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clinical trials

Clinical trials and research studies

At SIU Medicine, our researchers perform clinical trials and research studies with the aim of translating findings into new, more effective treatments.
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Activity Status

  • (-) Active, not recruiting (11)
  • Active, recruiting (36)

Treatment

  • Abdominal Aortic Aneurysm (1)
  • Alzheimer's Disease (1)
  • Heart Disease (1)
  • High Blood Pressure (Hypertension) (5)
  • Neuro-Critical Care (1)
  • Parkinson's Disease (1)

Department

  • Alzheimer's Center (1)
  • Cardiology (2)
  • Internal Medicine (3)
  • Neurology (3)
  • Urology (1)
  • Vascular Surgery (1)
Reset

Filter Results

Activity Status

  • (-) Active, not recruiting (11)
  • Active, recruiting (36)

Treatment

  • Abdominal Aortic Aneurysm (1)
  • Alzheimer's Disease (1)
  • Heart Disease (1)
  • High Blood Pressure (Hypertension) (5)
  • Neuro-Critical Care (1)
  • Parkinson's Disease (1)

Department

  • Alzheimer's Center (1)
  • Cardiology (2)
  • Internal Medicine (3)
  • Neurology (3)
  • Urology (1)
  • Vascular Surgery (1)
Showing: 11 Results
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Trial
Neuroscience Institute

18-513: A Randomized Clinical Trial of Andexanet Alfa in Acute Intracranial Hemorrhage in Patients Receiving an Oral Factor XA Inhibitor

Active not recruiting

18-513:  The purpose of this study is to evaluate the effect of andexanet alfa (andexanet) versus usual care on the rate of effective homostasis.

Contact: Stephanie Kohlrus phone217-545-3013 emailskohlrus@siumed.edu
Trial
Neurology

A Randomized, Double-blind, Placebo-controlled, Global Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986446, an Anti-MTBR Tau Monoclonal Antibody, in Participants with Early Alzheimer’s Disease (TargetTau-1)

Active not recruiting

The purpose of this study is to assess the effect of BMS-986446 vs placebo on delay of cognitive memory and functional decline in participants (age 50-80) with early Alzheimer's Disease.

Contact: Stephanie Kohlrus phone217-545-3013 emailskohlrus@siumed.edu
Trial
Vascular Surgery

Assessment of the GORE® EXCLUDER® Conformable AAA Endoprosthesis in the Treatment of Abdominal Aortic Aneurysms: AAA 13-03

Active not recruiting

The purpose of this study is to assess the safety and effectiveness of the GORE® EXCLUDER® Conformable AAA Endoprosthesis (Study Device) when used for the treatment of Abdominal Aortic Aneurysms (AAA).

Contact: Kristal Adams phone217-545-7812 emailkadams@siumed.edu
Trial
Internal Medicine

AstraZeneca BaxHTN: A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study to Assess the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypert

Active not recruiting

The purpose of this clinical trial is to trial is to learn more about a new, investigational, once daily medication, called baxdrostat, and its ability to lower blood pressure in individuals not responding to their current treatment.

Contact: Emily Starkey phone217-545-7616 emailestarkey74@siumed.edu
Trial
Internal Medicine

Mineralys (MLS-101-202): A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, PARALLEL ARM, MULTI-CENTER, PHASE 2 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF LORUNDROSTAT IN SUBJECTS WITH UNCONTROLLED HYPERTENSION ON A STANDARDIZED MEDICATION REGIMEN

Active not recruiting

The purpose of this clinical trial is to assess the blood pressure lowering effects of lorundrostat, taken once daily, in patients with high blood pressure.

Contact: Emily Starkey phone217-545-7511 emailbpresearch@siumed.edu
Trial
Internal Medicine

Mineralys MLS-101-301 A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, PARALLEL ARM, MULTICENTER PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF LORUNDROSTAT IN SUBJECTS WITH UNCONTROLLED AND RESISTANT HYPERTENSION

Active not recruiting

The purpose of this clinical trial is to assess the blood pressure lowering effects of lorundrostat, taken once daily, in patients with high blood pressure.

Contact: Emily Starkey phone217-545-7616 emailestarkey74@siumed.edu
Trial
Urology

ProVIDE: The ProVee Urethral Expander System Study: The ProVee IDE Study

Active not recruiting

The study will test whether the study device, the ProVee Urethral Expander System, can be placed in your urethra safely to treat your urinary symptoms due to your enlarged prostate.

Contact: Katharine Blancett phone217-545-7799 emailkblancett37@siumed.edu
Trial
Internal Medicine

RADIANCE Continued Access Protocol (CAP): A study of the ReCor Medical Paradise System in Clinical Hypertension

Active not recruiting
The purpose of this clinical trial is to find out if a medical device called the Paradise Renal Denervation System can lower blood pressure in patients who have hypertension
Contact: Emily Starkey phone217-545-7511 emailbpresearch@siumed.edu
Trial
Neurology

Roche: A Phase IIB, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of intravenous prasinezumab in participants with early Parkinson's disease

Active not recruiting

This study will evaluate the efficacy, safety, and pharmacokinetics of prasinezumab compared with placebo in patients with early Parkinson's disease (PD).

Contact: Rylee Manka phone217-545-1394 emailrmanka63@siumed.edu
Trial
Cardiology

The "RADIANCE II" Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension

Active not recruiting
The purpose of this clinical study is to see whether a medical device called the Paradise Renal Denervation System (also called The Paradise System) can lower high blood pressure in patients who are known to have hypertension
Contact: Emily Starkey phone217-545-7616 emailestarkey74@siumed.edu
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