Institute for Plastic Surgery research projects

SNAPSHOT

Basic science

Heterotopic Ossification: Further Defining Cells of Origin

The goal of the project is to better understand the signaling pathways involved in heterotopic ossification formation and how stem cells contribute to this abnormal bone formation.

Evaluation of Hyperbaric Oxygen Treatment Effects on Peripheral Nerve Regeneration

The goal of this project is to improve outcomes after nerve injuries using hyperbaric oxygen therapy.

Stem Cell Based Vascularized Bone and Cartilage constructs

The goal of the project is to create a stem cell based vascularized bone and cartilage construct to regenerate and repair bone and cartilage deficiencies.

Promoting Burn Wound Healing With Cold Plasma

The goal of this project is to effectively treat burn wounds with cold plasma technology.

Development of a Novel TRAIL Flap for Breast Cancer Treatment  

The goal of this project is to develop a treatment to safely eradicate human breast cancer using a combination of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) gene therapy with a traditional autologous flap technique similar to what is currently used in breast reconstructive surgery.

Competency-Based Microsurgical Education Utilizing Timely Targeted Feedback

The goal of this project is to create effective video education for microsurgery and develop competency-based microsurgical education with timely targeted feedback that can be utilized in surgical programs across the country.

LGR+ Stem Cells Augment Osteogenesis on Bone Defect Scaffolds

The goal of this project is to develop a novel stem cell system utilizing the host’s own stem cells for bone regeneration within fracture defects.

Quality improvement

Quality improvement projects are those that seek to improve a system to improve process efficiency and effectiveness in the hospital and clinic. Examples include developing protocols, order sets, and routines that ultimately result in improvements in patient care.

Memorial Medical Center, one of the community hospitals with which SIU Medicine is affiliated, employs a Lean Six Sigma process to quality improvement projects. All residents receive education regarding the Lean Six Sigma process and receive their “white belt” certification through this program. Residents have the opportunity to pursue a project and further training to earn a Green or Black Belt within this program if they desire. Lean Six Sigma projects are in-depth and allow residents to overhaul systems within the hospital, leading to meaningful change in practice and patient care. Learn more about quality improvement efforts at our partner hospital Memorial Medical Center.

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National recognition. Regional impact. 

“This recognition confirms what we at SIU have always known: that world-class research is happening right here in central and southern Illinois.” – Dr. Jerry Kruse 

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