This image shows connective tissue deep in skin.
Fibrous connective tissue of the dermis occupies most of the area of this image and includes a conspicuous artery, several small veins, a small peripheral nerve, and a cluster of lymphocytes (representing mild perivascular inflammatory infiltrate).
The pink color in this image represents eosinophilic material, in this case mostly one of the following:
- Most of the pink material represents extracellular collagen fibers.
- The somewhat deeper pink encircling the artery represents the cytoplasm of smooth muscle cells.
The pale background color represents unstained material, in this case one of the following:.
- Elsewhere, the thin interconnected pale spaces between collagen fibers represent connective tissue ground substance.
The very dark purple (nearly black) spots are cell nuclei. At this resolution, they cannot be individually identified except by context.
- Nuclei adjacent to the lumen of a blood vessel belong to vascular endothelial cells.
- Nuclei in the muscular wall of an artery may belong to smooth muscle cells.
- Irregular nuclei scattered at random among collagen fibers belong mostly to fibroblasts. Some may also belong to macrophages, mast cells, or capillary endothelial cells.
Bright red within the artery represents many red blood cells.
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SIUC / School
of Medicine / Anatomy / David
Last updated: 23 October 2002 / dgk