Problem Unit #4
Lecture #3
You can click on the link to listen to a RealAudio file of
the day's lecture. The following description contains the material
discussed and the source of the overheads used during the presentation.
- Code:
- D = Devlin (Textbook of Biochemistry with Clinical Correlations)
- ECN = Created by me
- MV = Mathews & van Holde (Biochemistry)
- VV = Voet & Voet (Biochemistry)
Lecture 3 (11/15/99)
49 minutes
- Announcements
- Remember to check the Web site for
updates to the Study Guide
- Lecture #2 review (VV Fig 16.3)
- Glycolysis processes hexoses to trioses
- Investment of 2 ATP, production of
4 ATP, a net of 2 ATP
- Reduction of NAD+ and its
reoxidation using lactate dehydrogenase
- Three key regulatory steps
- Regulatory features of glycolysis
- Overview of regulatory features including
Pasteur effect and H+ (D
Figs 7.13, 7.14, 7.15, 7.17, 7.18)
- Hormone regulation including glucagon,
epinephrine, insulin, bifunctional enzymes and phosphorylation
(D Figs 7.19, 7.21, 7.22, 7.23, 7.24, 7.25a, 7.25b, 7.26,
7.27a, 7.27b, 7.28a, 7.28b, 7.29, 7.30)
- Gluconeogenesis and its regulation
- Starting point for glucose formation
and Cori cycle (D Figs 7.31,
7.32a)
- Pathway summary, by-pass enzymes and
intracellular locations (D Figs 7.33, 7.37)
- Regulatory features (D Fig 7.45)
Remember to look over the Study Guide and textbook sections
for additional illustrations that may assist in your understanding
of the presented material.
PU04
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