MBMB 451b

Copyright 2000, E.C. Niederhoffer

Sample Problem

A cartoon representation of the active sites and the reactions catalyzed by lactate dehydrogenase (LDH) and glyceraldehyde-3-phosphate dehydrogenase (G3PDH) are shown below. Briefly point out a possible role for His195 in LDH and Cys149 in G3PDH in the mechanism of action of these enzymes.




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