Basic Science Publications

Published work highlighting efforts of the Basic Science Lab

• Daugherty T. Mechanism of Skin Improvement in Radiation Wounds Following Fat Grafting: The Fate of Adipose-derived Stem Cells and Role of Stromal Vascular Fraction. Plastic and reconstructive surgery, Global Open. 2019 August; 7(8s-1):88-89. doi: 10.1097/01.GOX.0000584720.92614.3b.

• Mendenhall SD, Schmucker RW, Daugherty THF, Kottwitz KM, Reichensperger JD, Koirala J, Cederna PS, Neumeister MW. A Microbiological and Ultrastructural Comparison of Aseptic versus Sterile Acellular Dermal Matrix as a Reconstructive Material and a Scaffold for Stem Cell Ingrowth. Plast Reconstr Surg. 2017 Jul;140(1):97-108. doi: 10.1097/PRS.0000000000003448. PubMed PMID: 28654596.

• Lough DM, Chambers C, Germann G, Bueno R, Reichensperger J, Swanson E, Dyer M, Cox L, Harrison C, Neumeister MW. Regulation of ADSC Osteoinductive Potential Using Notch Pathway Inhibition and Gene Rescue: A Potential On/Off Switch for Clinical Applications in Bone Formation and Reconstructive Efforts. Plast Reconstr Surg. 2016 Oct;138(4):642e-52e. doi: 10.1097/PRS.0000000000002551. PubMed PMID: 27673535.

• Lough DM, Wetter N, Madsen C, Reichensperger J, Cosenza N, Cox L, Harrison C, Neumeister MW. Transplantation of an LGR6+ Epithelial Stem Cell-Enriched Scaffold for Repair of Full-Thickness Soft-Tissue Defects: The In Vitro Development of Polarized Hair-Bearing Skin. Plast Reconstr Surg. 2016 Feb;137(2):495-507. doi: 10.1097/01.prs.0000475761.09451.00. PubMed PMID: 26818284.

• Schmucker RW, Mendenhall SD, Reichensperger JD, Yang M, Neumeister MW. Defining the Salvage Time Window for the Use of Ischemic Postconditioning in Skeletal Muscle Ischemia Reperfusion Injury. J Reconstr Microsurg. 2015 Oct;31(8):597-606. doi: 10.1055/s-0035-1556066. Epub 2015 Jul 10. PubMed PMID: 26165885.

• Lough DM, Yang M, Blum A, Reichensperger JD, Cosenza NM, Wetter N, Cox LA, Harrison CE, Neumeister MW. Transplantation of the LGR6+ epithelial stem cell into full-thickness cutaneous wounds results in enhanced healing, nascent hair follicle development, and augmentation of angiogenic analytes. Plast Reconstr Surg. 2014 Mar;133(3):579-90. doi: 10.1097/PRS.0000000000000075. PubMed PMID: 24572851.

• Derby BM, Dai H, Reichensperger J, Cox L, Harrison C, Cosenza N, Yang M, Bueno RA, Neumeister MW. Adipose-derived stem cell to epithelial stem cell transdifferentiation: a mechanism to potentially improve understanding of fat grafting's impact on skin rejuvenation. Aesthet Surg J. 2014 Jan 1;34(1):142-53. doi: 10.1177/1090820X13515700. Epub 2013 Dec 12. PubMed PMID: 24334307.

• Lough DM, Yang M, Blum A, Reichensperger JD, Cosenza NM, Wetter N, Cox LA, Harrison CE, Neumeister MW.  Transplantation of the LGR6+ Epithelial Stem Cell Into Full-Thickness Cutaneous Wounds Results in Enhanced Healing, Nascent Hair Follicle Development, and Augmentation of Angiogenic Analytes.  Plast Reconstr Surg. 2014 MAR;133(3):579-90 DOI:10.1097/PRS. 0000000000000075. PubMed PMID: 24572851.

• Derby BM, Dai H, Reichensperger J, Cox L, Harrison C, Cosenza N, Yang M, Bueno RA, Neumeister MW.  Adipose-Derived Stem Cell to Epithelial Stem Cell Transdifferentiation:  A Mechanism to Potentially Improve Understanding of Fat Grafting’s Impact on Skin Rejuvenation.  Aesthet Surg J. 2014 Jan 1;34(1):142-53. DOI: 10.1177/1090820X13515700. Epub 2013 Dec 12. PubMed PMID: 24334307

• Lough D, Dai H, Yang M, Reichensperger J, Cox L, Harrison C, Neumeister MW. Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Hman Alpha Defensin 5 Results in Deceased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissue Devoid of Adnexal Structures. Plast Reconstr Surg 2013 Nov 132(5):1159-1171.

• Liu G, Neumeister MW, Reichensperger J, Yang RD. Therapeutic potential of human adipose stem cells in a cancer stem cell-like gastric cancer cell model. Int J Oncol 2013 oct;43($): 1301-9. PMID: 23900519

• Derby BM, Reichensperger J, Chambers C, Bueno RA, Suchy H, Neumeister MW. Early Growth Response Factor-1: Expression in a Rabbit Flexor Tendon Scar Model. Plast Reconstr Surg 2012 Mar;129(3):435e-442e. PMID: 22373991

• Roth V, Herron MS, Bueno RA, Chambers CB, Neumeister MW. Stimulating Angiogenesis by Hyperbaric Oxygen in an Isolated Tissue Construct. Undersea Hyperb Med 2011 Nov-Dec 38(6):509-14. PMID: 22292256

• Cooney, DS, Chambers CB, Suchy H, Hornick MC, Reichensperger J, Neumeister MW. Transgene Expression in a Model of Composite Tissue Allotransplantation. Plast Reconstr Surg 2010 Mar: 125(3): 837-845. PMID: 20009792