Kevin Hascup, PhD

Assistant Professor, Smith Alzheimer’s Center

    About me

    Kevin N. Hascup, Assistant Professor in the Department of Neurology at Southern Illinois University School of Medicine, is an experienced neuroscientist with expertise in neurodegenerative disorders, geroscience, neurotransmission, and cognition. He joined Southern Illinois University School of Medicine in 2014 as a Research Associate after completing fellowships at McGill University (2009-2011) and the Karolinska Institute (2008-2009). He received his PhD in Neurobiology from the University of Kentucky (2007) and his BS in Biochemistry from the University of Delaware (2001) and is currently a member of the Alzheimer’s Association and the Society for Neuroscience. In addition to his academic experience, Dr. Hascup has served as the Director of Product Development for BrainBits, LLC (2011-2013) and as a Research and Development Scientist for Dade Behring, Inc (2001-2003).

    Leading a team of scientists at the Dale and Deborah Smith Center for Alzheimer's Research and Treatment, Dr. Hascup’s research focuses on modifiable life-style factors that either increase an individual’s risk for developing Alzheimer’s disease or may be targeted to delay the progression of the disease. The primary emphasis of our laboratory is to understand the alterations among insulin signaling, bioenergetics, glutamatergic neurotransmission, and cognition that occur during disease progression versus successful aging. The long term goal of this research is to define disease-modifying life-style factors concomitantly with biomarker targeted therapeutics that have the potential to improve patient outcome. This novel research has led to extramural funding from the Illinois Department of Public Health as well as the National Institutes of Health.

    Dr. Hascup’s scholarship record includes over 20 peer-reviewed scientific journal articles, 5 book chapters, and more than 50 scientific abstracts. He has been selected to give talks at several national and international society meetings including the Alzheimer’s Association International Conference and the Society for Neuroscience. In addition to his publication record, Dr. Hascup has served as a study section reviewer for the Illinois Department of Public Health and the National Institutes of Health. Dr. Hascup also serves as an Associate Editor for the Journal of Alzheimer’s Disease and an ad hoc reviewer for numerous scientific journals.





    Education & training

    Undergraduate Degree
    Ph.D. University of Kentucky, Lexington, KY
    B.S. University of Delaware, Newark, DE
    Karolinska Institute, Stockholm, Sweden
    McGill University, Montreal, Quebec, Canada
    Southern Illinois University School of Medicine, Springfield, IL

    Academic Location

    Academic Office

    801 N Rutledge St Springfield, IL 62702
    Mail Code: 9628

    Related articles

    Kevin Hascup

    Hascup Lab, SIUC collaboration to explore new path for Alzheimer’s therapy

    A collaboration between neuroscience and engineering will explore a novel approach in reducing formation of plaques commonly found in those with Alzheimer’s. Kevin Hascup, PhD, of the Smith Alzheimer
    Cell sensescence

    Going on the offensive: The potential link between cell senescence and Alzheimer's

    When you catch a cold or cut your finger, the immune system begins the healing process by clearing damaged cells. As we age, that process weakens. Health problems linger as immune systems aren’t quite as robust as they once were, whether it’s fighting bacteria, viruses, or cancer cells. Alzheimer’s researchers are now exploring a process called senescent cell accumulation to see if it could be detrimental.
    Close up of Leica Microscope

    ALS drug shows varying effects against Alzheimer’s, metabolism

    Effects are unique between males and females A recent study from the Hascup labs at SIU Medicine has shown how riluzole, a drug compound typically used to treat amyotrophic lateral sclerosis (ALS)