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clinical trials

Clinical trials and research studies

At SIU Medicine, our researchers perform clinical trials and research studies with the aim of translating findings into new, more effective treatments.
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Activity Status

  • Active, not recruiting (11)
  • Active, recruiting (40)

Treatment

  • Abdominal Aortic Aneurysm (1)
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Reset

Filter Results

Activity Status

  • Active, not recruiting (11)
  • Active, recruiting (40)

Treatment

  • Abdominal Aortic Aneurysm (1)
  • Alzheimer's Disease (4)
  • Autism Spectrum Disorder (1)
  • Breast Cancer (3)
  • Cervical Cancer (1)
  • Depression (1)
  • Diseases of the Lungs (2)
  • Endometrial Cancer (1)
  • Endometriosis (1)
  • Epilepsy (9)
  • Erectile Dysfunction (ED) (1)
  • Heart Disease (2)
  • High Blood Pressure (Hypertension) (8)
  • Leukemia (1)
  • Male Infertility (1)
  • Melanoma (1)
  • Myeloma (1)
  • Neuro-Critical Care (1)
  • Ovarian Cancer (4)
  • Parkinson's Disease (1)
  • Psoriasis (1)
  • Stroke (3)
  • Transcranial Magnetic Stimulation (TMS) (1)
  • Vascular Disease (1)

Department

  • Alzheimer's Center (2)
  • Cardiology (2)
  • Cardiothoracic Surgery (1)
  • Dermatology (1)
  • Infectious Diseases (1)
  • Internal Medicine (8)
  • Men's health (1)
  • Neurology (9)
  • Obstetrics and Gynecology (3)
  • Pediatrics (1)
  • Psychiatry (1)
  • Pulmonary and Critical Care (2)
  • Simmons Cancer Institute (8)
  • Urology (3)
  • Vascular Surgery (2)
  • Women's health (1)
Showing: 51 Results
search
Trial
Surgery

LeAAPS

Active recruiting

Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction

Contact: Katie Blancett phone217-545-7799 emailkblancett37@siumed.edu
Trial
Internal Medicine

Mineralys (MLS-101-202): A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, PARALLEL ARM, MULTI-CENTER, PHASE 2 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF LORUNDROSTAT IN SUBJECTS WITH UNCONTROLLED HYPERTENSION ON A STANDARDIZED MEDICATION REGIMEN

Active not recruiting

The purpose of this clinical trial is to assess the blood pressure lowering effects of lorundrostat, taken once daily, in patients with high blood pressure.

Contact: Emily Starkey phone217-545-7511 emailbpresearch@siumed.edu
Trial
Internal Medicine

Mineralys MLS-101-301 A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, PARALLEL ARM, MULTICENTER PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF LORUNDROSTAT IN SUBJECTS WITH UNCONTROLLED AND RESISTANT HYPERTENSION

Active not recruiting

The purpose of this clinical trial is to assess the blood pressure lowering effects of lorundrostat, taken once daily, in patients with high blood pressure.

Contact: Emily Starkey phone217-545-7616 emailestarkey74@siumed.edu
Trial
Urology

ProVIDE: The ProVee Urethral Expander System Study: The ProVee IDE Study

Active not recruiting

The study will test whether the study device, the ProVee Urethral Expander System, can be placed in your urethra safely to treat your urinary symptoms due to your enlarged prostate.

Contact: Katharine Blancett phone217-545-7799 emailkblancett37@siumed.edu
Trial
Internal Medicine

Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy (PE-TRACT)

Active recruiting

The study is designed to identify the best way to treat pulmonary embolism- with blood thinners alone or blood thinners with catheter directed therapy.

Contact: Katie Mottershaw phone217-545-7387 emailkmottershaw33@siumed.edu
Trial
Internal Medicine

RADIANCE Continued Access Protocol (CAP): A study of the ReCor Medical Paradise System in Clinical Hypertension

Active not recruiting
The purpose of this clinical trial is to find out if a medical device called the Paradise Renal Denervation System can lower blood pressure in patients who have hypertension
Contact: Emily Starkey phone217-545-7511 emailbpresearch@siumed.edu
Trial
Internal Medicine

Radiance US GPS: The Global Paradise® System US Post Approval Study

Active recruiting

The purpose of this clinical study is to evaluate the real-world use of the Paradise Ultrasound Renal Denervation System indicated for patients who are unable to lower their blood pressure with lifestyle changes and medication.

Eligible patients include those who currently have a diagnosis of high blood pressure despite having taken or are currently taking anti-hypertensive medications.

Contact: Katy Martz phone217-545-4342 emailkmartz35@siumed.edu
Trial
Internal Medicine

RECHARGE

Active recruiting

To compare the effect of percutaneous coronary intervention (PCI) vs coronary artery bypass grafting (CABG)

Contact: Katie Mottershaw phone217-545-7387 emailkmottershaw33@siumed.edu
Trial
Psychiatry

RECOVER: A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy System as Adjunctive Therapy Versus a No-Stimulation Control in Subjects with Treatment-Resistant Depression

Active recruiting

The RECOVER study is a nationwide clinical trial that has been approved by Medicare to provide additional evidence for the benefits of Vagus Nerve Stimulation (VNS) Therapy.  Vagus Nerve Stimulation Therapy is an FDA-approved device for treating patients with TRD (Treatment Resistant Depression). It is implanted in the left chest area during a short outpatient procedure. The device delivers mild, intermittently pulsed signals to the vagus nerve in the neck that activate various parts of the brain.

Contact: Oladele (Dickson) Owasoyo phone217-545-7231 emailoowasoyo94@siumed.edu
Trial
Neurology

Renaissance 2: A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Parallel-Group Study to Evaluate the Efficacy, Safety, and Tolerability of SPN-817 in Adults with Focal Onset Seizures

Active recruiting

To evaluate the efficacy of SPN-817 as a treatment for adult participants with focal onset seizures.

Contact: Stephanie Kohlrus phone217-545-3013 emailskohlrus@siumed.edu
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