Mid-Unit Topics

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I anticipate the following topics will be assessed on the mid-unit examination based upon the posted consensus learning issues:

Mid-unit topics

 Topic  Description  ePBLM

Acetylcholine synthesis and receptor

biosynthetic pathway of acetylcholine, importance of enzymes and coenzymes, acetylcholine receptor properties

Souders, James, Salasoo, Franks

Dystrophin - connection to extracellular matrix

dystrophin and sarcolemma complexes and interactions, detection methods, clinical markers

Salasoo
biosynthetic pathway to prostaglandins, leukotrienes, and thromboxanes, effects of NSAIDs (aspirin) and steroids, comparison of COX enzymes
Souders, James, Salasoo, Franks
general pathways and gross regulation of energy production in muscle tissue, role of calcium, vitamins and nutrition
James, Salasoo

Signal transduction of gustation, olfaction, phototransduction

molecular features and comparison of taste, smell, and vision pathways

Franks, Vision mc

I suggest, as I have done so previously in the resource sessions, that you would do well to be familiar with the content and concepts that appear on the biochemistry animations that are available on this web site and Blackboard and from Drs. Davie and Weilbaecher presentations; all of these have been posted on Blackboard. These resource sessions focused on these topics, which were the final learning issues. Self-assessment questions and answers (SAQs) have been available for your practice.

If you need additional resources, please contact me and I encourage you to read each case's correlated readings in Devlin (Devlin, T. M. (ed.). 2010. Textbook of biochemistry with clinical correlations, 7th ed. John Wiley & Sons, Inc., New York) or appropriate material in Nelson and Cox (Nelson, D. L., and M. M. Cox. (ed.). 2008. Lehninger principles of biochemistry, 5th ed. Worth, New York).

 

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