Study Investigating the Safety & Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers - Douglas Hood, MD