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Research Overview

image of researcherThe SIU Division of Urology has the capability, experience, and dedication to research new techniques and technology to aid in the advancement of patient diagnosis,  management, and education across many pathologies in Urology.  Our goal is to become a well-rounded department involved in the full spectrum of research.  We have the ability to participate in the latest industry sponsored clinical drug and device trials for prostate cancer, erectile dysfunction, and BPH to name a few.  All faculty physicians have initiated their own projects with successful funding from NIH, industry, and local grant opportunities.  We also acknowledge the importance of collaboration by forging partnerships with other universities and visiting professors throughout the country. Aside from the clinical research, the division also has two laboratories to conduct basic science experiments.  Not only does our vast involvement in research benefit our patients with state of the art care, but it also allows our medical students and residents to be involved in the forefront of this innovation.





Some of the Urology Current Studies

  • Myrbetriq™ (Mirabegron) to Improve Ureteral Stent Related Pain and Discomfort - Ahmed El-Zawahry, MD
  • Intracorporeal Versus Extracorporeal Urinary Diversion with Robotic-Assisted Radical Cystectomy – Ahmed El-Zawahry, MD
  • Myrbetriq™ (Mirabegron) to Improve Disordered Sleep in Subjects with Lower Urinary Tract symptoms (LUTS) -  Kevin McVary, MD
  • Bladder Biopsy as a Predictor of Botulinum Toxin Effectiveness in Overactive Bladder - Kevin McVary, MD
  • 3-Way Approach for Erectile Dysfunction Prevention - Kevin McVary, MD
  • Effects of Bariatric Surgery on LUTS/BPH: A Pilot Study - Kevin McVary, MD
  • Minimally Invasive Prostatic Vapor Ablation - Multicenter, Randomized, Controlled Study for the Treatment of BPH (Rezūm II)  - Kevin McVary, MD
  • A Single-Country, Multicenter, Single-Arm Study of the Effects of Atrasentan on Spermatogenesis and Testicular Function - Tobias Köhler, MD, MPH
  • Prospective Registry of Outcomes with Penile Prosthesis for Erectile Restoration (PROPPER) - Tobias Köhler, MD, MPH
  • CUPPID Study: Cardiac & Urologic Pathology/Prevalence Interplay Determination Study – Tobias Köhler, MD, MPH
  • EEG Activity  and Attention During Robotic Surgery - Bradley Schwartz, DO
  • Oncologic and Clinical Outcomes for Renal Mass Ablation with Cryotherapy  - Bradley Schwartz, DO
  • Gastric Secretions Causing Ureteral Dilation: A Rodent Model – Bradley Schwartz, DO
  • Evaluation of the AAP Guidelines for the Evaluation of Children Presenting with Urinary Tract Infections - Ranjiv Mathews, MD


Urology Faculty Research Interests

Kevin T. McVary, MD, FACS

  • Medical and procedural treatment of Lower Urinary Tract Symptoms (LUTS) / Benign Prostatic Hyperplasia (BPH)
  • Prostate Cancer “Active Surveillance”
  • Population based medicine assessing trends in urological diagnosis and treatment
  • Rural medicine: providing specialized urologic care to underserved areas
  • Preservation of sexual function in treatment of prostate pathologies
  • Prostatectomies and Incontinence
  • Mechanisms of neuromuscular transmission and its modulation in overactive bladder
  • Sonic Hedghog Pathway: essential regulator of penile smooth muscle, cavernous nerve integrity and central nerve regeneration
  • Erectile dysfunction therapies


Bradley Schwartz, DO, FACS

  • Resident Education
  • Surgical skills assessment and simulation
  • Percutaneous nephrolithotomy
  • Kidney stones
  • Device development
  • Laparoscopic and robotic renal surgery


Ahmed El-Zawahry, MD

  • UTI in women pre- and postmenopausal
  • Causes and treatment of female prolapse
  • Salvage procedures for sling procedures
  • Management of stress urinary incontinence with periurethral bulking agents
  • Management of neurogenic bladder using botox injection, interstim, or urinary diversion
  • Causes and treatment of overactive bladder using different approaches such as interstim, PTNS, and botox injection
  • Management of urinary retention
  • Management of male stress urinary incontinence
  • Quality of life in patient treated for neurogenic and overactive bladder


Ranjiv I. Mathews, MD

  • Pediatric Urology
  • Hypospadias
  • Environmental impact on fetal development
  • Bladder Extrophy
  • Voiding dysfunction
  • Bowel Bladder Dysfunction
  • Analgesia in penile surgeries


Sohail Siddique, MD

  • Pelvic floor disorders
  • Urinary dysfunction and quality of life
  • Interstim and Neuromodulation
  • Sexual function in patients with prolapse and incontinence