Skin Biopsy Specimen
Point and click for more information on a feature.
Features which can be seen in this image include:
- Connective tissue of dermis, with fibers and ground substance.
- Blood vessels.
- The thin endothelial lining of blood vessels contrasts with the cuboidal lining of sweat glands.
- The individual identities of these vessels as venule, arteriole, or capillary are difficult to determine from this image. Arterioles may often be identified by a thin band of smooth muscle encircling the vessel.
- The blood vessels are associated with mild perivascular inflammatory infiltrate.
- "Perivascular" simply means "around the blood vessels". "Inflammatory infiltrate" consists of white blood cells which enter the tissue as part of the inflammatory response.
- Although it is not practical to identify reliably most individual cells in this region, the numerous small, roundish, intensely basophilic nuclei seen in this region are characteristic of lymphocytes.
- The inflammatory infiltrate is characterized as "mild" based on the relatively low numbers of white blood cells which appear here. This appearance should be contrasted with a more severe inflammatory infiltrate observable in other slides of inflamed tissue.
- A few small nerves (or a few sections or branches of one nerve).
- Nerves near the surface of the skin are generally small and inconspicuous, although deeper -- where more axons are bundled together -- they can be more noticable and easier to recognize.
- A somewhat larger nerve may be seen by clicking here. But you'll need to click on "Back" to return to this page.
- Many small features (such as individual fibroblasts and collagen fibers) are not individually labelled.
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SIUC / School
of Medicine / Anatomy / David
Last updated: 11 December 2007 / dgk