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clinical trials

Clinical trials and research studies

At SIU Medicine, our researchers perform clinical trials and research studies with the aim of translating findings into new, more effective treatments.
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Activity Status

  • Active, not recruiting (4)
  • Active, recruiting (12)

Treatment

  • Breast Cancer (2)
  • Diseases of the Lungs (2)
  • Endometrial Cancer (1)
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  • High Blood Pressure (Hypertension) (4)
  • Leukemia (1)
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Department

  • (-) Internal Medicine (8)
  • (-) Simmons Cancer Institute (8)
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Filter Results

Activity Status

  • Active, not recruiting (4)
  • Active, recruiting (12)

Treatment

  • Breast Cancer (2)
  • Diseases of the Lungs (2)
  • Endometrial Cancer (1)
  • Heart Disease (1)
  • High Blood Pressure (Hypertension) (4)
  • Leukemia (1)
  • Myeloma (1)
  • Ovarian Cancer (1)

Department

  • (-) Internal Medicine (8)
  • (-) Simmons Cancer Institute (8)
  • Alzheimer's Center (2)
  • Cardiology (2)
  • Cardiothoracic Surgery (1)
  • Dermatology (1)
  • Infectious Diseases (1)
  • Men's health (1)
  • Neurology (9)
  • Obstetrics and Gynecology (3)
  • Pediatrics (1)
  • Psychiatry (1)
  • Pulmonary and Critical Care (2)
  • Urology (3)
  • Vascular Surgery (2)
  • Women's health (1)
Showing: 16 Results
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Trial
Internal Medicine

HyPhen: Hypertension Phenotype Study

Active recruiting

This is a local research study to relate heart health and various components found in your body (body fat, sodium, etc.) to high blood pressure during pregnancy, and those with apparently normal blood pressure.

Eligible participants include those with high blood pressure, those receiving treatment for their high blood pressure, women who had high blood pressure during pregnancy, and those with apparently normal blood pressure.

Contact: Kristin King phone217-545-7511 emailbpresearch@siumed.edu
Trial
Simmons Cancer Institute

KO-MEN-008: Phase 1 Study to Determine the Safety and Tolerability of Ziftomenib Combinations for the Treatment of KMT2A-rearranged or NPM1-mutant Relapsed/Refractory Acute Myeloid Leukemia

Active recruiting

Examining the safety, tolerability, and effectiveness of investigational drug ziftomenib in combination with standard of care treatments for patients with relapsed/refractory acute myeloid leukemia. The study drug will be examined with the following agents: FLAG-IDA, low-dose cytarabine, and gilteritinib.

Contact: Kathy Robinson phone217-545-1946 emailsciresearchbc@siumed.edu
Trial
Internal Medicine

Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy (PE-TRACT)

Active recruiting

The study is designed to identify the best way to treat pulmonary embolism- with blood thinners alone or blood thinners with catheter directed therapy.

Contact: Katie Mottershaw phone217-545-7387 emailkmottershaw33@siumed.edu
Trial
Internal Medicine

RADIANCE Continued Access Protocol (CAP): A study of the ReCor Medical Paradise System in Clinical Hypertension

Active not recruiting
The purpose of this clinical trial is to find out if a medical device called the Paradise Renal Denervation System can lower blood pressure in patients who have hypertension
Contact: Emily Starkey phone217-545-7511 emailbpresearch@siumed.edu
Trial
Internal Medicine

Radiance US GPS: The Global Paradise® System US Post Approval Study

Active recruiting

The purpose of this clinical study is to evaluate the real-world use of the Paradise Ultrasound Renal Denervation System indicated for patients who are unable to lower their blood pressure with lifestyle changes and medication.

Eligible patients include those who currently have a diagnosis of high blood pressure despite having taken or are currently taking anti-hypertensive medications.

Contact: Katy Martz phone217-545-4342 emailkmartz35@siumed.edu
Trial
Internal Medicine

VICTORION-2 PREVENT: A randomized double-blind, placebo-controlled, multicenter trial, assessing the impact of inclisiran on major adverse cardiovascular events in participants with established cardiovascular disease

Active not recruiting

PURPOSE: The purpose of this clinical trial is to find out if the investigational study treatment, called inclisiran, can help prevent cardiovascular events (such as heart attacks, strokes, and cardiovascular-related deaths) in adults who already have been diagnosed with cardiovascular disease.

Contact: Katie Mottershaw phone217-545-7387 emailkmottershaw33@siumed.edu
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