SIU Division of Urology 
Phone: 217-545-8000
Fax: 217-545-7305 
Email: urology@siumed.edu  
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Interstitial Cystitis

  • Definition
  • Symptoms

Interstitial cystitis (in-tur-STISH-ul sis-TIE-tis) — also called painful bladder syndrome — is a chronic condition in which you experience bladder pressure, bladder pain and sometimes pelvic pain, ranging from mild discomfort to severe pain.

Your bladder is a hollow, muscular organ that stores urine. The bladder expands until it's full and then signals your brain that it's time to urinate, communicating through the pelvic nerves. This creates the urge to urinate for most people. With interstitial cystitis, these signals get mixed up — you feel the need to urinate more often and with smaller volumes of urine than most people.

Interstitial cystitis most often affects women and can have a long-lasting impact on quality of life. Although there's no treatment that reliably eliminates interstitial cystitis, medications and other therapies may offer relief.

The signs and symptoms of interstitial cystitis vary from person to person. If you have interstitial cystitis, your symptoms may also vary over time, periodically flaring in response to common triggers, such as menstruation, sitting for a long time, stress, exercise and sexual activity.

Interstitial cystitis signs and symptoms include:

  • Pain in your pelvis or between the vagina and anus in women or between the scrotum and anus in men (perineum).
  • Chronic pelvic pain.
  • A persistent, urgent need to urinate.
  • Frequent urination, often of small amounts, throughout the day and night. People with severe interstitial cystitis may urinate as often as 60 times a day.
  • Pain or discomfort while the bladder fills and relief after urinating.
  • Pain during sexual intercourse.

The severity of symptoms caused by interstitial cystitis often varies, and some people may experience periods during which symptoms disappear.

Although signs and symptoms of interstitial cystitis may resemble those of a chronic urinary tract infection, urine cultures are usually free of bacteria. - However, symptoms may worsen if a person with interstitial cystitis gets a urinary tract infection.

Make an appoinment to see an SIU doctor

If you're experiencing chronic bladder pain or urinary urgency and frequency, contact SIU Healthcare.