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clinical trials

Clinical trials and research studies

At SIU Medicine, our researchers perform clinical trials and research studies with the aim of translating findings into new, more effective treatments.
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Activity Status

  • (-) Active, recruiting (7)
  • Active, not recruiting (5)

Treatment

  • (-) Alzheimer's Disease (4)
  • (-) High Blood Pressure (Hypertension) (3)
  • Autism Spectrum Disorder (1)
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  • Ovarian Cancer (4)
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  • Transcranial Magnetic Stimulation (TMS) (1)
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Department

  • Alzheimer's Center (2)
  • Internal Medicine (2)
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Filter Results

Activity Status

  • (-) Active, recruiting (7)
  • Active, not recruiting (5)

Treatment

  • (-) Alzheimer's Disease (4)
  • (-) High Blood Pressure (Hypertension) (3)
  • Autism Spectrum Disorder (1)
  • Breast Cancer (3)
  • Cervical Cancer (1)
  • Depression (1)
  • Diseases of the Lungs (2)
  • Endometrial Cancer (1)
  • Endometriosis (1)
  • Epilepsy (9)
  • Erectile Dysfunction (ED) (1)
  • Heart Disease (1)
  • Leukemia (1)
  • Male Infertility (1)
  • Melanoma (1)
  • Myeloma (1)
  • Ovarian Cancer (4)
  • Psoriasis (1)
  • Stroke (3)
  • Transcranial Magnetic Stimulation (TMS) (1)
  • Vascular Disease (1)

Department

  • Alzheimer's Center (2)
  • Internal Medicine (2)
  • Neurology (2)
Showing: 7 Results
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Trial
Neurology

A Seamless Phase 2A-Phase 2B Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients with Early Alzheimer’s Disease (BenfoTeam)

Active recruiting

The purpose of this study is to learn more about the safety, effectiveness and tolerability of the study drug called Benfotiamine, to determine whether it delays or slows the progression of the symptoms of early Alzheimer’s disease.

Contact: Stephanie Kohlrus phone217-545-3013 emailskohlrus@siumed.edu
Trial
Neurology

ADCS Benfo: A Seamless Phase 2A-Phase 2B Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients with Early Alzheimer’s Disease (BenfoTeam)

Active recruiting

The purpose of this study is to learn more about the safety, effectiveness and tolerability of the study dr

Contact: Stephanie Kohlrus phone217-545-3013 emailskohlrus@siumed.edu
Trial
Neurology

Caregiver Characteristics That May Be Associated with the Optimal Care of Patients with Alzheimer's Disease

Active recruiting

The purpose of this study is to investigate several factors that would appear to have face value relevance

Contact: Stephanie Kohlrus phone217-545-3013 emailskohlrus@siumed.edu
Trial
Neurology

Caregiver Characteristics That May Predict When Patients With Alzheimer Disease Are Placed in Long Term Care Facilities

Active recruiting
This research will be conducted by the SIU Memory and Aging Network (MAN), which comprises 38 sites that evaluate and treat patients with dementia throughout non-metropolitan Illinois.  AD patients and their caregivers who are living in private homes will be recruited.  Primary outcome measures will be the ratings of the caregiver’s physical status (grip strength, walking speed, and score on the Timed Up-and-Go Test11 and the rating of the caregiver’s chronic medical illness burden using the Cumulative Illness Rating Scale (Geriatric).12,13  The patient and caregiver dyad is required.
Contact: Stephanie Kohlrus phone217-545-3013 emailskohlrus@siumed.edu
Trial
Internal Medicine

HyPhen: Hypertension Phenotype Study

Active recruiting

This is a local research study to relate heart health and various components found in your body (body fat, sodium, etc.) to high blood pressure during pregnancy, and those with apparently normal blood pressure.

Eligible participants include those with high blood pressure, those receiving treatment for their high blood pressure, women who had high blood pressure during pregnancy, and those with apparently normal blood pressure.

Contact: Kristin King phone217-545-7511 emailbpresearch@siumed.edu
Trial
Internal Medicine

Radiance US GPS: The Global Paradise® System US Post Approval Study

Active recruiting

The purpose of this clinical study is to evaluate the real-world use of the Paradise Ultrasound Renal Denervation System indicated for patients who are unable to lower their blood pressure with lifestyle changes and medication.

Eligible patients include those who currently have a diagnosis of high blood pressure despite having taken or are currently taking anti-hypertensive medications.

Contact: Katy Martz phone217-545-4342 emailkmartz35@siumed.edu
Trial
Internal Medicine

THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System vs. Sham for the Adjunctive Treatment of Hypertension

Active recruiting

The purpose of this clinical trial is to assess whether a medical device called the TIVUS System can lower high blood pressure in patients who are known to have hypertension. 

Eligible patients include those who currently have a diagnosis of high blood pressure despite having taken or currently taking anti-hypertensive medications.

Contact: Katy Martz phone217-545-4342 emailkmartz35@siumed.edu
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