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clinical trials

Clinical trials and research studies

At SIU Medicine, our researchers perform clinical trials and research studies with the aim of translating findings into new, more effective treatments.
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Activity Status

  • Active, not recruiting (5)
  • Active, recruiting (12)

Treatment

  • Alzheimer's Disease (2)
  • Diseases of the Lungs (2)
  • Epilepsy (4)
  • Heart Disease (1)
  • High Blood Pressure (Hypertension) (4)
  • Neuro-Critical Care (1)
  • Parkinson's Disease (1)
  • Stroke (1)

Department

  • (-) Internal Medicine (8)
  • (-) Neurology (9)
  • Alzheimer's Center (2)
  • Cardiology (2)
  • Cardiothoracic Surgery (1)
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  • Infectious Diseases (1)
  • Men's health (1)
  • Obstetrics and Gynecology (3)
  • Pediatrics (1)
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  • Simmons Cancer Institute (8)
  • Urology (3)
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Reset

Filter Results

Activity Status

  • Active, not recruiting (5)
  • Active, recruiting (12)

Treatment

  • Alzheimer's Disease (2)
  • Diseases of the Lungs (2)
  • Epilepsy (4)
  • Heart Disease (1)
  • High Blood Pressure (Hypertension) (4)
  • Neuro-Critical Care (1)
  • Parkinson's Disease (1)
  • Stroke (1)

Department

  • (-) Internal Medicine (8)
  • (-) Neurology (9)
  • Alzheimer's Center (2)
  • Cardiology (2)
  • Cardiothoracic Surgery (1)
  • Dermatology (1)
  • Infectious Diseases (1)
  • Men's health (1)
  • Obstetrics and Gynecology (3)
  • Pediatrics (1)
  • Psychiatry (1)
  • Pulmonary and Critical Care (2)
  • Simmons Cancer Institute (8)
  • Urology (3)
  • Vascular Surgery (2)
  • Women's health (1)
Showing: 17 Results
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Trial
Internal Medicine

HyPhen: Hypertension Phenotype Study

Active recruiting

This is a local research study to relate heart health and various components found in your body (body fat, sodium, etc.) to high blood pressure during pregnancy, and those with apparently normal blood pressure.

Eligible participants include those with high blood pressure, those receiving treatment for their high blood pressure, women who had high blood pressure during pregnancy, and those with apparently normal blood pressure.

Contact: Kristin King phone217-545-7511 emailbpresearch@siumed.edu
Trial
Internal Medicine

Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy (PE-TRACT)

Active recruiting

The study is designed to identify the best way to treat pulmonary embolism- with blood thinners alone or blood thinners with catheter directed therapy.

Contact: Katie Mottershaw phone217-545-7387 emailkmottershaw33@siumed.edu
Trial
Internal Medicine

RADIANCE Continued Access Protocol (CAP): A study of the ReCor Medical Paradise System in Clinical Hypertension

Active not recruiting
The purpose of this clinical trial is to find out if a medical device called the Paradise Renal Denervation System can lower blood pressure in patients who have hypertension
Contact: Emily Starkey phone217-545-7511 emailbpresearch@siumed.edu
Trial
Internal Medicine

Radiance US GPS: The Global Paradise® System US Post Approval Study

Active recruiting

The purpose of this clinical study is to evaluate the real-world use of the Paradise Ultrasound Renal Denervation System indicated for patients who are unable to lower their blood pressure with lifestyle changes and medication.

Eligible patients include those who currently have a diagnosis of high blood pressure despite having taken or are currently taking anti-hypertensive medications.

Contact: Katy Martz phone217-545-4342 emailkmartz35@siumed.edu
Trial
Neurology

Roche: A Phase IIB, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of intravenous prasinezumab in participants with early Parkinson's disease

Active not recruiting

This study will evaluate the efficacy, safety, and pharmacokinetics of prasinezumab compared with placebo in patients with early Parkinson's disease (PD).

Contact: Rylee Manka phone217-545-1394 emailrmanka63@siumed.edu
Trial
Neuroscience Institute

Sleep for Stroke Management and Recovery Trial

Active recruiting

The primary goals of this study are to determine whether treatment of obstructive sleep apnea with positive airway pressure starting shortly after accute ischemic stroke or high risk TIA (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event and (2) improves stroke outcomes at 3 months in patients who experienced ischemic stroke.

Contact: Stephanie Kohlrus phone217-545-3013 emailskohlrus@siumed.edu
Trial
Internal Medicine

VICTORION-2 PREVENT: A randomized double-blind, placebo-controlled, multicenter trial, assessing the impact of inclisiran on major adverse cardiovascular events in participants with established cardiovascular disease

Active not recruiting

PURPOSE: The purpose of this clinical trial is to find out if the investigational study treatment, called inclisiran, can help prevent cardiovascular events (such as heart attacks, strokes, and cardiovascular-related deaths) in adults who already have been diagnosed with cardiovascular disease.

Contact: Katie Mottershaw phone217-545-7387 emailkmottershaw33@siumed.edu
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