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Your doctor has recommended an ultrasound guided prostate biopsy based on your PSA results and/or an abnormal prostate exam.


  • One WEEK prior to the test, do not take any aspirin or ibuprofen (Advil or Motrin).
  • If you are taking blood thinners, (example, Coumadin, Heparin, or Plavix) please call the prescribing doctor for instructions on stopping these medication.
  • Purchase two Fleets enemas. These can be found at most pharmacies or grocery stores
  • Eat a light meal for supper, the evening before your test.
  • Take one antibiotic tablet after your evening meal.
  • Give yourself a Fleets enema after your evening meal.
  • If you normally eat breakfast, you may have a small meal on the day of your procedure.
  • Give yourself the second Fleets enema after breakfast.

You may receive additional instructions if you have diabetes or your procedure is scheduled for the afternoon or at the hospital.

What to expect:

  • Your ultrasound and biopsy will be done in the clinic at the Prostate Clinic, unless otherwise instructed.
  • You may want someone to accompany you to the appointment. If you have a long drive home, it is advisable to have someone along.
  • The doctor will use a rectal ultrasound probe to measure the size of your prostate.
  • You will then receive a local anesthetic around the prostate. This is a similar medication used by dentists or for minor skin repairs.
  • You may still experience some discomfort from the probe placement but the biopsies are well-tolerated.

Aftercare information:

  • You may drive home, but limit your activities for remainder of the day.
  • Drink plenty of fluids, this will help prevent blood clots and the possibility of a urine infection after the biopsy.
  • You may take Tylenol, or other non-aspirin containing medication for discomfort. Avoid taking aspirin for 24 hours after procedure.
  • Take the second antibiotic tablet the evening of your procedure.
  • Take the last antibiotic the following evening.
  • Urine, stool, and semen may have traces of blood for up to two weeks. This can be intermittent and can be affected by level of daily activity and bowel movements.
  • May resume sexual activities after 24 hours but do not be alarmed if there is blood present in the semen.

    You will need to contact our office immediately or speak to the physician on call for:
  • Fever over 101 degrees
  • If you are unable to urinate
  • Continued bleeding from your penis or rectum that has clots

Awaiting the Results

We will notify you of the biopsy results as soon as they are available.

It can take 3 to 7 working days for the final pathology report to be completed.

Your pathology report will usually show one of three results:
· Benign prostate tissue
· Abnormal cells, known as Prostatic Intraepithelial Neoplasia (P.I.N.)
· Malignant cancer cells

If a follow-up appointment is needed, it will be arranged when you are notified of the test results. Your return visit will be based on the pathology results.

We can be reached at
217-545-7422 or 217-545-7500
After hours: 217-545-8000

The faculty and staff of the Urology Division at SIU School of Medicine are excited about the latest developments in the Division of Urology in the Department of Surgery. The Division of Urology has seen tremendous expansion over recent years. Qualified physicians that specialize in several areas of urology treatment and research have come to the Springfield area. Areas of specialization include Pediatric Urology, Endoscopic Urology, Oncologic Urology, Female Incontinence, and Kidney Stone Disease Mangement.

In addition to our specialized areas, the Urology Division is expanding its role in resident education and medical student education at the university. Our goal is to bring innovative treatment to aptients in central and southern Illinois.

You can download a brochure version of this by clicking here