News

Alzheimer's researchers note cause of Alzheimer's to be multifaceted in new article

Published Date:

In August 2020, Erin Hascup PhD, Alzheimer's Center Director, and Kevin Hascup PhD, Assistant Professor published "Toward refining Alzheimer's disease into overlapping subgroups."

The topic of the article is to present an alternative hypothesis that AD is the result of multiple interrelated causalities. The intention of this manuscript is to initiate a discussion regarding these multiple causalities and their overlapping similarities.

The idea of creating subgroups allows for better identification of biomarkers across a narrower patient population for improved pharmacotherapeutic opportunities. The interrelatedness of many of these proposed subgroups indicates the complexity of this disorder. However, it also supports that no one single factor may initiate the cascade of events.

Read more at https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/trc2.12070

More from SIU News

Dr. Johnson with cleft patient

The doctors behind the smiles

When a child is born with a cleft lip or palate, SIU Medicine surrounds families with a team devoted to expert care and compassion, from a baby’s first breath to a teen’s final surgery. Our specialists walk alongside families, providing clarity, confidence and lifelong support every step of the way.
Dr. Judy Davie in her lab in Carbondale

From lab to lecture hall, Dr. Judy Davie champions future scientists

Dr. Judy Davie has built a career grounded in discovery, collaboration and mentorship, studying how genes guide muscle development and how cancers disrupt those processes.
Roland and Linda Folse

Generosity as an art form

SIU School of Medicine’s 2025 Distinguished Donors of the Year are a remarkable couple whose unwavering generosity and passion have left a lasting imprint on the school and the region.