Phone Line Dropped Calls

SIU Medicine's primary phone line, 217-545-8000, is experiencing intermittent dropped calls. We apologize for this inconvenience and are working to correct this issue as soon as possible.

News

NIH Grants Boost Research on Depression, Endometriosis Treatments

Published Date:
Two scientists at SIU School of Medicine’s Department of Physiology have received federal funding to develop more effective therapies to treat two major health problems: depression and endometriosis.
 
Depression is a lingering feeling of sadness that interferes with daily life and can last for weeks or months at a time. The National Institutes of Mental Health estimates that 16 million adults – nearly 7 percent of the US population – has at least one major depressive episode annually.
 
Most people, even those with the most severe forms of depression, can get better with treatment. Assistant Professor Xiang Cai, PhD, is studying the fast-acting antidepressant ketamine to better understand how its cellular mechanisms function in the brain. He has received a $682,900 grant from the National Institutes of Health for his research. “Our hope is these laboratory studies can aid the design of a new generation of antidepressants,” said Dr. Cai.
 
More than 5.5 million American women have symptoms of endometriosis, an often painful disorder in which tissue that normally lines the inside of the uterus grows outside of it, on other organs. Endometriosis is estimated to affect approximately 10 percent of reproductive-aged women.
 
Associate Professor Kanako Hayashi, PhD, in collaboration with Dr. J. Ricardo Loret de Mola, professor and chair of the Department of OB-GYN, is conducting experiments that could lead to improved treatments for endometriosis. Hayashi’s research will determine whether an FDA-approved drug (niclosamide) can affect STAT3 gene signaling within cells isolated from the endometrium to reduce inflammation and curb the unwanted growth of nerves and blood vessels, a condition common in endometriosis. An NIH grant of $405,625 will help fund their collaborative, translational studies.
 
Women with endometriosis often have pelvic pain during and between periods, pain during sex, heavy menstrual bleeding and may experience infertility. They often suffer for 6 to 10 years before proper diagnosis. SIU Medicine has multifaceted studies enrolling patients for endometriosis research. If you are interested in participating, please contact Kathleen Groesch at 217-545-6671, or kgroesch@siumed.edu

Schedule an interview or request more information by contacting SIU Medicine's Office of Public Relations and Communications:

Karen Carlson
217.545.3854
 
Lauren Crocks
217.545.3837

More from SIU News

Dawn Defraites & Stcy Grundy

Kenniebrew, McNeese awards celebrate champions of equity, inclusion

During the 2024 Alonzo Kenniebrew Lecture on February 8, Dr. Wendi El-Amin presented awards to honor individuals and a group who continue the challenging work Dr. Kenniebrew modeled, promoting inclusive excellence and equitable practices.
Farm succession series header

SIU Medicine offers virtual series on farm succession planning

Join us for an upcoming live virtual series, "Planning for the Farm's Future and Yours." The FFRI programs are designed to assist farmers and farm families in developing a succession plan for future generations.
Raj @ 3-Minute Thesis

Pharmacology grad student wins SIU 3-Minute Thesis competition

A trio of School of Medicine graduate students put their presentation skills to the test at the Three-Minute Thesis (3MT) competition on the Carbondale campus February 2. They summarized their research in 3 minutes or less using a single PowerPoint slide.