Shanshan Wang, MD, PhD

Instructor
Molecular and Integrative Physiology

    About me

    Gender

    Female

    Education & training

    Medical School
    Zhejiang University School of Medicine, Hangzhou, China (MB; Clinical Medicine)
    Doctorate Degree
    Shanghai Medical College of Fudan University, Shanghai, China (PhD; Treatment and research on coronary heart disease)
    Graduate Degree
    Shanghai University of Traditional Chinese Medicine, Shanghai, China (MS; Integrative Medicine on Cardiovascular Diseases)

    Publications

    1. Wang S, Zheng Z. Differences in Formation of Prepuce and Urethral Groove During Penile Development Between Guinea Pigs and Mice Are Controlled by Differential Expression of Shh, Fgf10 and Fgfr2. Cells. 2025 Feb 27;14(5). doi: 10.3390/cells14050348. PubMed PMID: 40072077; PubMed Central PMCID: PMC11899664.
       
    2. Tan H, Zheng Z, Wang S, Yang L, Widelka M, Chen D. Neonatal exposure to bisphenol analogues disrupts genital development in male mice. Environ Pollut. 2023 Aug 1;330:121783. doi: 10.1016/j.envpol.2023.121783. Epub 2023 May 8. PubMed PMID: 37164221.
       
    3. Tan H, Wu G, Wang S, Lawless J, Sinn A, Chen D, Zheng Z. Prenatal exposure to atrazine induces cryptorchidism and hypospadias in F1 male mouse offspring. Birth Defects Res. 2021 Apr 1;113(6):469-484. doi: 10.1002/bdr2.1865. Epub 2021 Jan 19. PubMed PMID: 33463082; PubMed Central PMCID: PMC7986601.
       
    4. Chang J, Wang S, Zheng Z. Etiology of Hypospadias: A Comparative Review of Genetic Factors and Developmental Processes Between Human and Animal Models. Res Rep Urol. 2020;12:673-686. doi: 10.2147/RRU.S276141. eCollection 2020. Review. PubMed PMID: 33381468; PubMed Central PMCID: PMC7769141.
       
    5. Wang S, Lawless J, Zheng Z. Prenatal low-dose methyltestosterone, but not dihydrotestosterone, treatment induces penile formation in female mice and guinea pigs†. Biol Reprod. 2020 May 26;102(6):1248-1260. doi: 10.1093/biolre/ioaa035. PubMed PMID: 32219310; PubMed Central PMCID: PMC7253790.
       
    6. Wang S, Zheng Z. Differential cell proliferation and cell death during the urethral groove formation in guinea pig model. Pediatr Res. 2019 Oct;86(4):452-459. doi: 10.1038/s41390-018-0236-0. Epub 2018 Nov 22. PubMed PMID: 30467344.
      Wang S, Zheng Z. Insights Figure for "Differential cell proliferation and cell death during the urethral groove formation in guinea pig model". Pediatr Res. 2019 Oct;86(4):546. doi: 10.1038/s41390-019-0462-0. Epub 2019 Jun 18. PubMed PMID: 31212305.
       
    7. Wang S, Shi M, Zhu D, Mathews R, Zheng Z. External Genital Development, Urethra Formation, and Hypospadias Induction in Guinea Pig: A Double Zipper Model for Human Urethral Development. Urology. 2018 Mar;113:179-186. doi: 10.1016/j.urology.2017.11.002. Epub 2017 Nov 16. PubMed PMID: 29155192.
       
    8. Reinartz R, Wang S, Kebir S, Silver DJ, Wieland A, Zheng T, Küpper M, Rauschenbach L, Fimmers R, Shepherd TM, Trageser D, Till A, Schäfer N, Glas M, Hillmer AM, Cichon S, Smith AA, Pietsch T, Liu Y, Reynolds BA, Yachnis A, Pincus DW, Simon M, Brüstle O, Steindler DA, Scheffler B. Functional Subclone Profiling for Prediction of Treatment-Induced Intratumor Population Shifts and Discovery of Rational Drug Combinations in Human Glioblastoma. Clin Cancer Res. 2017 Jan 15;23(2):562-574. doi: 10.1158/1078-0432.CCR-15-2089. Epub 2016 Aug 12. PubMed PMID: 27521447; PubMed Central PMCID: PMC5241221.
       
    9. Zhu D, Wang S, Lawless J, He J, Zheng Z. Dose Dependent Dual Effect of Baicalin and Herb Huang Qin Extract on Angiogenesis. PLoS One. 2016;11(11):e0167125. doi: 10.1371/journal.pone.0167125. eCollection 2016. PubMed PMID: 27902752; PubMed Central PMCID: PMC5130244.
       
    10. Wang S, Okun MS, Suslov O, Zheng T, McFarland NR, Vedam-Mai V, Foote KD, Roper SN, Yachnis AT, Siebzehnrubl FA, Steindler DA. Neurogenic potential of progenitor cells isolated from postmortem human Parkinsonian brains. Brain Res. 2012 Jun 29;1464:61-72. doi: 10.1016/j.brainres.2012.04.039. Epub 2012 Apr 27. PubMed PMID: 22652067; PubMed Central PMCID: PMC3372664.
       
    11. Goetz AK, Scheffler B, Chen HX, Wang S, Suslov O, Xiang H, Brüstle O, Roper SN, Steindler DA. Temporally restricted substrate interactions direct fate and specification of neural precursors derived from embryonic stem cells. Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):11063-8. doi: 10.1073/pnas.0510926103. Epub 2006 Jul 10. PubMed PMID: 16832065; PubMed Central PMCID: PMC1544174.
       
    12. Wang S, Zheng Z, Weng Y, Yu Y, Zhang D, Fan W, Dai R, Hu Z. Angiogenesis and anti-angiogenesis activity of Chinese medicinal herbal extracts. Life Sci. 2004 Apr 2;74(20):2467-78. doi: 10.1016/j.lfs.2003.03.005. PubMed PMID: 15010258.
       
    13. Wang S, Li Y, Fan W, Dai R. Stimulating angiogenesis effect of Shexiang Baoxinwan in CAM and vascular endotheliocytes. Chinese Journal of Integrated Traditional and Western Medicine. 2003; 23(2):128-131.
       
    14. Ruan C, Zhang D, Wang S, Wang J, Fang H. The effect of Astragalus membranaceus on apoptosis of cardiomyocytes after ischemia-reperfusion. Journal of Tongji University(Medical Science). 2003; 3:182-184.
       
    15. Wang S, Li Y, Fan W, Dai R. Stimulating angiogenesis effect of Shexiang Baoxinwan on the hearts of myocardial infarction rats. Chinese Traditional Patent Medicine. 2002; 24(6):446-449.
       
    16. Wang S, He J, Hu W, Fan W. The regulation of Shuang Long Wan on variation of [Ca2+]i made by H2O2. Gansu Journal of Traditional Chinese Medicine. 2002; 15(5):71-74.
       
    17. Wang S, Fan W, Dai R. Angiogenesis and coronary heart disease. In: Dai R, Lin G, Lin G, Lin S, editors. New theory and technology of internal medicine. Shanghai: Shanghai Scientific & Technological Education Publishing House; 2002.
       
    18. Wang S. Participated the translation and editing. In: Liu Z, Zhang D, editors. The Molecular Basis of Cardiovascular Disease: A Companion to Braunwald's Heart Disease. By Kenneth R. Chien, First published in 1999. (Translated Chinese Edition) Shanghai: People's Medical Publishing House; 2002.
       
    19. Wang S, Fan W, Dai R. Angiogenesis and coronary heart disease. Advances in Cardiovascular disease. 2002; 23(2):91-96.