Erin Hascup Lab

    Overview

    Alzheimer’s disease is an age-related neurodegenerative disorder that over time leads to severe memory impairment and greatly impacts patients and their loved ones. There is no cure or effective treatment for Alzheimer’s disease and recent evidence support early intervention as essential for improving disease outcome. 

    Our lab is dedicated to finding effective preventions and treatments for Alzheimer’s disease. Research emphasis is on determining risk factors, and their associated mechanisms, that contribute to memory loss and Alzheimer’s disease that will allow for earlier diagnosis and treatment to improve patient outcome. To accomplish this, we focus on discovery of early biomarkers and intervention strategies, primarily in the areas of neurotransmission, inflammation, and cell senescence, in combination with cognitive assessments.

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    Erin R. Hascup, PhD Primary Investigator

    Director, Dale and Deborah Smith Center for Alzheimer’s Research and Treatment, Associate Professor of Neurology

    Research Focus

    CURRENT PROJECTS

    • Neurotransmitter Regulation in AD (NIH R01 AG057767)
    • Early Intervention in AD
    • Cell senescence in aging and AD (NIH R01 AG061937)
    • Inflammation in aging and AD (NIH R01 AG061937)
    • Disease Stage Specific AD Therapies (NIH R01 AG057767)
    • Cell senescence in epilepsy

    News

    Introducing the Dale and Deborah Smith Center

    A major gift to SIU School of Medicine will transform the health care of people throughout Illinois and beyond. Springfield couple Dale and Deborah Smith donated a substantial financial gift to the
    Bain Scan

    SIU School of Medicine receives major gift for Alzheimers research

    A major gift to Southern Illinois University School of Medicine will transform the health care of people throughout Illinois and beyond. Dale and Deborah Smith recently donated a substantial financial