Mid-Unit Topics

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I anticipate the following topics will be assessed on the mid-unit examination based upon the posted consensus learning issues:

Mid-unit topics
 Topic  Description  ePBLM

Acetylcholine synthesis and receptor

biosynthetic pathway of acetylcholine, importance of enzymes and coenzymes, acetylcholine receptor properties

James, Anderson, Souders, Franks, Huff

Dystrophin - connection to extracellular matrix

dystrophin and sarcolemma complexes and interactions, detection methods, clinical markers

Anderson
general pathways and gross regulation of energy production in muscle and nervous tissue, role of calcium, vitamins and nutrition
Anderson, Huff

Prostaglandins, thromboxanes, and leukotrienes - aspirin/steroids

biosynthetic pathway to prostaglandins, leukotrienes, and thromboxanes, effects of NSAIDs (aspirin) and steroids, comparison of COX enzymes

James, Anderson, Souders, Franks, Huff

Signal transduction of gustation, olfaction, phototransduction

molecular features and comparison of taste, smell, and vision pathways

Franks, Vision mc

Vitamins

role of vitamins on general metabolic pathways and neurotransmitter synthesis (acetylcholine and glutamate)

James, Anderson, Souders, Franks, Huff, Vision mc

I suggest, as I have done so previously in the help sessions, that you would do well to be familiar with the content and concepts that appear on the PowerPoint animations that are available on this web site. My help sessions focused on these topics, which were the consensus learning issues. Self-assessment questions and answers (SAQs) have been available for your practice.

If you need additional resources, please contact me and I encourage you to read each case's correlated readings in Devlin (Devlin, T. M. (ed.). 2002. Textbook of biochemistry with clinical correlations, 5th ed. John Wiley & Sons, Inc., New York) or appropriate material in Nelson and Cox (Nelson, D. L., and M. M. Cox. (ed.). 2000. Lehninger principles of biochemistry, 3rd ed. Worth, New York).

 

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