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By Type

  • (-) Events (207)
  • (-) Trial (47)
  • Condition (1)
  • Departments (100)
  • General Results (2192)
  • Lab (5)
  • Locations (71)
  • Medical Services (12)
  • News (1348)
  • Profiles (1267)
Showing: 254 Results
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Trial
Infectious Diseases

A Phase 2/3, Randomized, Double-blind, Placebo-controlled, Multicenter, Prospective Study to Assess the Efficacy, Safety, and Pharmacokinetics of Orally Administered Epetraborole in Patients with Treatment-refractory Mycobacterium aviu

Active recruiting

The purpose of this clinical trial is to assess the effectiveness of Epetraborole, taken once daily, in patient populations with treatment-refractory MAC lung disease.

Eligible patients include those who currently have a positive MAC sputum culture despite receiving a combination regimen of at least 2 antimycobacterial agents administered for at least 6 months.

Contact: Katherine Martz phone217-545-4342 emailkmartz35@siumed.edu
Trial
Simmons Cancer Institute

A Phase II Open-Label Study of Sacituzumab Govitecan in Unresectable Locally Advanced/Metastatic Urothelial Cancer

Active recruiting

The objective of this study is to evaluate the efficacy and safety of sacituzumab govitecan-hziy monotherapy and with novel combinations in participants with metastatic urothelial cancer (mUC).

Contact: Kathy Robinson phone217-545-1946 emailsciresearchbc@siumed.edu
Trial
Psychiatry

A PRospective, Multi-cEnter, Randomized Controlled Blinded Trial DemOnstrating the Safety and Effectiveness of VNS Therapy® System as AdjunctivE Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression (RECOVER)

Active recruiting

The primary objective of this study is to determine whether active VNS Therapy treatment is superior to a no stimulation control in producing at least a 50% reduction in baseline depressive symptom severity, based on Montgomery Åsberg Depression Rating Scale (MADRS) total score, at 12 months from randomization.

Contact: Oladele (Dickson) Owasoyo phone217-545-7231 emailoowasoyo94@siumed.edu
Trial
Pediatrics

A Randomized, Double Blind, Parallel-group, Placebo Controlled Study to Evaluate the Efficacy and Safety of IBP-9414 in Premature Infants 500-1500g Birth Weight in the Prevention of Necrotizing Enterocolitis - The Connection Study

Active recruiting

The purpose of the clinical study is to compare the effectiveness of IBP-9414 treatment against placebo in preventing necrotizing enterocolitis in premature infants.

 

Treatments: Prevention of necrotizing enterocolitis in premature infants

Contact: Erin Bauer phone217-545-6955 emailebauer38@siumed.edu
Trial
Neurology

A Randomized, Double-blind, Placebo-controlled, Global Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986446, an Anti-MTBR Tau Monoclonal Antibody, in Participants with Early Alzheimer’s Disease (TargetTau-1)

Active not recruiting

The purpose of this study is to assess the effect of BMS-986446 vs placebo on delay of cognitive memory and functional decline in participants (age 50-80) with early Alzheimer's Disease.

Contact: Stephanie Kohlrus phone217-545-3013 emailskohlrus@siumed.edu
Trial
Neurology

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 as Adjunctive Therapy in Focal-Onset Seizures

Active recruiting

The primary objective of this study is to assess the effect of XEN1101 versus placebo on reducing focal seizure frequency.

Contact: Stephanie Kohlrus phone217-545-3013 emailskohlrus@siumed.edu
Trial
Neurology

A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

Active recruiting

The primary objective is to assess the effect of XEN1101 versus placebo on reducing PGTCS frequency in subjects with PGTCS.

Contact: Stephanie Kohlrus phone217-545-3013 emailskohlrus@siumed.edu
Trial
Urology

A Randomized Open-Label Phase 2/3 Study of BT8009 Monotherapy or in Combination in Participants with Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)

Active recruiting

The main objective of the study is to measure how safe and effective BT8009 (zelenectide pevedotin) is when used alone and in combination with pembrolizumab in participants with locally advanced or metastatic urothelial cancer (UC).

Contact: Kathy Robinson phone217-545-1946 emailsciresearchbc@siumed.edu
Trial
Neurology

A Seamless Phase 2A-Phase 2B Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients with Early Alzheimer’s Disease (BenfoTeam)

Active recruiting

The purpose of this study is to learn more about the safety, effectiveness and tolerability of the study drug called Benfotiamine, to determine whether it delays or slows the progression of the symptoms of early Alzheimer’s disease.

Contact: Stephanie Kohlrus phone217-545-3013 emailskohlrus@siumed.edu
Events

Advanced Hernia Grand Rounds

The SIU Division of General Surgery and the Springfield Memorial Hospital Advanced Hernia Center present Advanced Hernia Grand Rounds with visiting professor, Eric Pauli, MD. Dr. Pauli is the chief of the Division of Minimally Invasive and Bariatric Surgery at the Milton S. Hershey Medical Center and Associate Professor of Surgery and Program Director for the Abdominal Wall Surgery Fellowship at Pennsylvania State University. He developed the “Pauli technique” for parastomal hernia repair, and he will present “Prometheus, Sisyphus and the Challenges of Parastomal Hernia Repair”.
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